Zobrazeno 1 - 10
of 435
pro vyhledávání: '"Sandrine Florquin"'
Autor:
Anita E. Grootemaat, Niek Wiersma, Sanne van der Niet, Irene M. Schimmel, Sandrine Florquin, Eric A. Reits, Sara E. Miller, Nicole N. van der Wel
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT In this study, we investigated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins and virus particles can be detected (i) in post-mortem kidney of fatal coronavirus disease 2019 (COVID-19) patients and (ii) i
Externí odkaz:
https://doaj.org/article/9d7d820279094e5d828e7e4800f35143
Autor:
Ye Liu, Lotte Kors, Loes M. Butter, Geurt Stokman, Nike Claessen, Coert J. Zuurbier, Stephen E. Girardin, Jaklien C. Leemans, Sandrine Florquin, Alessandra Tammaro
Publikováno v:
Cells, Vol 13, Iss 1, p 23 (2023)
Background: Chronic kidney disease often leads to kidney dysfunction due to renal fibrosis, regardless of the initial cause of kidney damage. Macrophages are crucial players in the progression of renal fibrosis as they stimulate inflammation, activat
Externí odkaz:
https://doaj.org/article/a19ace71ab7e4aec9b0f3be9ba50d498
Autor:
Zhe Liu, Alexander P.N.A. De Porto, Regina De Beer, Joris J.T.H. Roelofs, Onno J. De Boer, Sandrine Florquin, Cornelis Van’t Veer, Rudi W. Hendriks, Tom Van der Poll, Alex F. De Vos
Publikováno v:
Journal of Innate Immunity, Pp 1-15 (2022)
Humans with dysfunctional Bruton’s tyrosine kinase (Btk) are highly susceptible to bacterial infections. Compelling evidence indicates that Btk is essential for B cell-mediated immunity, whereas its role in myeloid cell-mediated immunity against in
Externí odkaz:
https://doaj.org/article/9a182f02185d4c06a7e0960e061482bc
Publikováno v:
Platelets, Vol 31, Iss 3, Pp 383-391 (2020)
The pathophysiology of renal ischemia/reperfusion (I/R) injury is characterized by excessive activation of inflammation and coagulation processes followed by abnormal renal tissue repair, resulting in renal injury and function loss. Platelets are imp
Externí odkaz:
https://doaj.org/article/a2ba26a45e524700b9ae46908d01e484
Autor:
Desirée Perlee, Alex F. de Vos, Brendon P. Scicluna, Anja Maag, Pablo Mancheño, Olga de la Rosa, Wilfried Dalemans, Sandrine Florquin, Cornelis van’t Veer, Eleuterio Lombardo, Tom van der Poll
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-9 (2019)
Abstract Background Adult mesenchymal stem cells (MSCs) improve the host response during experimental sepsis in animals. MSCs from various sources express a procoagulant activity that has been linked to the expression of tissue factor. This study sou
Externí odkaz:
https://doaj.org/article/9ae00b646c894373ae7289ae8e6bde7c
Autor:
Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Joris J. T. H. Roelofs, Onno J. de Boer, Joke M. M. den Haan, Rudi W. Hendriks, Cornelis van ‘t Veer, Tom van der Poll, Alex F. de Vos
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Bruton’s tyrosine kinase (Btk) is a cytoplasmic kinase expressed in B cells and myeloid cells. It is essential for B cell development and natural antibody-mediated host defense against bacteria in humans and mice, but little is known about the role
Externí odkaz:
https://doaj.org/article/6534ee5b3c2444c6b14ce70febc59ba2
Autor:
Arjan J. Kwakernaak, Sophie J. Bernelot Moens, Marc L. Hilhorst, Sandrine Florquin, Niels W.C.J. van deDonk, Josephine M.I. Vos
Publikováno v:
eJHaem, Vol 3, Iss 2, Pp 565-566 (2022)
Externí odkaz:
https://doaj.org/article/6a23e8b3f59a4b6cbbab0542d71a77e1
Autor:
Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Onno J. de Boer, Rudi W. Hendriks, Tom van der Poll, Alex F. de Vos
Publikováno v:
Molecular Medicine, Vol 25, Iss 1, Pp 1-10 (2019)
Abstract Background Streptococcus pneumoniae is a major causative agent in community-acquired pneumonia and sepsis. Overwhelming lung inflammation during pneumococcal pneumonia may hamper lung function. Ibrutinib is an irreversible inhibitor of Bruto
Externí odkaz:
https://doaj.org/article/7cc2f9884a124007aa14943727f594cd
Autor:
Bernadette Schurink, PhD, Eva Roos, PhD, Teodora Radonic, PhD, Ellis Barbe, PhD, Catherine S C Bouman, PhD, Hans H de Boer, PhD, Godelieve J de Bree, PhD, Esther B Bulle, MD, Eleonora M Aronica, ProfPhD, Sandrine Florquin, ProfPhD, Judith Fronczek, PhD, Leo M A Heunks, ProfPhD, Menno D de Jong, ProfPhD, Lihui Guo, PhD, Romy du Long, MD, Rene Lutter, PhD, Pam C G Molenaar, BSc, E Andra Neefjes-Borst, MD, Hans W M Niessen, ProfPhD, Carel J M van Noesel, ProfPhD, Joris J T H Roelofs, PhD, Eric J Snijder, ProfPhD, Eline C Soer, PhD, Joanne Verheij, PhD, Alexander P J Vlaar, PhD, Wim Vos, MSc, Nicole N van der Wel, PhD, Allard C van der Wal, ProfPhD, Paul van der Valk, ProfPhD, Marianna Bugiani, PhD
Publikováno v:
The Lancet Microbe, Vol 1, Iss 7, Pp e290-e299 (2020)
Summary: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targets multiple organs and causes severe coagulopathy. Histopathological organ changes might not only be attributable to a direct virus-induced effect, but also the im
Externí odkaz:
https://doaj.org/article/9c826f4dae8a4c1993bc4d9880a5fd0c
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Renal ischemia reperfusion injury (IRI), a common event after renal transplantation, causes acute kidney injury (AKI), increases the risk of delayed graft function (DGF), primes the donor kidney for rejection, and contributes to the long-term risk of
Externí odkaz:
https://doaj.org/article/441201232f6f4ddb96d951d7717263a3