Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Sandrine Vessillier"'
Autor:
Carl G. Simon, Erich H. Bozenhardt, Christina M. Celluzzi, David Dobnik, Melanie L. Grant, Uma Lakshmipathy, Thiana Nebel, Linda Peltier, Anthony Ratcliffe, James L. Sherley, Glyn N. Stacey, Rouzbeh R. Taghizadeh, Eddie H. P. Tan, Sandrine Vessillier
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract One of the most challenging aspects of developing advanced cell therapy products (CTPs) is defining the mechanism of action (MOA), potency and efficacy of the product. This perspective examines these concepts and presents helpful ways to thi
Externí odkaz:
https://doaj.org/article/1a4c1b7ac9dd4b808e25bb9e5b77ce01
Autor:
Neil Berry, Deborah Ferguson, Sarah Kempster, Jo Hall, Claire Ham, Adrian Jenkins, Vicky Rannow, Elaine Giles, Rose Leahy, Sara Goulding, Arturo Fernandez, Yemisi Adedeji, Sandrine Vessillier, Deepa Rajagopal, Sandra Prior, Yann Le Duff, Matthew Hurley, Sarah Gilbert, Martin Fritzsche, Ryan Mate, Nicola Rose, Robert J. Francis, Kirsty MacLellan-Gibson, Alejandro Suarez-Bonnet, Simon Priestnall, Neil Almond
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract SARS-CoV-2 exhibits a diverse host species range with variable outcomes, enabling differential host susceptibility studies to assess suitability for pre-clinical countermeasure and pathogenesis studies. Baseline virological, molecular and pa
Externí odkaz:
https://doaj.org/article/0bdbc34a3c9f4aa9acf1c9f0c03b6ceb
Autor:
Nilofar Faruqui, Andreas Kummrow, Boqiang Fu, Carla Divieto, Fabiola Rojas, Florence Kisulu, Janaina J. V. Cavalcante, Jing Wang, Jonathan Campbell, Juliana L. Martins, Jun-Hyuk Choi, Maria Paola Sassi, Massimo Zucco, Maxim Vonsky, Sandrine Vessillier, Shan Zou, Shin-Ichiro Fujii, Maxim G. Ryadnov
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2020)
The symptomatic irreproducibility of data in biomedicine and biotechnology prompts the need for higher order measurements of cells in their native and near-native environments. Such measurements may support the adoption of new technologies as well as
Externí odkaz:
https://doaj.org/article/c9f92284cc31451f9be8eac8fca987bb
Publikováno v:
Viruses, Vol 13, Iss 8, p 1528 (2021)
Lentiviral vectors have played a critical role in the emergence of gene-modified cell therapies, specifically T cell therapies. Tisagenlecleucel (Kymriah), axicabtagene ciloleucel (Yescarta) and most recently brexucabtagene autoleucel (Tecartus) are
Externí odkaz:
https://doaj.org/article/2d62769bd9554d35a58221ab3996c089
Autor:
Y K Stella Man, Danielle DiCara, Nicole Chan, Sandrine Vessillier, Stephen J Mather, Michelle L Rowe, Mark J Howard, John F Marshall, Ahuva Nissim
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70452 (2013)
We have developed a structurally-guided scaffold phage display strategy for identification of ligand mimetic bio-therapeutics. As a proof of concept we used the ligand of integrin αvβ6, a tumour cell surface receptor and a major new target for imag
Externí odkaz:
https://doaj.org/article/c5c4328f840b4570af524208fe1ac30b
Autor:
Jiwon Yang, Jing Jiao, Kyle M. Draheim, Guoxiang Yang, Hongyuan Yang, Li‐Chin Yao, Leonard D. Shultz, Dale L. Greiner, Deepa Rajagopal, Sandrine Vessillier, Curtis C. Maier, Sunish Mohanan, Danying Cai, Mingshan Cheng, Michael A. Brehm, James G. Keck
Publikováno v:
The FASEB Journal. 37
Autor:
Jonathan Campbell, Jana Höckner, Sandrine Vessillier, Luisa Saraiva, Andreas Kummrow, Yu-Zhong Zhang, Yingying Liu, Ji Youn Lee, Andrea Engel, Peter Rigsby, Carla Divieto, Lili Wang, Andreas Ruf, Burhanettin Yalcinkaya, Eleanor Atkinson, Tamara Lekishvili, Muslum Akgoz, Richard Stebbings, Orla O'Shea, Jörg Neukammer, Martin Kammel, Jing Wang, Maria Paola Sassi, Adolfas K. Gaigalas
Publikováno v:
Cytometry. Part B, Clinical Cytometry
Background Over 2,000 people a year in the United Kingdom need a bone marrow or blood stem cell transplant. It is important to accurately quantify the hematopoietic stem cells to predict whether the transplant will be successful in replenishing the i
Autor:
Jack Price, Christian K. Schneider, Anika Jones, James E. Eyles, Glyn N. Stacey, Sandrine Vessillier
Publikováno v:
Journal of Chemical Technology & Biotechnology
Recent accelerated approvals of Chimeric Antigen Receptor T‐cell (CAR‐T) therapies targeting refractory haematological malignancies underscore the potential for this novel technology platform to provide new therapeutic options for oncology areas
Autor:
Joseph R Piccotti, Richard Stebbings, Lynn M. O’Donnell, Madeline M. Fort, Babette Wolf, Aarron T. Willingham, Heather Hinton, Divya Mekala, Sandrine Vessillier, Kimberly L. Nadwodny, Karin Staflin, Peter Rigsby
Publikováno v:
Cytokine: X, Vol 2, Iss 4, Pp 100042-(2020)
Cytokine X
Cytokine X
Immunomodulatory therapeutics such as monoclonal antibodies (mAb) carry an inherent risk of undesired immune reactions. One such risk is cytokine release syndrome (CRS), a rapid systemic inflammatory response characterized by the secretion of pro-inf
Autor:
Sandrine Vessillier, David A. Lee, R. K. Tilwani, Belinda Pingguan-Murphy, Dan L. Bader, Tina T. Chowdhury
Publikováno v:
Inflammation Research
Objective and design: Oxygen tension and biomechanical signals are factors that regulate inflammatory mechanisms in chondrocytes. We examined whether low oxygen tension influenced the cells response to TNF? and dynamic compression.Materials and metho