Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sandro Da Mesquita"'
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-21 (2023)
Abstract Alzheimer’s disease (AD) is an aging-related form of dementia associated with the accumulation of pathological aggregates of amyloid beta and neurofibrillary tangles in the brain. These phenomena are accompanied by exacerbated inflammation
Externí odkaz:
https://doaj.org/article/2fd98d8c23294bea8b68f8f550b4df47
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/fb2824d3db1f4fa8ba62933220d7e4c5
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
A genuine and functional lymphatic vascular system is found in the meninges that sheath the central nervous system (CNS). This unexpected (re)discovery led to a reevaluation of CNS fluid and solute drainage mechanisms, neuroimmune interactions and th
Externí odkaz:
https://doaj.org/article/7bf7598fdb624fc08f4accf99b100072
Autor:
Sandro Da Mesquita, Ana Catarina Ferreira, Joao C Sousa, Nadine Correia Santos, Margarida eCorreia-Neves, Nuno eSousa, Joana A Palha, Fernanda eMarques
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 6 (2012)
Iron is essential for mammalian cellular homeostasis. However, in excess, it promotes free radical formation and is associated with aging-related progressive deterioration and with neurodegenerative disorders such as Alzheimer’s disease (AD). There
Externí odkaz:
https://doaj.org/article/7231d92d104145eb842674dd65d3f667
Autor:
Dylan H. Goldman, Taitea Dykstra, Igor Smirnov, Susan M. Blackburn, Sandro Da Mesquita, Jonathan Kipnis, Jasmin Herz
Publikováno v:
Nature Aging. 2:704-713
Autor:
Sandro Da Mesquita
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Jonathan Kipnis, Sandro Da Mesquita, Martin R. Farlow, Morgan Wall, David M. Holtzman, Emily Farber, Stephen S. Rich, Zachary Papadopoulos, Carlos Cruchaga, Andrea Francesca Salvador, Mary Grace Milam, Jasmeer P. Chhatwal, Bruno A. Benitez, Dylan H. Goldman, Fabiana H.G. Farias, Kalil Alves de Lima, Richard J. Perrin, Hong Jiang, Logan Brase, Chinnappa D. Kodira, Antoine Louveau, Suna Onengut-Gumuscu, Jasmin Herz, Igor Smirnov, Wendy Baker, Nisha Dabhi, Tatiana Kennedy, Celeste M. Karch, Oscar Harari, Taitea Dykstra
Publikováno v:
Nature
Alzheimer’s disease (AD) is the most prevalent cause of dementia1. Although there is no effective treatment for AD, passive immunotherapy with monoclonal antibodies against amyloid beta (Aβ) is a promising therapeutic strategy2,3. Meningeal lympha
Publikováno v:
Funk, K E, Montagne, A, Falcao, A M & Da Mesquita, S 2022, ' Editorial : Multifaceted Interactions Between Immunity and the Diseased Brain ', Frontiers in Cellular Neuroscience, vol. 16, 941590 . https://doi.org/10.3389/fncel.2022.941590
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ef18a3bf9d265e200698433adbea0e
https://www.pure.ed.ac.uk/ws/files/294756684/fncel_16_941590.pdf
https://www.pure.ed.ac.uk/ws/files/294756684/fncel_16_941590.pdf
Autor:
Aymeric Silvin, Stefan Uderhardt, Cecile Piot, Sandro Da Mesquita, Katharine Yang, Laufey Geirsdottir, Kevin Mulder, David Eyal, Zhaoyuan Liu, Cecile Bridlance, Morgane Sonia Thion, Xiao Meng Zhang, Wan Ting Kong, Marc Deloger, Vasco Fontes, Assaf Weiner, Rachel Ee, Regine Dress, Jing Wen Hang, Akhila Balachander, Svetoslav Chakarov, Benoit Malleret, Garett Dunsmore, Olivier Cexus, Jinmiao Chen, Sonia Garel, Charles Antoine Dutertre, Ido Amit, Jonathan Kipnis, Florent Ginhoux
Publikováno v:
Immunity
Immunity, 2022, 55 (8), pp.1448-1465.e6. ⟨10.1016/j.immuni.2022.07.004⟩
Immunity, 2022, 55 (8), pp.1448-1465.e6. ⟨10.1016/j.immuni.2022.07.004⟩
Brain macrophage populations include parenchymal microglia, border-associated macrophages, and recruited monocyte-derived cells; together, they control brain development and homeostasis but are also implicated in aging pathogenesis and neurodegenerat
Autor:
Maria Beatriz Lopes, William Sam Cao, Jonathan Kipnis, Igor Smirnov, Justin Rustenhoven, Wendy Baker, Xinmin Xie, Zach Papadopoulos, Kalil Alves de Lima, Sandro Da Mesquita, Tornike Mamuladze, Jasmin Herz, Andrea Francesca Salvador, Morgan Wall, Guilherme Cesar Martelossi Cebinelli
Publikováno v:
Nature Immunology. 21:1421-1429
Interleukin (IL)-17a has been highly conserved during evolution of the vertebrate immune system and widely studied in contexts of infection and autoimmunity. Studies suggest that IL-17a promotes behavioral changes in experimental models of autism and