Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Sandro Ghisla"'
Autor:
Verena Peters, Marina Morath, Matthias Mack, Michael Liesert, Wolfgang Buckel, Georg F. Hoffmann, Jerry Vockley, Sandro Ghisla, Johannes Zschocke
Publikováno v:
JIMD Reports, Vol 47, Iss 1, Pp 30-34 (2019)
Abstract 3‐Hydroxyglutaric acid (3‐OH‐GA) in urine has been identified as the most reliable diagnostic marker for glutaric aciduria type I (GA I). We showed that hydratation of glutaconyl‐CoA to 3‐hydroxyglutaryl‐CoA, which is subsequentl
Externí odkaz:
https://doaj.org/article/3e6a1da4ce5c48c9a7d3e971aee1c4ef
Autor:
Cristiane Tavares, Thaís Maciel, Sandra Burin, Luciana Ambrósio, Sandro Ghisla, Suely Sampaio, Fabíola Castro
Publikováno v:
Revista Brasileira de Hematologia e Hemoterapia, Vol 38, Iss 2, Pp 128-134 (2016)
ABSTRACT BACKGROUND: Myeloproliferative neoplasms are Philadelphia chromosome-negative diseases characterized by hyperproliferation of mature myeloid cells, associated or not with the Janus kinase 2 tyrosine kinase mutation, JAK2V617F. As there is no
Externí odkaz:
https://doaj.org/article/445b3d9503574caf9fd7d66127a27d07
Autor:
Julian Koschmieder, Mirjam Fehling-Kaschek, Patrick Schaub, Sandro Ghisla, Anton Brausemann, Jens Timmer, Peter Beyer
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187628 (2017)
Phytoene desaturase (PDS) is an essential plant carotenoid biosynthetic enzyme and a prominent target of certain inhibitors, such as norflurazon, acting as bleaching herbicides. PDS catalyzes the introduction of two double bonds into 15-cis-phytoene,
Externí odkaz:
https://doaj.org/article/fab7c6b6c59e40b29afa1ab954c711d6
Autor:
Sandra Gemmecker, Patrick Schaub, Julian Koschmieder, Anton Brausemann, Friedel Drepper, Marta Rodriguez-Franco, Sandro Ghisla, Bettina Warscheid, Oliver Einsle, Peter Beyer
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131717 (2015)
Recombinant phytoene desaturase (PDS-His6) from rice was purified to near-homogeneity and shown to be enzymatically active in a biphasic, liposome-based assay system. The protein contains FAD as the sole protein-bound redox-cofactor. Benzoquinones, n
Externí odkaz:
https://doaj.org/article/9bd68630961b416e8aeb0a57ddca2f2e
Autor:
Patrick Schaub, Qiuju Yu, Sandra Gemmecker, Pierre Poussin-Courmontagne, Justine Mailliot, Alastair G McEwen, Sandro Ghisla, Salim Al-Babili, Jean Cavarelli, Peter Beyer
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39550 (2012)
CRTI-type phytoene desaturases prevailing in bacteria and fungi can form lycopene directly from phytoene while plants employ two distinct desaturases and two cis-tans isomerases for the same purpose. This property renders CRTI a valuable gene to engi
Externí odkaz:
https://doaj.org/article/649ad3c42fed4114a8ba280d7af8b0af
Autor:
Sandra Mara Burin, Maria Gabriela Berzoti Coelho, Alexandre Ferro Aissa, Ana Paula Zambuzi Cardoso Marsola, Fabíola Attié de Castro, Amanda Tomie Ouchida, Tássia Rafaella Costa, Suely Vilela Sampaio, Belinda Pinto-Simões, Sandro Ghisla, Lusânia Maria Greggi Antunes, Carlos Curti
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of the Bcr-Abl tyrosine kinase protein, which confers resistance to apoptosis in leukemic cells. Tyrosine kinase inhibitors (TKIs) are effectively used to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ebf1ba3459cbed45885f5ca8a6d777
https://doi.org/10.1016/j.ijbiomac.2016.01.069
https://doi.org/10.1016/j.ijbiomac.2016.01.069
Autor:
Jerry Vockley, Wolfgang Buckel, Johannes Zschocke, Georg F. Hoffmann, Sandro Ghisla, Michael Liesert, Marina Morath, Matthias Mack, Verena Peters
Publikováno v:
JIMD Reports, Vol 47, Iss 1, Pp 30-34 (2019)
JIMD Reports
JIMD Reports
3‐Hydroxyglutaric acid (3‐OH‐GA) in urine has been identified as the most reliable diagnostic marker for glutaric aciduria type I (GA I). We showed that hydratation of glutaconyl‐CoA to 3‐hydroxyglutaryl‐CoA, which is subsequently hydroly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed22b5f03349ed178715c119a1b2638
https://pubmed.ncbi.nlm.nih.gov/31240164
https://pubmed.ncbi.nlm.nih.gov/31240164
Autor:
Peter Beyer, Sandro Ghisla, Florian Wüst, Patrick Schaub, Martina Vermathen, Salim Al-Babili, Mark Bruno, Adrian Alder, Rob van der Steen
Publikováno v:
FEBS letters. 591(5)
Strigolactones are a new class of phytohormones synthesized from carotenoids via carlactone. The complex structure of carlactone is not easily deducible from its precursor, a cis-configured β-carotene cleavage product, and is thus formed via a poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c290d8ca5b222255f5be23567e79bf
https://pubmed.ncbi.nlm.nih.gov/28186640
https://pubmed.ncbi.nlm.nih.gov/28186640
Publikováno v:
Journal of Biological Chemistry. 286:40987-40998
d-Amino acid oxidase (DAAO) from pig has been reported to catalyze the β-elimination of Cl− from βCl-d-alanine via abstraction of the substrate α-H as H+ (“carbanion mechanism”) (Walsh, C. T., Schonbrunn, A., and Abeles, R. H. (1971) J. Biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317651e4aeb66131b6fe890db5de5224
https://doi.org/10.1074/jbc.m111.266536
https://doi.org/10.1074/jbc.m111.266536
Publikováno v:
Journal of Biological Chemistry. 286:8666-8676
The carotene cis-trans isomerase CRTISO is a constituent of the carotene desaturation pathway as evolved in cyanobacteria and prevailing in plants, in which a tetra-cis-lycopene species, termed prolycopene, is formed. CRTISO, an evolutionary descenda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54948bf44614393d70f10e08bbba0c70
https://doi.org/10.1074/jbc.m110.208017
https://doi.org/10.1074/jbc.m110.208017