Donor platelets stored for at least 3 days can elicit activation marker expression by the recipient's blood mononuclear cells: an in vitrostudy

Autor: Patricia Chavarin, Olivier Garraud, Rémi Courbil, Fabrice Cognasse, Hind Hamzeh-Cognasse, P. Fabrigli, Sophie Acquart, Sandrine Lafarge

Publikováno v: Transfusion. 49:91-98

BACKGROUND: Recent studies have demonstrated that infused platelets (PLTs) can promote inflammation. The objective of this study was to evaluate the impact of storage of transfusion-grade PLTs on the peripheral blood mononuclear cells (PBMNCs) of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811652bf9e6f55d304f420023ea4ad67
https://doi.org/10.1111/j.1537-2995.2008.01931.x

ZAP70 expression directly promotes chronic lymphocytic leukaemia cell adhesion to bone marrow stromal cells

Autor: Spencer B. Gibson, Samantha D. Pauls, James B. Johnston, Aaron J. Marshall, Hongzhao Li, Sandrine Lafarge, Sen Hou

Publikováno v: British journal of haematology. 168(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140c72c5120984437223edc970d31914
https://pubmed.ncbi.nlm.nih.gov/25088442

Frequent Occurrence of Highly Expanded but Unrelated B-Cell Clones in Patients with Multiple Myeloma

Autor: Jitra Kriangkum, James B. Johnston, Carina Debes Marun, Andrew R. Belch, Spencer B. Gibson, Sandrine Lafarge, Sarah N. Motz, Linda M. Pilarski, Christopher P. Venner

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 5, p e64927 (2013)

Clonal diversity in multiple myeloma (MM) includes both MM-related and MM-unrelated clonal expansions which are subject to dominance exerted by the MM clone. Here we show evidence for the existence of minor but highly expanded unrelated B-cell clones

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5c0e11aeadbaf121424f94c372afa3
http://europepmc.org/articles/PMC3665682

Complexes between nuclear factor-κB p65 and signal transducer and activator of transcription 3 are key actors in inducing activation-induced cytidine deaminase expression and immunoglobulin A production in CD40L plus interleukin-10-treated human blood B cells

Autor: Olivier Garraud, Sandrine Lafarge, Yolande Richard, Michel Cogné, Bruno Pozzetto, Fabrice Cognasse, Hind Hamzeh-Cognasse

Publikováno v: Clinical and Experimental Immunology
Clinical and Experimental Immunology, Wiley, 2011, 166 (2), pp.171-83. ⟨10.1111/j.1365-2249.2011.04465.x⟩

Summary The signal transducer and activator of transcription 3 (STAT3) transcription factor pathway plays an important role in many biological phenomena. STAT3 transcription is triggered by cytokine-associated signals. Here, we use isolated human B c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c60023f39e4cb2c266ee37d45f44634
https://hal.archives-ouvertes.fr/hal-00697663

Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human platelets

Autor: Sandrine Lafarge, Olivier Garraud, A. Mcnicol, Bruno Pozzetto, Hind Hamzeh-Cognasse, Fabrice Cognasse, Olivier Delézay

Publikováno v: British journal of haematology. 141(1)

Blood platelets link the processes of haemostasis and inflammation. This study examined the immunomodulatory factors released by platelets after Toll-Like Receptor 4 (TLR4) engagement on their surfaces. Monoclonal anti-human FcgammaRII Ab (IV.3)-trea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9742aaecd048ed22eda3e21bb061e32d
https://pubmed.ncbi.nlm.nih.gov/18279456