Zobrazeno 1 - 10
of 258
pro vyhledávání: '"Sang‐Jun Ha"'
Autor:
Dinh-Huy Nguyen, Sung-Hwan You, Hien Thi-Thu Ngo, Khuynh Van Nguyen, Khang Vuong Tran, Tan-Huy Chu, So-young Kim, Sang-Jun Ha, Yeongjin Hong, Jung-Joon Min
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Synergistic combinations of immunotherapeutic agents can improve the performance of anti-cancer therapies but may lead to immune-mediated adverse effects. These side-effects can be overcome by using a tumor-specific delivery system. Here, we
Externí odkaz:
https://doaj.org/article/b576ac3584e64476b87361f24f3c58bb
Autor:
Yaechan Song, Heeju Na, Seung Eon Lee, You Min Kim, Jihyun Moon, Tae Wook Nam, Yul Ji, Young Jin, Jae Hyung Park, Seok Chan Cho, Jaehoon Lee, Daehee Hwang, Sang-Jun Ha, Hyun Woo Park, Jae Bum Kim, Han-Woong Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Obesity has emerged as a prominent risk factor for the development of malignant tumors. However, the existing literature on the role of adipocytes in the tumor microenvironment (TME) to elucidate the correlation between obesity and cancer re
Externí odkaz:
https://doaj.org/article/60d4f93da40e407caff336bcf08b78b1
Autor:
Nayeon Kim, Chan Yeong Kim, Junyeong Ma, Sunmo Yang, Dong Jin Park, Sang-Jun Ha, Peter Belenky, Insuk Lee
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Mouse gut microbiome research is pivotal for understanding the human gut microbiome, providing insights into disease modeling, host-microbe interactions, and the dietary influence on the gut microbiome. To enhance the translational value of mouse gut
Externí odkaz:
https://doaj.org/article/8835d8a79ab141e9940b5fbb2300b564
Autor:
Hye Ryun Kim, Da Hee Kim, Jung Eun Lee, Chang Gon Kim, Gamin Kim, Seyeon Park, Sang-Jun Ha, Jae-Won Cho, Martin Hemberg, Junha Cha, Euijeong Sung, Seungbyn Baek, Min Hee Hong, Nam Suk Sim, Hyun Jun Hong, Sun Ock Yoon, Yoon Woo Koh, Insuk Lee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Background Oropharyngeal squamous cell carcinoma (OPSCC) induced by human papillomavirus (HPV-positive) is associated with better clinical outcomes than HPV-negative OPSCC. However, the clinical benefits of immunotherapy in patients with HPV-positive
Externí odkaz:
https://doaj.org/article/41f10413d0f440bdbb6c94e5f872b2a8
Autor:
Yaechan Song, Heeju Na, Seung Eon Lee, You Min Kim, Jihyun Moon, Tae Wook Nam, Yul Ji, Young Jin, Jae Hyung Park, Seok Chan Cho, Jaehoon Lee, Daehee Hwang, Sang-Jun Ha, Hyun Woo Park, Jae Bum Kim, Han-Woong Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/857dafac0070417eb68e3131fe999e6a
Autor:
Seungbo Yoo, Yun Hee Jeong, Hong-Hee Choi, Sehyun Chae, Daehee Hwang, Sung Jae Shin, Sang-Jun Ha
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 5, Pp 999-1012 (2023)
Abstract Chronic viral infection impairs systemic immunity in the host; however, the mechanism underlying the dysfunction of immune cells in chronic viral infection is incompletely understood. In this study, we studied the lineage differentiation of
Externí odkaz:
https://doaj.org/article/2d70b49057364b869f851817bfc7cd93
Autor:
Jeongeun Park, Haiying Zhang, Hyun Jung Kwak, Changdev Gorakshnath Gadhe, Yeomyeong Kim, Hyejeong Kim, Minyoung Noh, Dongyun Shin, Sang-Jun Ha, Young-Guen Kwon
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Inhibition of angiogenesis is considered a promising therapeutic approach for cancer treatment. Our previous genetic research showed that the use of a cell-penetrating peptide to inhibit the pleckstrin homology (PH) domain of 3-phosphoinositide-depen
Externí odkaz:
https://doaj.org/article/c960638ed2504fbb88d84d46bfceccf6
Autor:
Kwang H. Kim, Yusook Chung, Ji-Won Huh, Dong Jin Park, Yejin Cho, Yeseul Oh, Haengdueng Jeong, Jaekyung Yoon, Ju-Hee Kang, Hae-Sol Shin, Hyoung-Chin Kim, Soon-Kyeong Kwon, Kyoung Yul Seo, Seung Hyun Oh, Je Kyung Seong, Sang-Jun Ha, Ki Taek Nam, Jihyun F. Kim
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Background Aging is a natural process that an organism gradually loses its physical fitness and functionality. Great efforts have been made to understand and intervene in this deteriorating process. The gut microbiota affects host physiology
Externí odkaz:
https://doaj.org/article/c920cfd3a23340029e16e77641f7f227
Autor:
Tae Gun Kang, Kee Woong Kwon, Kyungsoo Kim, Insuk Lee, Myeong Joon Kim, Sang-Jun Ha, Sung Jae Shin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Viral coinfection alongside mycobacterium tuberculosis (Mtb) infection may lead to immune complications or interference with immune responses. Here the authors show that in mice infected with Mtb and LCMV virus the specific TH1 response to MTb is red
Externí odkaz:
https://doaj.org/article/e9f3bc112bd94dec938789f5b164586c
Autor:
Jae-Won Cho, Seyeon Park, Gamin Kim, Heonjong Han, Hyo Sup Shim, Sunhye Shin, Yong-Soo Bae, Seong Yong Park, Sang-Jun Ha, Insuk Lee, Hye Ryun Kim
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
EGFR mutant lung tumours do not respond favourably to immunotherapy. Here, using single cell sequencing, the authors find that tissue resident memory CD8+ T like cells are reduced in the immune landscape of EGFR mutant tumours in comparison to wild t
Externí odkaz:
https://doaj.org/article/af595a4fd0234e34ba5673acf338be2c