Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Sandro Silva-Gomes"'
1
Akademický článek
Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis
Autor: Tiago L. Duarte, Carolina Caldas, Ana G. Santos, Sandro Silva-Gomes, Andreia Santos-Gonçalves, Maria João Martins, Graça Porto, José Manuel Lopes
Publikováno v: Redox Biology, Vol 11, Iss , Pp 157-169 (2017)
Background and Aims: In hereditary hemochromatosis, iron deposition in the liver parenchyma may lead to fibrosis, cirrhosis and hepatocellular carcinoma. Most cases are ascribed to a common mutation in the HFE gene, but the extent of clinical express
Externí odkaz: https://doaj.org/article/da0e2e6188554f3d9b7b340b445adfa1
Zobrazit plný text záznamu
2
Akademický článek
Assessment of Protocol Impact on Subjectivity Uncertainty When Analyzing Peripheral Blood Mononuclear Cell Flow Cytometry Data Files
Autor: Rebecca Grant, Karen Coopman, Sandro Silva-Gomes, Jonathan J. Campbell, Bo Kara, Julian Braybrook, Jon Petzing
Publikováno v: Methods and Protocols, Vol 4, Iss 2, p 24 (2021)
Measured variability of product within Cell and Gene Therapy (CGT) manufacturing arises from numerous sources across pre-analytical to post-analytical phases of testing. Operators are a function of the manufacturing process and are an important sourc
Externí odkaz: https://doaj.org/article/ea948a785baf45848f1387ff700a1777
Zobrazit plný text záznamu
3
Akademický článek
Mycobacterium avium infection induces H-ferritin expression in mouse primary macrophages by activating Toll-like receptor 2.
Autor: Sandro Silva-Gomes, Cécile Bouton, Tânia Silva, Paolo Santambrogio, Pedro Rodrigues, Rui Appelberg, Maria Salomé Gomes
Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82874 (2013)
Important for both host and pathogen survivals, iron is a key factor in determining the outcome of an infectious process. Iron with-holding, including sequestration inside tissue macrophages, is considered an important strategy to fight infection. Ho
Externí odkaz: https://doaj.org/article/b966aba8a26c433a85c46e0965d7099e
Zobrazit plný text záznamu
4
Quantifying Operator Subjectivity within Flow Cytometry Data Analysis as a Source of Measurement Uncertainty and the Impact of Experience on Results
Autor: Nick Medcalf, Karen Coopman, Julian Braybrook, Jon N. Petzing, Bo Kara, Jonathan Campbell, Rebecca Grant, Sandro Silva-Gomes
Publikováno v: PDA Journal of Pharmaceutical Science and Technology. 75:33-47
Flow cytometry is a complex measurement characterization technique, utilized within the manufacture, measurement, and release of cell and gene therapy products for rapid, high-content, and multiplexed discriminatory cell analysis. A number of factors
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68e43629d61321a7c41f61b2dc0716d
https://doi.org/10.5731/pdajpst.2019.011213
Zobrazit plný text záznamu
5
Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis
Autor: Sandro Silva-Gomes, José Manuel Lopes, Graça Porto, Tiago L. Duarte, Carolina Caldas, Maria João Martins, Ana Gabriela Pires dos Santos, Andreia Santos-Gonçalves
Publikováno v: Redox Biology, Vol 11, Iss, Pp 157-169 (2017)
Redox Biology
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
Background and Aims In hereditary hemochromatosis, iron deposition in the liver parenchyma may lead to fibrosis, cirrhosis and hepatocellular carcinoma. Most cases are ascribed to a common mutation in the HFE gene, but the extent of clinical expressi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5feadec525059950078eecf58eaca5e2
http://www.sciencedirect.com/science/article/pii/S2213231716302749
Zobrazit plný text záznamu
6
Rational design of adjuvants targeting the C-type lectin Mincle
Autor: Eric Perouzel, Alain Vercellone, Jacques Prandi, Martine Gilleron, Sandro Silva-Gomes, David Sancho, Jérôme Nigou, Francisco J. Cueto, Gérard Tiraby, Thierry Lioux, Sophie Barbe, Alexiane Decout, Daniel Drocourt, Isabelle André
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (10), pp.2675-2680. ⟨10.1073/pnas.1612421114⟩
Proceedings of the National Academy of Sciences of the United States of America 10 (114), 2675-2680. (2017)
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (10), pp.2675-2680. ⟨10.1073/pnas.1612421114⟩
Adresse actuelle Decout Alexiane : GLYcoDiag, Res Dept, F-45067 Orléans 2, France; The advances in subunit vaccines development have intensified the search for potent adjuvants, particularly adjuvants inducing cell-mediated immune responses. Identif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56c225655bcba837d0dd6b0c3556392
https://doi.org/10.1073/pnas.1612421114
Zobrazit plný text záznamu
7
Assessment of Protocol Impact on Subjectivity Uncertainty When Analyzing Peripheral Blood Mononuclear Cell Flow Cytometry Data Files
Autor: Julian Braybrook, Jon N. Petzing, Bo Kara, Jonathan Campbell, Karen Coopman, Sandro Silva-Gomes, Rebecca Grant
Publikováno v: Methods and Protocols
Volume 4
Issue 2
Methods and Protocols, Vol 4, Iss 24, p 24 (2021)
Measured variability of product within Cell and Gene Therapy (CGT) manufacturing arises from numerous sources across pre-analytical to post-analytical phases of testing. Operators are a function of the manufacturing process and are an important sourc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff13d2c9bc39f26d4fdd0a75c9f7116d
https://doi.org/10.3390/mps4020024
Zobrazit plný text záznamu
8
Understanding the contribution of operator measurement variability within Flow Cytometry data analysis for Quality Control of Cell and Gene Therapy manufacturing
Autor: Julian Braybrook, Jon N. Petzing, Bo Kara, Nick Medcalf, Karen Coopman, Jonathan Campbell, Sandro Silva-Gomes, Rebecca Grant
Publikováno v: Measurement. 150:106998
Flow Cytometry is a measurement technique used in Quality Control and in-process measurements of biomanufactured Cell and Gene Therapy products. However, it contains a number of sources of measurement variation at; sample preparation, instrument setu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42a164c5eda5237da6df7b4687702761
https://doi.org/10.1016/j.measurement.2019.106998
Zobrazit plný text záznamu
9
Rational Design of Mannodendrimers Targeting Human C-type Lectin Receptors to Prevent Lung Inflammation
Autor: Alain Vercellone, Germain Puzo, Jérôme Nigou, Emilyne Blattes, Jacques Prandi, Sandro Silva-Gomes, Anne-Marie Caminade
Publikováno v: Phosphorus Dendrimers in Biology and Nanomedicine ISBN: 9781315110851
Phosphorus Dendrimers in Biology and Nanomedicine
Phosphorous Dendrimers in Biology and Nanomedicine: Syntheses, Characterization, and Properties
Caminade, A.-M. and Turrin, C.-O. and Majoral, J.-P. Phosphorous Dendrimers in Biology and Nanomedicine: Syntheses, Characterization, and Properties, 10, Pan Stanford Publishing, pp.265-285, 2018, 978-9-814-77433-8
International audience
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070401e64862f1ddd3e859d431ff792b
https://doi.org/10.1201/9781315110851-10
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje