Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sandy T Baker"'
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152027 (2016)
The in vivo ovine model provides a clinically relevant platform to study cardiopulmonary mechanisms and treatments of disease; however, a robust ovine primary alveolar epithelial type II (ATII) cell culture model is lacking. The objective of this stu
Externí odkaz:
https://doaj.org/article/f553d0e45c1e4206a363ba20c8115e3d
Autor:
Marla R. Wolfson, Wolfgang F. Graier, Peter P. Rainer, Ying H. Lin, Timothy A. McKinsey, Jessica Pfleger, Sadia Mohsin, Jichuan Wu, Deborah M Eaton, Sandy T. Baker, Juergen Gindlhuber, Giulia Borghetti, Matthias Schittmayer, Mark Y. Jeong, Laura Liesinger, Sandra Blass, Andreas Zirlik, Huaqing Zhao, Steven R. Houser, Remus M. Berretta, Ruth Birner-Gruenberger, Markus Wallner, Dirk von Lewinski, Heiko Bugger
Publikováno v:
Sci Transl Med
Heart failure with preserved ejection fraction (HFpEF) is a major health problem without effective therapies. This study assessed the effects of histone deacetylase (HDAC) inhibition on cardiopulmonary structure, function, and metabolism in a large m
Autor:
Mark A. Oyama, Dirk von Lewinski, Sadia Mohsin, Christoph Magnes, Timothy A. McKinsey, Jichuan Wu, Giulia Borghetti, Peter P. Rainer, Natalie Bordag, Heiner Post, Markus Wallner, Mark Y. Jeong, Marla R. Wolfson, Remus M. Berretta, Ying H Lin, Sandy T. Baker, Steven R. Houser, Elmar Zügner, Deborah M Eaton, Huaqing Zhao
Publikováno v:
Circulation Research. 125
Rationale: Approximately 50% of heart failure patients are diagnosed with Heart Failure with preserved Ejection Fraction (HFpEF), but there are currently no effective treatments. Hypothesis: Treatment of a feline HFpEF animal model with a pan HDAC in
Autor:
Jeffrey N. Weiser, Yong Li, Peggy Zhang, Ying Tian, Yan Wang, Marla R. Wolfson, Hao Shen, Sandy T. Baker
Bacterial pneumonia remains a leading cause of morbidity and mortality worldwide. A defining feature of pneumonia is lung injury, leading to protracted suffering and vulnerability long after bacterial clearance. Little is known about which cells are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615e3fa37d7162606513274223ff1357
https://europepmc.org/articles/PMC6486708/
https://europepmc.org/articles/PMC6486708/
Autor:
Steven R. Houser, Timothy A. McKinsey, Mark A. Oyama, Deborah M Eaton, Markus Wallner, Marla R. Wolfson, Sandy T. Baker, Sadia Mohsin, Dirk von Lewinski, Jichuan Wu, Ying Lin, Heiner Post, Mark Y. Jeong, Remus M. Berretta
Publikováno v:
Circulation Research. 123
Rationale: Heart Failure with preserved Ejection Fraction (HFpEF) accounts for about 50% of all heart failure cases but has no effective therapies. Hypothesis: Inhibition of histone deacetylase (HDAC) catalytic activity exerts beneficial effects on t
Autor:
Timothy A. McKinsey, Ying H Lin, Steve R. Houser, Mark Y. Jeong, Marla R. Wolfson, Deborah M Eaton, D Von Lewinski, Remus M. Berretta, Sandy T. Baker, Markus Wallner, Mark A. Oyama, Sadia Mohsin, Jichuan Wu
Publikováno v:
European Heart Journal. 39
Autor:
Michael W. Weaver, Kadir Erkmen, Gennaro Calendo, Marla R. Wolfson, Sandy T. Baker, Mustafa Yavuz Samanci
Publikováno v:
World neurosurgery. 121
Objective Subarachnoid hemorrhage (SAH) frequently results in severe morbidity, even mortality. Hypothermia is known to have a neuroprotective effect in ischemic injuries. The aim of this study was to determine whether nasopharyngeal (NP) perfluoroch
Autor:
Giulia Borghetti, Mark A. Oyama, Deborah M Eaton, Sadia Mohsin, Thomas E. Sharp, Jichuan Wu, Sandy T. Baker, Remus M. Berretta, Dirk von Lewinski, Markus Wallner, Marla R. Wolfson, Eric Feldsott, Steven R. Houser, Heiner Post
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Heart Failure with preserved Ejection Fraction (HFpEF) represents a major public health problem. The causative mechanisms are multifactorial and there are no effective treatments for HFpEF, partially attributable to the lack of well-established HFpEF
Autor:
Matthew Kauffman, Paul A. Kennedy, Jichuan Wu, Linda C. Knight, Sandy T. Baker, Marla R. Wolfson, Laurie E. Kilpatrick, Mark J. Mondrinos
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 355:86-98
Sepsis and sepsis-induced lung injury remain a leading cause of death in intensive care units. We identified protein kinase C-δ (PKCδ) as a critical regulator of the acute inflammatory response and demonstrated that PKCδ inhibition was lung-protec
Autor:
T.E. Sharp, Jichuan Wu, Mark A. Oyama, M. Wallner, Deborah M Eaton, Steve R. Houser, P.R. Fox, Marla R. Wolfson, Remus M. Berretta, C.D. Troupes, Sandy T. Baker, G. Borghetti, E.A. Feldsott
Publikováno v:
European Heart Journal. 38