Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sandro Sieber"'
Autor:
Patrick Hauswirth, Jonas Buck, Ramya Puligilla, Claudio Luca Alter, Sandro Sieber, Beatrice Claudi, Joseph Fanous, Dirk Bumann, Jörg Huwyler
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 5, p 99 (2023)
Introduction: Blood infections from multi-drug-resistant Salmonella pose a major health burden. This is especially true because Salmonella can survive and replicate intracellularly, and the development of new treatment strategies is dependent on expe
Externí odkaz:
https://doaj.org/article/0c7e1f50b348432794061c38b095f880
Autor:
Tomaž Einfalt, Martina Garni, Dominik Witzigmann, Sandro Sieber, Niklaus Baltisberger, Jörg Huwyler, Wolfgang Meier, Cornelia G. Palivan
Publikováno v:
Advanced Science, Vol 7, Iss 4, Pp n/a-n/a (2020)
Abstract Despite huge need in the medical domain and significant development efforts, artificial cells to date have limited composition and functionality. Although some artificial cells have proven successful for producing therapeutics or performing
Externí odkaz:
https://doaj.org/article/3202c7576d0d472881a5fabc1766209b
Autor:
Dominik Witzigmann, Philipp Uhl, Sandro Sieber, Christina Kaufman, Tomaz Einfalt, Katrin Schöneweis, Philip Grossen, Jonas Buck, Yi Ni, Susanne H Schenk, Janine Hussner, Henriette E Meyer zu Schwabedissen, Gabriela Québatte, Walter Mier, Stephan Urban, Jörg Huwyler
Publikováno v:
eLife, Vol 8 (2019)
Active targeting and specific drug delivery to parenchymal liver cells is a promising strategy to treat various liver disorders. Here, we modified synthetic lipid-based nanoparticles with targeting peptides derived from the hepatitis B virus large en
Externí odkaz:
https://doaj.org/article/06772f8c9ffb44f5b5c021716f8aad26
Autor:
Jörg Huwyler, Dirk Bumann, Joseph Fanous, Beatrice Claudi, Sandro Sieber, Claudio Luca Alter, Ramya Puligilla, Jonas Buck, Patrick Hauswirth
Publikováno v:
Frontiers in Bioscience-Landmark. 28:99
Autor:
Matthias Hamburger, Mouhssin Oufir, Daniel Ehrsam, Jörg Huwyler, Henriette E. Meyer zu Schwabedissen, Fabiola Porta, Sandro Sieber
Publikováno v:
Bioconjugate Chemistry. 31:781-793
The concept of triggered drug release offers a possibility to overcome the toxic side effects of chemotherapeutics in cancer treatment by reducing systemic exposure to the active drug. In the present work, the concept foresees the use of the extracel
Autor:
Sylvie Roke, Martina Konantz, Ali Yasin Sonay, Aysen Unsal, Ingo Lieberwirth, Claudia Lengerke, Shuai Jiang, Sandro Sieber, Katharina Landfester, Shahed Behzadi, Claire Teulon, Sine Yaganoglu, Konstantinos Kalyviotis, Periklis Pantazis, Daniel Crespy
Publikováno v:
ACS Nano
ACS Nano, 15 (3)
ACS Nano, 15 (3)
Optical imaging probes have played a major role in detecting and monitoring a variety of diseases. In particular, nonlinear optical imaging probes, such as second harmonic generating (SHG) nanoprobes, hold great promise as clinical contrast agents, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dde5a4413604881617787295bc86493
https://hdl.handle.net/21.11116/0000-0008-70C7-921.11116/0000-0008-70C9-7
https://hdl.handle.net/21.11116/0000-0008-70C7-921.11116/0000-0008-70C9-7
Autor:
Sandro Sieber, Jörg Huwyler, Mohamed Chami, Ioana Craciun, Andrea Belluati, Tomaz Einfalt, Juan Liu, Dominik Witzigmann, Dalin Wu, Cornelia G. Palivan
DNA has been widely used as a key tether to promote self-organization of super-assemblies with emergent properties. However, control of this process is still challenging for compartment assemblies and to date the resulting assemblies have unstable me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9152c4f237947b5eb0ff71a26773fe
https://edoc.unibas.ch/76575/
https://edoc.unibas.ch/76575/
Autor:
Matthias Barz, Jörg Huwyler, Christian Muhl, Regine Süss, Stefan Bleher, Sabine Barnert, Jonas Buck, Sandro Sieber, Dominik Witzigmann
Publikováno v:
SMALL, 15(50), 1904716. WILEY-V C H VERLAG GMBH
SMALL
SMALL
Circulation lifetime is a crucial parameter for a successful therapy with nanoparticles. Reduction and alteration of opsonization profiles by surface modification of nanoparticles is the main strategy to achieve this objective. In clinical settings,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c2099e717d12f326eb1eb36e191c57
https://hdl.handle.net/1887/3147120
https://hdl.handle.net/1887/3147120
Autor:
Cornelia G. Palivan, Adrian Najer, Tomaz Einfalt, Ozana Onaca-Fischer, Christoph Edlinger, Mariana Spulber, Dominik Witzigmann, Jörg Huwyler, Sandro Sieber, Roland Goers
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications, 9 (1)
Nature Communications
Nature Communications, 9 (1)
Nature Communications
Despite tremendous efforts to develop stimuli-responsive enzyme delivery systems, their efficacy has been mostly limited to in vitro applications. Here we introduce, by using an approach of combining biomolecules with artificial compartments, a biomi
Autor:
Sandro Sieber, Alexander Kros, Gabriela Arias-Alpizar, Frank L. Bos, Jörg Huwyler, Jeroen Bussmann, Frederick Campbell, Bjørn E. V. Koch
Publikováno v:
ACS Nano
ACS Nano, 12(3), 2138. American Chemical Society
ACS Nano, 12(3), 2138-2150
ACS Nano, 12(3), 2138. American Chemical Society
ACS Nano, 12(3), 2138-2150
Up to 99% of systemically administered nanoparticles are cleared through the liver. Within the liver, most nanoparticles are thought to be sequestered by macrophages (Kupffer cells), although significant nanoparticle interactions with other hepatic c