Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sandy, Figiel"'
Autor:
Trishna A. Desai, Åsa K. Hedman, Marios Dimitriou, Mine Koprulu, Sandy Figiel, Wencheng Yin, Mattias Johansson, Eleanor L. Watts, Joshua R. Atkins, Aleksandr V. Sokolov, Helgi B. Schiöth, Marc J. Gunter, Konstantinos K. Tsilidis, Richard M. Martin, Maik Pietzner, Claudia Langenberg, Ian G. Mills, Alastair D. Lamb, Anders Mälarstig, Tim J. Key, Ruth C. Travis, Karl Smith-Byrne
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105168- (2024)
Summary: Background: Understanding the role of circulating proteins in prostate cancer risk can reveal key biological pathways and identify novel targets for cancer prevention. Methods: We investigated the association of 2002 genetically predicted ci
Externí odkaz:
https://doaj.org/article/1ace1755f8ce4d638c80b4c3f3d25968
Autor:
Marion Papin, Delphine Fontaine, Caroline Goupille, Sandy Figiel, Isabelle Domingo, Michelle Pinault, Cyrille Guimaraes, Nina Guyon, Pierre François Cartron, Patrick Emond, Antoine Lefevre, Maxime Gueguinou, David Crottès, Paul-Alain Jaffrès, Lobna Ouldamer, Karine Maheo, Gaëlle Fromont, Marie Potier-Cartereau, Philippe Bougnoux, Aurélie Chantôme, Christophe Vandier
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 5, Pp 100544- (2024)
SK3 channels are potassium channels found to promote tumor aggressiveness. We have previously demonstrated that SK3 is regulated by synthetic ether lipids, but the role of endogenous ether lipids is unknown. Here, we have studied the role of endogeno
Externí odkaz:
https://doaj.org/article/c60252b33184451bac3e20c91baf77d9
Autor:
Sandy Figiel, Géraldine Cancel-Tassin, Ian G. Mills, Alastair D. Lamb, Gaelle Fromont, Olivier Cussenot
Publikováno v:
Anatomia, Vol 2, Iss 4, Pp 300-319 (2023)
Understanding prostate carcinogenesis is crucial not only for identifying new treatment targets but also for developing effective strategies to manage the asymptomatic form of the disease. There is a lack of consensus about predicting the indolent fo
Externí odkaz:
https://doaj.org/article/30fd491ddfdc423390dae3dcfb369410
Autor:
Sandy Figiel, Wencheng Yin, Dimitrios Doultsinos, Andrew Erickson, Ninu Poulose, Reema Singh, Anette Magnussen, Thineskrishna Anbarasan, Renuka Teague, Mengxiao He, Joakim Lundeberg, Massimo Loda, Clare Verrill, Richard Colling, Pelvender S. Gill, Richard J. Bryant, Freddie C. Hamdy, Dan J. Woodcock, Ian G. Mills, Olivier Cussenot, Alastair D. Lamb
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-5 (2023)
Abstract Genetic signatures have added a molecular dimension to prognostics and therapeutic decision-making. However, tumour heterogeneity in prostate cancer and current sampling methods could confound accurate assessment. Based on previously publish
Externí odkaz:
https://doaj.org/article/586aa75e487c4ec0a28a445500a1ab30
Autor:
Delphine Fontaine, Sandy Figiel, Romain Félix, Sana Kouba, Gaëlle Fromont, Karine Mahéo, Marie Potier-Cartereau, Aurélie Chantôme, Christophe Vandier
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 6, Pp 840-858 (2020)
Ether lipids (ELs) are lipids characterized by the presence of either an ether linkage (alkyl lipids) or a vinyl ether linkage [i.e., plasmalogens (Pls)] at the sn1 position of the glycerol backbone, and they are enriched in PUFAs at the sn2 position
Externí odkaz:
https://doaj.org/article/16e50e30cc084062977e19ccaa8d3a36
Autor:
Sandy Figiel, Wencheng Yin, Dimitrios Doultsinos, Andrew Erickson, Ninu Poulose, Reema Singh, Anette Magnussen, Thineskrishna Anbarasan, Renuka Teague, Mengxiao He, Joakim Lundeberg, Massimo Loda, Clare Verrill, Richard Colling, Pelvender S. Gill, Richard J. Bryant, Freddie C. Hamdy, Dan J. Woodcock, Ian G. Mills, Olivier Cussenot, Alastair D. Lamb
