Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sandy S. Burkart"'
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-10 (2022)
Abstract Properly responding to DNA damage is vital for eukaryotic cells, including the induction of DNA repair, growth arrest and, as a last resort to prevent neoplastic transformation, cell death. Besides being crucial for ensuring homeostasis, the
Externí odkaz:
https://doaj.org/article/0c687c3a76444845bafb869c4b7def0a
Autor:
Christopher J. Neufeldt, Berati Cerikan, Mirko Cortese, Jamie Frankish, Ji-Young Lee, Agnieszka Plociennikowska, Florian Heigwer, Vibhu Prasad, Sebastian Joecks, Sandy S. Burkart, David Y. Zander, Baskaran Subramanian, Rayomand Gimi, Seetharamaiyer Padmanabhan, Radhakrishnan Iyer, Mathieu Gendarme, Bachir El Debs, Niels Halama, Uta Merle, Michael Boutros, Marco Binder, Ralf Bartenschlager
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Neufeldt et al. evaluate transcriptional and cytokine secretion profiles of cells and patient sera following SARS-CoV-2 infection and detect distinct upregulation of inflammatory cytokines. They also demonstrate that this upregulation is mediated by
Externí odkaz:
https://doaj.org/article/e74d2975b29b4848bc2c7e84d04fd670
Autor:
Vladimir G. Magalhães, Sören Lukassen, Maike Drechsler, Jennifer Loske, Sandy S. Burkart, Sandra Wüst, Eva-Maria Jacobsen, Jobst Röhmel, Marcus A. Mall, Klaus-Michael Debatin, Roland Eils, Stella Autenrieth, Aleš Janda, Irina Lehmann, Marco Binder
To cope with novel virus infections to which no prior adaptive immunity exists, the body strongly relies on the innate immune system. In such cases, including infections with SARS-CoV-2, children tend to fair better than adults. In the context of COV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c77e4fed6b9d3acc85255cc93877d01
https://doi.org/10.1101/2023.05.17.541103
https://doi.org/10.1101/2023.05.17.541103
Autor:
Sandy S. Burkart, Darius Schweinoch, Jamie Frankish, Carola Sparn, Sandra Wüst, Christian Urban, Antonio Piras, Andreas Pichlmair, Joschka Willemsen, Lars Kaderali, Marco Binder
The pattern recognition receptor RIG-I is essential for the recognition of viral dsRNA and the activation of a cell-autonomous antiviral response. Upon stimulation, RIG-I triggers a signaling cascade leading to the expression of cytokines, most promi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0b4ff0e69536e94778b25f496871310
https://doi.org/10.1101/2022.08.05.502818
https://doi.org/10.1101/2022.08.05.502818
Properly responding to DNA damage is vital for eukaryotic cells, including the induction of DNA repair, growth arrest and, as a last resort to prevent neoplastic transformation, cell death. Besides being crucial for ensuring homeostasis, the same pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb82d5c11d2d7b5d237129ceec7ea054
https://doi.org/10.1101/2021.10.21.465312
https://doi.org/10.1101/2021.10.21.465312
Autor:
Birgit Kemmerling, Karl Heinz Braun, Anne-Flore Deroubaix, Julien Gronnier, Julia Mergner, Véronique Germain, Corinna A. Buschle, Paul Derbyshire, Sandy S. Burkart, Bernhard Kuester, Sébastien Mongrand, Jessica Folgmann, Macarena Marín, Frank L.H. Menke, Casandra Hernandez-Ryes, Nikolaj B. Abel, Iris K. Jarsch, Emmanuelle Bayer, Thomas Ott, Cyril Zipfel
Plant growth and development are modulated by both biotic and abiotic stress. Increasing evidence suggests that cellular integration of the corresponding signals occurs within preformed hubs at the plasma membrane called nanodomains. These membrane s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06d96a3432a0d392f5fa8e8edb4fa962
https://doi.org/10.1101/2021.01.28.428596
https://doi.org/10.1101/2021.01.28.428596
Autor:
Berati Cerikan, Sebastian Joecks, Ji-Young Lee, Mirko Cortese, Sandy S Burkart, Ralf Bartenschlager, Bachir El Debs, Marco Binder, Agnieszka Plociennikowska, Uta Merle, Michael Boutros, Christopher J. Neufeldt, Florian Heigwer, Jamie Frankish, Mathieu Gendarme, Niels Halama, David Yves Zander
SARS-CoV-2 is a novel virus that has rapidly spread, causing a global pandemic. In the majority of infected patients, SARS-CoV-2 leads to mild disease; however, in a significant proportion of infections, individuals develop severe symptoms that can l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e16f1b6dfbc52032a26eb137ba4bfa
https://doi.org/10.1101/2020.07.21.212639
https://doi.org/10.1101/2020.07.21.212639
Publikováno v:
Cells
Cells, Vol 10, Iss 2600, p 2600 (2021)
Volume 10
Issue 10
Cells, Vol 10, Iss 2600, p 2600 (2021)
Volume 10
Issue 10
Host cell-intrinsic antiviral responses are largely mediated by pattern-recognition receptor (PRR) signaling and the interferon (IFN) system. The IFN regulatory factor (IRF) family of transcription factors takes up a central role in transcriptional r
Autor:
Wüst S; Research Group 'Dynamics of Viral Infection and the Innate Antiviral Response', Division F170, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Schad P; Research Group 'Dynamics of Viral Infection and the Innate Antiviral Response', Division F170, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany., Burkart S; Research Group 'Dynamics of Viral Infection and the Innate Antiviral Response', Division F170, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, 69120 Heidelberg, Germany., Binder M; Research Group 'Dynamics of Viral Infection and the Innate Antiviral Response', Division F170, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Publikováno v:
Cells [Cells] 2021 Sep 30; Vol. 10 (10). Date of Electronic Publication: 2021 Sep 30.