Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sandro, Norelli"'
Publikováno v:
Pathogens, Vol 4, Iss 4, Pp 697-707 (2015)
The widespread occurrence of vaginal candidiasis and the development of resistance against anti-fungal agents has stimulated interest in understanding the pathogenesis of this disease. The aim of our work was to characterize, in an animal model of va
Externí odkaz:
https://doaj.org/article/86e0e85c60964e299a9ab270584012e9
Autor:
Iart Luca Shytaj, Sandro Norelli, Barbara Chirullo, Alessandro Della Corte, Matt Collins, Jake Yalley-Ogunro, Jack Greenhouse, Nunzio Iraci, Edward P Acosta, Maria Letizia Barreca, Mark G Lewis, Andrea Savarino
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002774 (2012)
Stably suppressed viremia during ART is essential for establishing reliable simian models for HIV/AIDS. We tested the efficacy of a multidrug ART (highly intensified ART) in a wide range of viremic conditions (10³-10⁷) viral RNA copies/mL) in SIVm
Externí odkaz:
https://doaj.org/article/0be750d7a056476b967074d1f16fbf0f
Autor:
Ravirajsinh N. Jadeja, Simone Beninati, Antonio Facchiano, Roberto Nisini, Manuela Bartoli, Francesco Facchiano, Stefano Pieretti, Cinzia Forni, Claudio Tabolacci, Giorgia Valle, Daniela D'Arcangelo, Sandro Norelli
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2019 (2019)
BioMed Research International, Vol 2019 (2019)
Aging is related to a number of functional and morphological changes leading to progressive decline of the biological functions of an organism. Reactive Oxygen Species (ROS), released by several endogenous and exogenous processes, may cause important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f352bc94c8150d894ae7f00edf3e0e7
http://hdl.handle.net/2108/227777
http://hdl.handle.net/2108/227777
Publikováno v:
Pathogens
Pathogens, Vol 4, Iss 4, Pp 697-707 (2015)
Pathogens, Vol 4, Iss 4, Pp 697-707 (2015)
The widespread occurrence of vaginal candidiasis and the development of resistance against anti-fungal agents has stimulated interest in understanding the pathogenesis of this disease. The aim of our work was to characterize, in an animal model of va
Autor:
Sandro Norelli
Publikováno v:
Medical Hypotheses. 83:659-663
This paper discusses potential avenues to abate the last bulwark to the HIV-1 eradication i.e. viral reservoirs in the body, consisting mainly of viral DNA hidden, in latent form, into long-lived memory CD4+ T-cells, resulting unaffected by either dr
Autor:
Lewis, Mark G., Sandrina, Dafonseca, Chamont, N., Nicolas, Chomont, Palamara, ANNA TERESA, Tardugno, Maria, Mai, Antonello, Matt, Collins, Wagner, Wendeline L., Jake Yalley Ogunro, Jack, Greenhouse, Barbara, Chirullo, Sandro, Norelli, Enrico, Garaci, Andrea, Savarino
Publikováno v:
AIDS. 25:1347-1356
Objectives: A small pool of long-lived memory CD4 + T cells harboring the retroviral genome is one main obstacle to HIV eradication. We tested the impact of the gold compound, auranofin, on phenotype and viability of CD4 + T cells in vitro, and on pe
Autor:
Alessandra Ciervo, Mauro Pistello, Massimo Ciccozzi, Mauro Bendinelli, Sary El Daker, Sandro Norelli, Daniela D'Ostilio, Fabiana Taglia, Roberto Cauda, Fabiola Mancini, Andrea Savarino, Maria Letizia Barreca, Federico Mele, Anna Ruggieri
Publikováno v:
Current HIV Research. 6:306-317
The feline AIDS model for HIV-1 treatment failed in the 1990s, due to structural features resembling protease inhibitor (PI) resistant HIV-1 variants. Widespread drug-resistance to PIs now invokes the possibility of rescuing feline immunodeficiency v
Publikováno v:
Expert Opinion on Therapeutic Patents
Coronavirus replication offers several attractive targets for chemotherapy. These include: viral entry (inhibited by chloroquine and peptides); viral RNA (targeted by antisense approaches/RNAi); the main protease 3CLpro (inhibited by peptidic molecul
Autor:
Sandro Norelli, Jack Greenhouse, Jake Yalley-Ogunro, Andrea Savarino, Barbara Chirullo, Maria Letizia Barreca, Iart Luca Shytaj, Edward P. Acosta, Nunzio Iraci, Mark G. Lewis, Matt Collins, Alessandro Della Corte
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 8, Iss 6, p e1002774 (2012)
PLoS Pathogens, Vol 8, Iss 6, p e1002774 (2012)
Stably suppressed viremia during ART is essential for establishing reliable simian models for HIV/AIDS. We tested the efficacy of a multidrug ART (highly intensified ART) in a wide range of viremic conditions (103–107 viral RNA copies/mL) in SIVmac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c553a03dcbe43fe8c7185ebe1c6aaf2f
http://hdl.handle.net/11570/3189029
http://hdl.handle.net/11570/3189029
Autor:
Jack Greenhouse, Mark G. Lewis, Barbara Chirullo, Andrea Savarino, Maria Letizia Barreca, Jake Yalley-Ogunro, Nunzio Iraci, Fausto Titti, Matt Collins, Sandro Norelli, Enrico Garaci
Publikováno v:
Retrovirology, Vol 7, Iss 1, p 21 (2010)
Retrovirology
Retrovirology
BackgroundIn this study we successfully created a new approach to ART in SIVmac251 infected nonhuman primates. This drug regimen is entirely based on drugs affecting the pre-integration stages of replication and consists of only two nucleotidic/nucle