Výsledky vyhledávání - "Sandrine Fleury-Cappellesso"

Akademický článek

Biodistribution of Mesenchymal Stem/Stromal Cells in a Preclinical Setting

Autor: Luc Sensebé, Sandrine Fleury-Cappellesso

Publikováno v: Stem Cells International, Vol 2013 (2013)

Due to their multi/pluripotency and immunosuppressive properties, mesenchymal stem/stromal cells (MSCs) are important tools for treatment of immune disorders and tissue repair. The increasing uses of MSCs lead to the development of production process

Externí odkaz: https://doaj.org/article/a4772f7fbdf14a7f941cfe8e297a9baa

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Lack of anti-inflammatory and anti-catabolic effects on basal inflamed osteoarthritic chondrocytes or synoviocytes by adipose stem cell-conditioned medium

Autor: Christian Jorgensen, Elena Gabusi, Cristina Manferdini, Sandrine Fleury-Cappellesso, Danièle Noël, Francesca Paolella, Francesco Grassi, Marie Maumus, Gina Lisignoli

Publikováno v: Osteoarthritis and Cartilage
Osteoarthritis and Cartilage, Elsevier, 2015, 23 (11), pp.2045-2057. ⟨10.1016/j.joca.2015.03.025⟩

International audience; ObjectiveTo define whether good manufacturing practice (GMP)-clinical grade adipose stem cell (ASC)-derived conditioned medium (CM) is as effective as GMP-ASC in modulating inflammatory and catabolic factors released by both o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3eb172c88de3d0f740149d3fb36d23
https://doi.org/10.1016/j.joca.2015.03.025

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Epigenetic regulation of human adipose-derived stem cells differentiation

Autor: Inga Serenaite, Ausra Unguryte, Eiva Bernotiene, Roberta Misgirdaite, Kristina Daniunaite, Sandrine Fleury-Cappellesso, Sonata Jarmalaite, Juozas Gordevičius

Publikováno v: Molecular and Cellular Biochemistry. 410:111-120

Adult stem cells have more restricted differentiation potential than embryonic stem cells (ESCs), but upon appropriate stimulation can differentiate into cells of different germ layers. Epigenetic factors, including DNA modifications, take a signific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d99b33285566e38138a05d20e614885
https://doi.org/10.1007/s11010-015-2543-7

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Adipose stromal cells mediated switching of the pro-inflammatory profile of m1-like macrophages is facilitated by pge2: in vitro evaluation

Autor: Giuseppe Filardo, Mary Murphy, Elena Gabusi, Andrea Barbero, Cristina Manferdini, Francesca Paolella, Anna Piacentini, Sandrine Fleury-Cappellesso, Laura Gambari, Gina Lisignoli

Publikováno v: Osteoarthritis and Cartilage

Summary Objective To define if adipose mesenchymal stromal cell (ASC) treatment mediated switching of the pro-inflammatory profile of M1-like macrophages as a means to develop a tailored in vitro efficacy/potency test. Design We firstly performed imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2377a91c431ec6de118cb2d6dfb56314
http://hdl.handle.net/10379/12621

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AB0064 Adipose stromal cells exert specific effects on osteoarthritic synovial macrophages

Autor: Elena Gabusi, Andrea Barbero, Anna Piacentini, Gina Lisignoli, Sandrine Fleury-Cappellesso, Mary Murphy, Francesca Paolella, Laura Gambari, C. Manferdini

Publikováno v: Abstracts Accepted for Publication.

Background Osteoarthritis (OA) is the most common joint disease and the major cause of pain and disability in the aging population [1]. Adipose stromal cells (ASC) are promising candidate for cell therapy in OA, because they have immunomodulatory, tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2eb40f9ba9c5a3d9aa704a6f8a8da073
https://doi.org/10.1136/annrheumdis-2017-eular.6081

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Adipose-Derived Mesenchymal Stem Cells Exert Antiinflammatory Effects on Chondrocytes and Synoviocytes From Osteoarthritis Patients Through Prostaglandin E-2

Autor: Christian Jorgensen, Cristina Manferdini, Giuseppe Filardo, Philippe Bourin, Marie Maumus, Anna Piacentini, Andrea Facchini, Gina Lisignoli, Sandrine Fleury-Cappellesso, Julie-Anne Peyrafitte, Danièle Noël, Elena Gabusi

Publikováno v: Arthritis & Rheumatism; Vol 65
Arthritis & Rheumatism

Objective To examine the effect of different sources of Good Manufacturing Practice clinical grade adipose-derived mesenchymal stem cells (AD-MSCs) on inflammatory factors in osteoarthritic (OA) chondrocytes and synoviocytes. Methods AD-MSCs from inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed6fa4cb867f22e0ad209b0823308e8

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From osteoarthritic synovium to synovial-derived cells characterization: synovial macrophages are key effector cells

Autor: Elena Gabusi, Luca Cattini, Francesca Paolella, Cristina Manferdini, Sandrine Fleury-Cappellesso, Giuseppe Filardo, Laura Gambari, Ylenia Silvestri, Gina Lisignoli

Publikováno v: Arthritis Research & Therapy

Background The aim of the study was to characterize synovial cells from OA synovium with low-grade and moderate-grade synovitis and to define the role of synovial macrophages in cell culture. Methods Synovial tissue explants were analyzed for the exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2de8a7caba543e55db101f38dd98159
https://zenodo.org/record/59355

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Characterization of synovial-derived cells from ostheoarthritic synovium: evidence that macrophages are key effector cells

Autor: Francesca Paolella, Elena Gabusi, Gina Lisignoli, Luca Cattini, Laura Gambari, C. Manferdini, Sandrine Fleury-Cappellesso

Publikováno v: Osteoarthritis and Cartilage. 24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e3f399ce286c8046dac0f4a885af5e

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Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components

Autor: Anita Ignatius, Caroline Maurer, Markus Rojewski, Mélanie Gadelorge, Ramin Lotfi, Sandrine Fleury-Cappellesso, Julia Dausend, Volker Mailänder, Daniel Fürst, Philippe Bourin, Natalie Fekete, Luc Sensebé, Hubert Schrezenmeier

Publikováno v: Cytotherapy
Cytotherapy; Vol 14

Background aims The clinical use of human mesenchymal stromal cells (MSC) requires ex vivo expansion in media containing supplements such as fetal bovine serum or, alternatively, human platelet lysate (PL). Methods Platelet concentrates were frozen,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d4d07550db6dc5e36f7648e5a9b9ec
https://doi.org/10.3109/14653249.2012.655420

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A regulatory cross-talk between Vγ9Vδ2 T lymphocytes and mesenchymal stem cells

Autor: Ludovic Martinet, Mélanie Gadelorge, Sandrine Fleury-Cappellesso, Jean-Jacques Fournié, Rémy Poupot, Gilles Dietrich, Philippe Bourin

Publikováno v: European Journal of Immunology. 39:752-762

The physiological functions of human TCRVgamma9Vdelta2(+) gammadelta lymphocytes reactive to non-peptide phosphoantigens contribute to cancer immunosurveillance and immunotherapy. However, their regulation by mesenchymal stem cells (MSC), multipotent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::067b7e404b40a0de63bdc45aff68727a
https://doi.org/10.1002/eji.200838812

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