Genetic signatures have added a molecular dimension to prognostics and therapeutic decision-making. However, tumour heterogeneity in prostate cancer and current sampling methods could confound accurate assessment. Based on previously published spatia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf9a0ff468476993cde7a3976e436256
https://doi.org/10.1101/2023.03.08.531491
https://doi.org/10.1101/2023.03.08.531491
Autor:
Marie Potier-Cartereau, Gaëlle Fromont, Côme Pasqualin, Karine Mahéo, Roseline Guibon, Fanny Bery, Franck Bruyère, Véronique Maupoil, Christophe Vandier, Sandy Figiel, Isabelle Domingo
Publikováno v:
The American Journal of Pathology. 189:1268-1275
In prostate cancer research, there is a lack of valuable preclinical models. Tumor cell heterogeneity and sensitivity to microenvironment signals, such as hypoxia or extracellular calcium concentration, are difficult to reproduce. Here, we developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d93cb2c6acc2a4cbc269fe39a973c54
https://doi.org/10.1016/j.ajpath.2019.02.017
https://doi.org/10.1016/j.ajpath.2019.02.017
Autor:
Fanny Bery, Sandy Figiel, Sana Kouba, Delphine Fontaine, Maxime Guéguinou, Marie Potier-Cartereau, Christophe Vandier, Roseline Guibon, Franck Bruyère, Gaëlle Fromont, Karine Mahéo
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 4786, p 4786 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 4786, p 4786 (2020)
Hypoxia is a well-established feature of prostate cancer (PCa) and is associated with disease aggressiveness. The hypoxic microenvironment initiates multiple adaptive responses including epithelial-to-mesenchymal transition (EMT) and a remodeling of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c997292389f53d5b9f74bc54797350cc
http://europepmc.org/articles/PMC7369999
http://europepmc.org/articles/PMC7369999
Publikováno v:
Human Pathology. 61:26-32
The process of epithelial-to-mesenchymal transition (EMT) contributes to cancer progression, with activation of transcription factors leading to loss of epithelial characteristics and acquirement of mesenchymal properties. We analyzed in human prosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14b49811bc189dbd6050da4cddc108e
https://doi.org/10.1016/j.humpath.2016.10.013
https://doi.org/10.1016/j.humpath.2016.10.013
Autor:
Sandy, Figiel, Côme, Pasqualin, Fanny, Bery, Veronique, Maupoil, Christophe, Vandier, Marie, Potier-Cartereau, Isabelle, Domingo, Roseline, Guibon, Franck, Bruyere, Karine, Maheo, Gaelle, Fromont
Publikováno v:
American Journal of Pathology
American Journal of Pathology, 2019, 189 (6), pp.1268-1275. ⟨10.1016/j.ajpath.2019.02.017⟩
American Journal of Pathology, American Society for Investigative Pathology, 2019, 189 (6), pp.1268-1275. ⟨10.1016/j.ajpath.2019.02.017⟩
American Journal of Pathology, 2019, 189 (6), pp.1268-1275. ⟨10.1016/j.ajpath.2019.02.017⟩
American Journal of Pathology, American Society for Investigative Pathology, 2019, 189 (6), pp.1268-1275. ⟨10.1016/j.ajpath.2019.02.017⟩
International audience; In prostate cancer research, there is a lack of valuable preclinical models. Tumor cell heterogeneity and sensitivity to microenvironment signals, such as hypoxia or extracellular calcium concentration, are difficult to reprod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::20c7e5248924a5e95f09b1730be3705a
https://hal.science/hal-02460711/document
https://hal.science/hal-02460711/document