Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sanford C. Bledsoe"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Calcitonin-gene-related peptide (CGRP) is a lateral olivocochlear (LOC) efferent neurotransmitter. Depression of sound-driven auditory brainstem response amplitude in CGRP-null mice suggests the potential for endogenous CGRP release to upregulate spo
Externí odkaz:
https://doaj.org/article/da331045411241ee9f706217ac1aa598
Publikováno v:
Neuroscience Letters. 571:17-22
Dynorphin (dyn) is suggested to excite the auditory nerve (AN) when released by the lateral olivocochlear (LOC) efferents. However, previous studies evaluated either intravenously delivered dyn-like agents, raising the potential for systemic (central
Publikováno v:
The Journal of Neuroscience. 32:15791-15801
The cochlear nucleus (CN) receives innervation from auditory and somatosensory structures, which can be identified using vesicular glutamate transporters, VGLUT1 and VGLUT2. VGLUT1 is highly expressed in the magnocellular ventral CN (VCN), which rece
Publikováno v:
The Journal of Neuroscience. 32:1660-1671
The dorsal cochlear nucleus (DCN) is the first neural site of bimodal auditory-somatosensory integration. Previous studies have shown that stimulation of somatosensory pathways results in immediate suppression or enhancement of subsequent acousticall
Autor:
Sanford C. Bledsoe, Richard A. Altschuler, Josef M. Miller, Susan DeRemer, Diane M. Prieskorn, Cathy Martin, Noel L. Wys
Publikováno v:
Scientific Reports
Noise overstimulation can induce loss of synaptic ribbons associated with loss of Inner Hair Cell – Auditory Nerve synaptic connections. This study examined if systemic administration of Piribedil, a dopamine agonist that reduces the sound evoked a
Publikováno v:
Journal of Microelectromechanical Systems. 15:1025-1033
This paper describes the development of shutters, fluidic ribbon cables, and flowmeters for use on bulk-micromachined neural probes. The resulting devices permit electrical recording, stimulation, and chemical drug delivery in the central nervous sys
Publikováno v:
Journal of Micromechanics and Microengineering. 14:957-968
A study was conducted to measure and characterize the reliability of polysilicon cantilever beams with electroplated gold pads for use in a high-density biomedical connector. In this design, an array of beams is brought into contact with a correspond
Publikováno v:
Experimental Brain Research. 153:427-435
The cochlear nucleus (CN) commissural connection represents the first opportunity for convergence of binaural information in the auditory brainstem. All major neuron types in the ventral CN (VCN) are innervated by a diverse population of cells in the
Autor:
Colleen G. Le Prell, Larry F. Hughes, Sanford C. Bledsoe, Richard A. Altschuler, David F. Dolan, Susan E. Shore
Publikováno v:
Neuroscience letters. 582
Neurons of the lateral olivocochlear (LOC) system project from the auditory brainstem to the cochlea, where they synapse on radial dendrites of auditory nerve fibers. Selective LOC disruption depresses sound-evoked auditory nerve activity in the guin
Publikováno v:
NeuroReport. 7:225-229
Studies in rats and guinea pigs indicate that local changes in inhibitory transmitters may underlie deafness-induced plastic changes in electrophysiological responsiveness of cells of the mature central auditory system. Following 21 days of bilateral