Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sandrine Spriggs"'
Autor:
Ramya Rajagopal, Maria T. Baltazar, Paul L. Carmichael, Matthew P. Dent, Julia Head, Hequn Li, Iris Muller, Joe Reynolds, Kritika Sadh, Wendy Simpson, Sandrine Spriggs, Andrew White, Predrag Kukic
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
New Approach Methodologies (NAMs) promise to offer a unique opportunity to enable human-relevant safety decisions to be made without the need for animal testing in the context of exposure-driven Next Generation Risk Assessment (NGRA). Protecting huma
Externí odkaz:
https://doaj.org/article/c78d1eb51cd241b595cd1265d5eaa514
Publikováno v:
Toxicology letters. 292
Understanding skin metabolism is key to improve in vitro to in vivo extrapolations used to inform risk assessments of topically applied products. However, published literature is scarce and usually covers a limited and non-representative number of do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53784e058e0695cdac1045bb25f323f2
https://pubmed.ncbi.nlm.nih.gov/29709425
https://pubmed.ncbi.nlm.nih.gov/29709425
Autor:
Neil R. Kitteringham, Maja Aleksic, Dean J. Naisbitt, Sandrine Spriggs, David Sheffield, Adedamola Olayanju
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 154(1)
Glutathione (GSH) plays a major role in skin detoxification processes due to its ability to conjugate electrophilic exogenous compounds with, and sometimes without, catalysis by glutathione-s-transferase (GST). GST activity has been demonstrated both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0ba6c13d831e1651cea5a019f0a3c7
https://pubmed.ncbi.nlm.nih.gov/27492222
https://pubmed.ncbi.nlm.nih.gov/27492222