Zobrazeno 1 - 10
of 275
pro vyhledávání: '"Sang Chul Shin"'
Autor:
Sang Chul Shin, Jinyoung Park, Kyung Hee Kim, Jung Min Yoon, Jinhong Cho, Byung Hak Ha, Yeonji Oh, Hyunah Choo, Eun Joo Song, Eunice EunKyeong Kim
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract USP47 is widely involved in tumor development, metastasis, and other processes while performing a more regulatory role in inflammatory responses, myocardial infarction, and neuronal development. In this study, we investigate the functional a
Externí odkaz:
https://doaj.org/article/57296f0726274b48b57ffd08a439e4a8
Autor:
Eun Young Jeon, Da‐som Choi, Seunghyun Choi, Ju‐young Won, Yunju Jo, Hye‐bin Kim, Youngmee Jung, Sang Chul Shin, Hophil Min, Hae Woong Choi, Myeong Sup Lee, Yoon Park, Justin J. Chung, Hyung‐seung Jin
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)
Abstract Adoptive cell therapy (ACT) with antigen‐specific T cells is a promising treatment approach for solid cancers. Interleukin‐2 (IL‐2) has been utilized in boosting the efficacy of ACT. However, the clinical applications of IL‐2 in comb
Externí odkaz:
https://doaj.org/article/cb2daf617e7d480ab04c6bf1711ee83a
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100871- (2021)
Human prostaglandin E2 receptor 4 (EP4) is one of the four subtypes of prostaglandin E2 (PGE2) receptors and belongs to the rhodopsin-type G protein-coupled receptor (GPCR) family. Particularly, EP4 is expressed in various cancer cells and is involve
Externí odkaz:
https://doaj.org/article/38aa0f661d7d4611917aaf9ccc70369d
Autor:
Seong-Hyun Park, Won-Je Kim, Hui Li, Wonil Seo, Sang-Hyun Park, Hwan Kim, Sang Chul Shin, Erik R. P. Zuiderweg, Eunice EunKyeong Kim, Taebo Sim, Nak-Kyoon Kim, Injae Shin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract In this study we examined the anti-leukemia activity of a small molecule inhibitor of Hsp70 proteins, apoptozole (Az), and hybrids in which it is linked to an inhibitor of either Hsp90 (geldanamycin) or Abl kinase (imatinib). The results of
Externí odkaz:
https://doaj.org/article/c293a04a3a7f4e7ea36a495332a1bd11
Autor:
Sang Chul Shin, Sun-Kyoung Im, Eun-Hae Jang, Kyeong Sik Jin, Eun-Mi Hur, Eunice EunKyeong Kim
Publikováno v:
Cell Reports, Vol 26, Iss 5, Pp 1357-1367.e5 (2019)
Summary: Katanin was the first microtubule (MT)-severing enzyme discovered, but how katanin executes MT severing remains poorly understood. Here, we report X-ray crystal structures of the apo and ATPγS-bound states of the catalytic AAA domain of hum
Externí odkaz:
https://doaj.org/article/5edffdc483ac4088863e58112c52ba6a
Autor:
Sang Chul Shin, Ashraf K. El-Damasy, Ju Hyeon Lee, Seon Hee Seo, Ji Hyun Kim, Young Ho Seo, Yuri Lee, Ji Hoon Yu, Eun Kyoung Bang, Eunice EunKyeong Kim, Gyochang Keum
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9377 (2020)
Inhibition of the molecular chaperone heat shock protein 90 (Hsp90) represents a promising approach for cancer treatment. BIIB021 is a highly potent Hsp90 inhibitor with remarkable anticancer activity; however, its clinical application is limited by
Externí odkaz:
https://doaj.org/article/b656d25f15164aa1888f5f70a350f138
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4028 (2020)
Ubiquitination and deubiquitination play a critical role in all aspects of cellular processes, and the enzymes involved are tightly regulated by multiple factors including posttranslational modifications like most other proteins. Dysfunction or misre
Externí odkaz:
https://doaj.org/article/2836a3f616714d2aa118459850ae9b74
Autor:
Yaqin Bai, Hui Lei, Wenjun Song, Sang-Chul Shin, Jiaqi Wang, Biying Xiao, Zeynep A. Koçer, Min-Suk Song, Robert Webster, Richard J. Webby, Sook-San Wong, Mark Zanin
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
A diverse population of avian influenza A viruses (AIVs) are maintained in wild birds and ducks yet the zoonotic potential of AIVs in these environmental reservoirs and the host-virus interactions involved in mammalian infection are not well understo
Externí odkaz:
https://doaj.org/article/411295d31fac474f9a9f9f803fac9b85
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e34139- (2024)
We have examined whether the copper reduction slag (CRS) generated after recovering valuable metals from copper slag (CS) by reduction process can be used as supplementary cementitious materials (SCMs). According to the test results, the Cu secondary
Externí odkaz:
https://doaj.org/article/6f7f54d7f34648db911ad7d71882bac5
Autor:
Jinyoung Park, Sang Chul Shin, Kyeong Sik Jin, Min Joon Lim, Yeojin Kim, Eunice EunKyeong Kim, Eun Joo Song
Publikováno v:
Cellular and Molecular Life Sciences. 80