Výsledky vyhledávání - "Sandy Liddell"

A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer

Autor: Philip Beale, Stephen Clarke, Peter Tobin, Laurent P. Rivory, Leesa Noney, Sandy Liddell

Publikováno v: Cancer Chemotherapy and Pharmacology. 57:309-316

Purpose: Recently, it was shown that chrysin causes upregulation of UGT1A1 in Caco-2 intestinal cells. Therefore, we proposed that oral chrysin may reduce irinotecan (CPT-11) induced diarrhoea by shifting the SN-38G/SN-38 equilibrium towards the inac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864ddc00272f4746a01edad754cd90d9
https://doi.org/10.1007/s00280-005-0053-0

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