Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Sandrine Sagan"'
Autor:
Sébastien Cardon, Yadira P. Hervis, Gérard Bolbach, Chrystel Lopin-Bon, Jean-Claude Jacquinet, Françoise Illien, Astrid Walrant, Delphine Ravault, Bingwei He, Laura Molina, Fabienne Burlina, Olivier Lequin, Alain Joliot, Ludovic Carlier, Sandrine Sagan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Engrailed2 (En2) is a transcription factor that transfers from cell to cell through unconventional pathways. The poorly understood internalization mechanism of this cationic protein is proposed to require an initial interaction with cell-sur
Externí odkaz:
https://doaj.org/article/c684e2cdb0ba43a69d9c0fdf51449845
Autor:
Mo’ath Yousef, Ildikó Szabó, József Murányi, Françoise Illien, Dóra Soltész, Csaba Bató, Gabriella Tóth, Gyula Batta, Péter Nagy, Sandrine Sagan, Zoltán Bánóczi
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 141 (2022)
Cell-penetrating peptides represent an emerging class of carriers capable of effective cellular delivery. This work demonstrates the preparation and investigation of efficient CPPs. We have already shown that the presence of 4-((4-(dimethylamino)phen
Externí odkaz:
https://doaj.org/article/4d7fc7b8b4d047cfb3506feb7a9f7d34
Publikováno v:
Crystals, Vol 11, Iss 9, p 1032 (2021)
Tryptophan is an aromatic amino acid with unique physico-chemical properties. It is often encountered in membrane proteins, especially at the level of the water/bilayer interface. It plays a role in membrane protein stabilization, anchoring and orien
Externí odkaz:
https://doaj.org/article/3226e5a8ebd74f24ac9f14cf07471b42
Publikováno v:
EuPA Open Proteomics, Vol 10, Iss C, Pp 1-8 (2016)
EWS-FLI1 expression in NIH-3T3 fibroblasts has a profound impact on the phenotype, resulting in the cytoskeleton and adhesive capacity disorganization (EF cells). Besides this, (R/W)9, a cell-penetrating peptide (CPP), has an intrinsic actin remodeli
Externí odkaz:
https://doaj.org/article/d0a488ee0faf43619d55ac68f90fffdf
Autor:
Michaël Trichet, Rosamaria Lappano, Mathilde Belnou, Lilian Shadai Salazar Vazquez, Isabel Alves, Delphine Ravault, Sandrine Sagan, Lucie Khemtemourian, Marcello Maggiolini, Yves Jacquot
Publikováno v:
Cells, Vol 9, Iss 2, p 447 (2020)
The peptide ERα17p, which corresponds to the 295-311 fragment of the hinge/AF2 domains of the human estrogen receptor α (ERα), exerts apoptosis in breast cancer cells through a mechanism involving the G protein-coupled estrogen-dependent receptor
Externí odkaz:
https://doaj.org/article/a6fc457b658e4d909016ddfd53836faf
Autor:
Sébastien Cardon, Emmanuelle Sachon, Ludovic Carlier, Thierry Drujon, Astrid Walrant, Estefanía Alemán-Navarro, Verónica Martínez-Osorio, Dominique Guianvarc'h, Sandrine Sagan, Yannick Fleury, Rodrigue Marquant, Christophe Piesse, Yvonne Rosenstein, Constance Auvynet, Claire Lacombe
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205727 (2018)
The occurrence of nosocomial infections has been on the rise for the past twenty years. Notably, infections caused by the Gram-positive bacteria Staphylococcus aureus represent a major clinical problem, as an increase in antibiotic multi-resistant st
Externí odkaz:
https://doaj.org/article/78b544e90a0947459e588490d3adcb67
Publikováno v:
EuPA Open Proteomics, Vol 3, Iss C, Pp 229-238 (2014)
Cell penetrating peptides (CPPs) are attracting attention because of their ability to deliver biologically active molecules into cells. On their way they can interact with membrane and intracellular proteins. To fully understand and improve CPP effic
Externí odkaz:
https://doaj.org/article/af7f0b5223ff4360b5c68414a3b63b3a
Autor:
Héloise Boullet, Fayçal Bentot, Arnaud Hequet, Carine Ganem-Elbaz, Chérine Bechara, Emeline Pacreau, Pierre Launay, Sandrine Sagan, Claude Jolivalt, Claire Lacombe, Roba Moumné, Philippe Karoyan
Publikováno v:
Molecules, Vol 24, Iss 9, p 1702 (2019)
Antimicrobial peptides (AMPs) are considered as potential therapeutic sources of future antibiotics because of their broad-spectrum activities and alternative mechanisms of action compared to conventional antibiotics. Although AMPs present considerab
Externí odkaz:
https://doaj.org/article/49975b721d3547de8eb5adf9b7983f7a
Autor:
Isabel D Alves, Cherine Bechara, Astrid Walrant, Yefim Zaltsman, Chen-Yu Jiao, Sandrine Sagan
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24096 (2011)
BackgroundPenetratin is a positively charged cell-penetrating peptide (CPP) that has the ability to bind negatively charged membrane components, such as glycosaminoglycans and anionic lipids. Whether this primary interaction of penetratin with these
Externí odkaz:
https://doaj.org/article/ceda8bd94deb4ed59e0c63847645f2a7
Publikováno v:
PLoS Pathogens, Vol 6, p e1000975 (2010)
CD4(+) T cell loss is central to HIV pathogenesis. In the initial weeks post-infection, the great majority of dying cells are uninfected CD4(+) T cells. We previously showed that the 3S motif of HIV-1 gp41 induces surface expression of NKp44L, a cell
Externí odkaz:
https://doaj.org/article/b4402a58e74a4efb96a12b760414498e