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Autor:
Abdullah Kherzai, Zhebo Chen, Larry Solomon, Don J. Davidson, Earl F. Gubbins, Rick Lesniewski, David A. Egan, Sandy Majest, Karl A. Walter, Catherine J. Haskell, Schneider Andrew J, Jack Henkin
Publikováno v:
Cancer research. 65(11)
Kringle 5 (K5) of human plasminogen has been shown to inhibit angiogenesis by inducing the apoptosis of proliferating endothelial cells. Peptide regions around the lysine-binding pocket of K5 largely mediate these effects, particularly the peptide PR