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pro vyhledávání: '"Sandy Che-Eun Lee"'
Autor:
K. H. Brian Lam, Alberto J. Leon, Weili Hui, Sandy Che-Eun Lee, Ihor Batruch, Kevin Faust, Almos Klekner, Gábor Hutóczki, Marianne Koritzinsky, Maxime Richer, Ugljesa Djuric, Phedias Diamandis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Gioblastoma tumours consist of different niches defined by histology. Here, the authors use proteomics and machine learning to assign protein expression programs to these niches, and reveal that KRAS and hypoxia are associated with drug resistance.
Externí odkaz:
https://doaj.org/article/247ebc3f13744c4b98c1b4e41d550bef
Autor:
K. H. Brian Lam, Alberto J. Leon, Weili Hui, Sandy Che-Eun Lee, Ihor Batruch, Kevin Faust, Almos Klekner, Gábor Hutóczki, Marianne Koritzinsky, Maxime Richer, Ugljesa Djuric, Phedias Diamandis
Publikováno v:
Nature Communications
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Glioblastoma is an aggressive form of brain cancer with well-established patterns of intra-tumoral heterogeneity implicated in treatment resistance and progression. While regional and single cell transcriptomic variations of glioblastoma have been re