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pro vyhledávání: '"Sanford H. Stone"'
Chronic relapsing experimental allergic encephalomyelitis (EAE) in inbred Strain 13 guinea pigs, a laboratory model highly reminiscent of multiple sclerosis (MS) clinically, pathologically and immunologically, has been applied to therapeutic problems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6835b25a0722cf3d7ef25ac1a7ca305c
https://doi.org/10.1159/000408056
https://doi.org/10.1159/000408056
Association of hereditary cataracts in strain guinea-pigs with mutation of the gene for ζ-crystallin
Autor:
Diana F. Amsbaugh, Manuel B. Datiles, Tian Sheng Hu, Qing Ling Huang, Sanford H. Stone, Xin Yu Du, J. Samuel Zigler
Publikováno v:
Experimental Eye Research. 50:317-325
Congenital nuclear cataracts transmitted by an autosomal dominant gene are present in a line of strain 13 N guinea-pigs. Studies on the lens proteins from these animals demonstrate changes in both the composition and structure of the crystallins rela
Publikováno v:
Ophthalmic Research. 13:129-138
Juvenile guinea pigs developed cataracts during severe acute allergic (autoimmune) encephalomyelitis produced actively by injection of central nervous system antigens in complete Freund’s adjuvants. C
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 36:488-498
An attempt has been made to develop a model of chronic experimental allergic neuritis (EAN) using juvenile and adult inbred (Strain 13) and Hartley guinea pigs sensitized with peripheral nerve in complete Freund's adjuvant. Animals were followed clin
Publikováno v:
Journal of the Neurological Sciences. 41:17-29
Groups of juvenile Strain 13 guinea pigs sensitized for chronic relapsing experimental allergic encephalomyelitis (EAE) with isogeneic central nervous system (CNS) tissue in complete Freund's adjuvant (CFA) were either left to develop late-onset chro
Publikováno v:
The Journal of Immunology. 117:1159-1163
Inbred strain 2 and random-bred guinea pigs injected with oxazolone in incomplete or complete Freund's adjuvant showed contact reactions within an hour after topical application when tested 3 weeks post-sensitization. The time for appearance of skin
Publikováno v:
Journal of the Neurological Sciences. 56:65-73
Preliminary results are presented on the treatment of Strain 13 guinea pigs with chronic relapsing experimental autoimmune (allergic) encephalomyelitis (EAE) induced by a single sensitisation with whole spinal cord. Animals were treated at different
Publikováno v:
Cellular Immunology. 68:261-275
Using a monoclonal antibody against guinea pig T cells and anti-guinea pig immunoglobulins, T- and B-cell dynamics were studied by immunofluorescence in situ in the central nervous system (CNS) of animals with untreated and treated chronic relapsing
Publikováno v:
Science. 201:445-448
The expression of chronic relapsing experimental allergic encephalomyelitis in strain 13 guinea pigs was suppressed with a single series of injections of myelin basic protein in incomplete Freund's adjuvant. The suppression appeared permanent, and su
Publikováno v:
Acta Neuropathologica. 43:43-53
Central nervous system (CNS) lesion morphology has been studied in inbred Strain 13 guinea pigs sensitized for chronic relapsing EAE in which the disease was either left to develop (unsuppressed) or was suppressed with injections containing myelin ba