Zobrazeno 1 - 10
of 385
pro vyhledávání: '"Sandro Sonnino"'
Autor:
Giulia Lunghi, Erika Di Biase, Emma Veronica Carsana, Alexandre Henriques, Noelle Callizot, Laura Mauri, Maria Grazia Ciampa, Luigi Mari, Nicoletta Loberto, Massimo Aureli, Sandro Sonnino, Michael Spedding, Elena Chiricozzi, Maria Fazzari
Publikováno v:
FEBS Open Bio, Vol 13, Iss 12, Pp 2324-2341 (2023)
Alterations in glycosphingolipid metabolism have been linked to the pathophysiological mechanisms of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting motor neurons. Accordingly, administration of GM1, a sialic acid‐contain
Externí odkaz:
https://doaj.org/article/bc90ee2630b94cd7baec16a20f019b9f
Autor:
Ioannis Tsagakis, Sandro Sonnino
Publikováno v:
FEBS Open Bio, Vol 13, Iss 9, Pp 1544-1547 (2023)
Sandro Sonnino is one of the founding members of the Editorial Board of FEBS Open Bio, having joined in 2011. He is also a member of the Editorial Board of FEBS Letters and is the Editor‐in‐Chief of Glycoconjugate Journal. He is full professor of
Externí odkaz:
https://doaj.org/article/980822512ddd4016bc59d0a48ec009c5
Autor:
Sandro Sonnino
Publikováno v:
FEBS Open Bio, Vol 13, Iss 9, Pp 1548-1557 (2023)
GM1 is one of the main gangliosides of the nervous system, and it exerts neurotrophic and neuroprotective properties in neurons. It is involved in many processes necessary for the correct physiology of neuronal cells. In particular, it is necessary f
Externí odkaz:
https://doaj.org/article/e370628fb97e4ddaaa98339dc8b32e5e
Publikováno v:
FEBS Open Bio, Vol 11, Iss 12, Pp 3193-3200 (2021)
Gangliosides are particularly abundant in the central nervous system, where they are mainly associated with the synaptic membranes. Their structure underlies a specific role in determining several cell physiological processes of the nervous system. T
Externí odkaz:
https://doaj.org/article/eb22c8b319e8439896d7dc9d57e2ea93
Autor:
Maria Fazzari, Giulia Lunghi, Alexandre Henriques, Noëlle Callizot, Maria Grazia Ciampa, Laura Mauri, Simona Prioni, Emma Veronica Carsana, Nicoletta Loberto, Massimo Aureli, Luigi Mari, Sandro Sonnino, Elena Chiricozzi, Erika Di Biase
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1305 (2023)
Past evidence has shown that the exogenous administration of GM1 ganglioside slowed neuronal death in preclinical models of Parkinson’s disease, a neurodegenerative disorder characterized by the progressive loss of dopamine-producing neurons: howev
Externí odkaz:
https://doaj.org/article/8a1943fc716f42f4923a8d9f878d1326
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 5, Pp 636-654 (2020)
Lipid rafts are small, dynamic membrane areas characterized by the clustering of selected membrane lipids as the result of the spontaneous separation of glycolipids, sphingolipids, and cholesterol in a liquid-ordered phase. The exact dynamics underly
Externí odkaz:
https://doaj.org/article/aa7f90d833fd4f7fa3e3a9e29dd8a822
Autor:
Laura Mauri, Sandro Sonnino
Publikováno v:
Glycoconjugate Journal. 40:269-276
The structure and properties of a group of gangliosides modified by mild alkaline treatment are discussed. We will present the occurrence and the structure of gangliosides carrying the N-acetyneuraminic acid O-acetylated in position 9, the Neu5,9Ac2,
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 363 (2022)
Gangliosides are glycosphingolipids which are particularly abundant in the plasma membrane of mammalian neurons. The knowledge of their presence in the human brain dates back to the end of 19th century, but their structure was determined much later,
Externí odkaz:
https://doaj.org/article/214647c3fe6a49b388335d7598109068
Autor:
Giulia Lunghi, Maria Fazzari, Maria Grazia Ciampa, Laura Mauri, Erika Di Biase, Elena Chiricozzi, Sandro Sonnino
Publikováno v:
FEBS Letters. 596:3124-3132
The interactions between gangliosides and proteins belonging to the same or different lipid domains and their influence on physiological and pathological states have been analysed in detail. A well-known factor impacting on lipid-protein interactions
Autor:
Sara Grassi, Laura Mauri, Simona Prioni, Livia Cabitta, Sandro Sonnino, Alessandro Prinetti, Paola Giussani
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The central nervous system is characterized by a high content of sphingolipids and by a high diversity in terms of different structures. Stage- and cell-specific sphingolipid metabolism and expression are crucial for brain development and maintenance
Externí odkaz:
https://doaj.org/article/c03dd96f4b1e414e8fba62d07061443b