Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sandy Blin"'
Autor:
Florian Ullrich, Sandy Blin, Katina Lazarow, Tony Daubitz, Jens Peter von Kries, Thomas J Jentsch
Publikováno v:
eLife, Vol 8 (2019)
Acid-sensing ion channels have important functions in physiology and pathology, but the molecular composition of acid-activated chloride channels had remained unclear. We now used a genome-wide siRNA screen to molecularly identify the widely expresse
Externí odkaz:
https://doaj.org/article/b4e93c9d6cbd4a358027e742c7171744
Autor:
Ismail Ben Soussia, Frank S. Choveau, Sandy Blin, Eun-Jin Kim, Sylvain Feliciangeli, Franck C. Chatelain, Dawon Kang, Delphine Bichet, Florian Lesage
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
TREK/TRAAK channels are polymodal K+ channels that convert very diverse stimuli, including bioactive lipids, mechanical stretch and temperature, into electrical signals. The nature of the structural changes that regulate their activity remains an ope
Externí odkaz:
https://doaj.org/article/67683d0d8ef84390be2c9f1f6e496be8
Autor:
Sylvain Feliciangeli, Ismail Ben Soussia, Franck C. Chatelain, Frank S. Choveau, Eun-Jin Kim, Delphine Bichet, Sandy Blin, Florian Lesage, Dawon Kang
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Frontiers Media, 2018, 11, ⟨10.3389/fnmol.2018.00301⟩
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience, Frontiers Media, 2018, 11, ⟨10.3389/fnmol.2018.00301⟩
Frontiers in Molecular Neuroscience, Vol 11 (2018)
TREK/TRAAK channels are polymodal K+ channels that convert very diverse stimuli, including bioactive lipids, mechanical stretch and temperature, into electrical signals. The nature of the structural changes that regulate their activity remains an ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19cdddf4d48ac47edd6398647bbb888a
https://hal.archives-ouvertes.fr/hal-03095023
https://hal.archives-ouvertes.fr/hal-03095023
Autor:
Delphine Bichet, Dawon Kang, Florian Lesage, Ismail Ben Soussia, Eun-Jin Kim, Sandy Blin, Frédéric Brau
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (15), pp.4200-4205. ⟨10.1073/pnas.1522748113⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (15), pp.4200-4205. ⟨10.1073/pnas.1522748113⟩
The tandem of pore domain in a weak inwardly rectifying K(+) channel (Twik)-related acid-arachidonic activated K(+) channel (TRAAK) and Twik-related K(+) channels (TREK) 1 and TREK2 are active as homodimers gated by stretch, fatty acids, pH, and G pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a5b600382a8ddb0fe417421231da7b
https://hal.archives-ouvertes.fr/hal-03094985
https://hal.archives-ouvertes.fr/hal-03094985
Silent but not dumb: how cellular trafficking and pore gating modulate expression of TWIK1 and THIK2
Autor:
Nicole Bobak, Sylvain Feliciangeli, Sandy Blin, Franck C. Chatelain, Delphine Bichet, Florian Lesage
Publikováno v:
Pflügers Archiv European Journal of Physiology
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2015, 467 (5), pp.1121-1131. ⟨10.1007/s00424-014-1631-y⟩
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2015, 467 (5), pp.1121-1131. ⟨10.1007/s00424-014-1631-y⟩
Among K2P channels, a few of them turned out to be difficult to express in heterologous systems and were coined "silent subunits". Recent studies have shed light on the mechanisms behind this apparent lack of channel activity at the plasma membrane.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ade20e4fd5a53e54e18c06b2b42d375
https://hal.archives-ouvertes.fr/hal-02390419
https://hal.archives-ouvertes.fr/hal-02390419
Autor:
Franck C. Chatelain, Florian Lesage, Delphine Bichet, Sylvain Feliciangeli, Sandy Blin, Dawon Kang
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (41), pp.28202-28212. ⟨10.1074/jbc.M114.600437⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (41), pp.28202-28212. ⟨10.1074/jbc.M114.600437⟩
Despite a high level of sequence homology, tandem pore domain halothane-inhibited K(+) channel 1 (THIK1) produces background K(+) currents, whereas THIK2 is silent. This lack of activity is due to a unique combination of intracellular retention and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244257efe85b819a0a67e6a90683c6bf
https://hal.archives-ouvertes.fr/hal-02390421
https://hal.archives-ouvertes.fr/hal-02390421
Publikováno v:
Nature Cell Biology
Intracellular organelles change their size during trafficking and maturation. This requires the transport of ions and water across their membranes. Macropinocytosis, a ubiquitous form of endocytosis of particular importance for immune and cancer cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7474d40cdf9430275a2c84d7f60b586