Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sandy Y. Chang"'
Autor:
Sandy Y. Chang, Sarah E. Hudon-Miller, Shao H. Yang, Hea-Jin Jung, John M. Lee, Emily Farber, Thangaiah Subramanian, Douglas A. Andres, H.Peter Spielmann, Christine A. Hrycyna, Stephen G. Young, Loren G. Fong
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 6, Pp 1176-1182 (2012)
Protein farnesyltransferase (FTase) inhibitors, generally called “FTIs,” block the farnesylation of prelamin A, inhibiting the biogenesis of mature lamin A and leading to an accumulation of prelamin A within cells. A recent report found that a GG
Externí odkaz:
https://doaj.org/article/fa11a5ebf9b14cd18d47c42842a004d2
Autor:
Shao H. Yang, Sandy Y. Chang, Yiping Tu, Gregory W. Lawson, Martin O. Bergo, Loren G. Fong, Stephen G. Young
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 1, Pp 77-86 (2012)
Protein farnesyltransferase (FTase) and protein geranylgeranyltransferase-I (GGTase-I) add 15- or 20-carbon lipids, respectively, to proteins that terminate with a CaaX motif. These posttranslational modifications of proteins with lipids promote prot
Externí odkaz:
https://doaj.org/article/6f7025107a9b4162a7fc44d2ff69af33
Autor:
Shao H. Yang, Sandy Y. Chang, Douglas A. Andres, H. Peter Spielmann, Stephen G. Young, Loren G. Fong
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 2, Pp 400-405 (2010)
Hutchinson-Gilford progeria syndrome (HGPS) is caused by the accumulation of a farnesylated form of prelamin A (progerin). Previously, we showed that blocking protein farnesylation with a farnesyltransferase inhibitor (FTI) ameliorates the disease ph
Externí odkaz:
https://doaj.org/article/e784bf73496b4598b7c6c0d27291cbf9
Autor:
Sandy Y, Chang, Carlos A Q, Santos
Publikováno v:
Transplant Infectious Disease. 24
Antimicrobial stewardship in solid organ transplant (SOT) recipients is important to prevent antimicrobial-associated complications, but traditional stewardship principles are challenging to implement for SOT patients. Newer methodologies to optimize
Autor:
Sandy Y. Chang, Travis K. Price, Omer E. Beaird, Pryce T. Gaynor, Joanna M. Schaenman, Margrit E. Carlson, Bernard M. Kubak, Shangxin Yang, Ashrit Multani
Publikováno v:
Transplant infectious disease : an official journal of the Transplantation Society, vol 24, iss 3
BackgroundMycoplasma hominis can cause significant infections after solid organ transplantation (SOT). Treatment should be guided by susceptibility testing, but conventional lab methods are laborious with prolonged turnaround time (TAT). This case se
Autor:
Sandy Y. Chang, Karolina Faysman, Anjali Bisht, Daniel Z. Uslan, Gary J. Schiller, Ashrit Multani
Publikováno v:
Open Forum Infectious Diseases
Open forum infectious diseases, vol 8, iss 8
Open forum infectious diseases, vol 8, iss 8
Measles is a worldwide viral disease that can cause fatal complications in immunocompromised hosts such as hematopoietic cell transplant (HCT) recipients. The live attenuated measles, mumps, and rubella (MMR) vaccine is generally contraindicated post
Publikováno v:
Medical mycology. 59(9)
Coccidioidal meningitis (CM) is a life-threatening infection with limited treatment options. Small series have reported success with isavuconazole; however, limited data exist on cerebrospinal fluid (CSF) penetration. Paired plasma and CSF isavuconaz
Autor:
Norma P. Sandoval, Tiffany Ly P. Dang, Anne P. Beigneux, Loren G. Fong, Katsuyuki Nakajima, Michael Ploug, Isamu Fukamachi, G. Kees Hovingh, Stephen G. Young, Xuchen Hu, Geesje M. Dallinga-Thie, Masami Murakami, Kazuya Miyashita, Sandy Y. Chang
Publikováno v:
Journal of Clinical Lipidology. 11:964-971
Background GPIHBP1, a glycolipid-anchored protein of capillary endothelial cells, binds lipoprotein lipase (LPL) in the interstitial spaces and transports it to the capillary lumen. GPIHBP1 deficiency prevents LPL from reaching the capillary lumen, r
Autor:
Christopher J. Graber, Roswell Quinn, Sandy Y. Chang, Holly Wilhalme, Kristin Schwab, Jessica Howard-Anderson
Publikováno v:
Diagnosis (Berlin, Germany), vol 6, iss 2
Diagnosis (Berl)
Diagnosis (Berl)
Background Scant data exists to guide the work-up for fever in hospitalized patients, and little is known about what diagnostic tests medicine residents order for such patients. We sought to analyze how cross-covering medicine residents address fever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5446e3f37ee298a1287ecb3f4f97b071
https://escholarship.org/uc/item/30m630kn
https://escholarship.org/uc/item/30m630kn
Autor:
Sandy Y. Chang, Yiping Tu, Loren G. Fong, Shao H. Yang, Stephen G. Young, Gregory W. Lawson, Martin O. Bergo
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 1, Pp 77-86 (2012)
Protein farnesyltransferase (FTase) and protein geranylgeranyltransferase-I (GGTase-I) add 15- or 20-carbon lipids, respectively, to proteins that terminate with a CaaX motif. These posttranslational modifications of proteins with lipids promote prot