Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Sandrine Dulong"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 2, Pp 221-235 (2023)
Abstract Quantitative systems pharmacology holds the promises of integrating results from laboratory animals or in vitro human systems into the design of human pharmacokinetic/pharmacodynamic (PK/PD) models allowing for precision and personalized med
Externí odkaz:
https://doaj.org/article/a570f2d18ee8427eb86ec0c99b252c12
Autor:
Eva Hadadi, William Taylor, Xiao-Mei Li, Yetki Aslan, Marthe Villote, Julie Rivière, Gaelle Duvallet, Charlotte Auriau, Sandrine Dulong, Isabelle Raymond-Letron, Sylvain Provot, Annelise Bennaceur-Griscelli, Hervé Acloque
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Circadian disruption is implicated in the development of different human cancers. Here the authors show that chronic circadian disruption, through continuous jet lag, only moderately affects primary tumour growth but promotes cancer-cell disseminatio
Externí odkaz:
https://doaj.org/article/9351250a0e324fe7aa73022a4bbf04d5
Autor:
Sandrine Dulong, Lucas Eduardo Botelho de Souza, Jean Machowiak, Benoit Peuteman, Gaelle Duvallet, Déborah Boyenval, Elise Roth, Afag Asgarova, Yunhua Chang, Xiao-Mei Li, Adlen Foudi, Annabelle Ballesta
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2465 (2022)
Oxaliplatin was nearly twice as hematotoxic, with optimal circadian timing differing by 6 h, in women as compared to men with colorectal cancers. Hence, we investigated sex- and timing-related determinants of oxaliplatin hematopoietic toxicities in m
Externí odkaz:
https://doaj.org/article/4eb1871dcdec473f9e2220ee8b078af6
Autor:
Annabelle Ballesta, Sandrine Dulong, Chadi Abbara, Boris Cohen, Alper Okyar, Jean Clairambault, Francis Levi
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 9, p e1002143 (2011)
Circadian timing largely modifies efficacy and toxicity of many anticancer drugs. Recent findings suggest that optimal circadian delivery patterns depend on the patient genetic background. We present here a combined experimental and mathematical appr
Externí odkaz:
https://doaj.org/article/2c16131466da4f039d02a5470af19687
The supplementary file reports the dynamic of nuclear TOP1 protein expression in Caco-2 cells (Figure S1), the circadian parameter values for clock and irinotecan metabolism gene mRNA expressions in synchronized Caco-2 cells (Table S1), the model-pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78242e06fbdc88a864f93e64b01db9a8
https://doi.org/10.1158/1535-7163.22501867.v1
https://doi.org/10.1158/1535-7163.22501867.v1
Autor:
Francis Lévi, Franck Delaunay, Catherine Guettier, Francesco Scaglione, Ali Mteyrek, Sandrine Siffroi-Fernandez, Elisabeth Filipski, Sandrine Dulong, Mircea Dumitru, Ali Mohammad-Djafari, Xiao-Mei Li
PDF file - 110K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17e1e23f0ca899b4c1f428bb44c0797
https://doi.org/10.1158/0008-5472.22400334
https://doi.org/10.1158/0008-5472.22400334
Autor:
Francis Lévi, Franck Delaunay, Catherine Guettier, Francesco Scaglione, Ali Mteyrek, Sandrine Siffroi-Fernandez, Elisabeth Filipski, Sandrine Dulong, Mircea Dumitru, Ali Mohammad-Djafari, Xiao-Mei Li
PDF file - 78K, Plasma pharmacokinetic parameters (Mean plus/minus SEM) of irinotecan according to timing and chronotoxicity classes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab897210d521144a2929715c6f47598d
https://doi.org/10.1158/0008-5472.22400328.v1
https://doi.org/10.1158/0008-5472.22400328.v1
Autor:
Francis Lévi, Franck Delaunay, Catherine Guettier, Francesco Scaglione, Ali Mteyrek, Sandrine Siffroi-Fernandez, Elisabeth Filipski, Sandrine Dulong, Mircea Dumitru, Ali Mohammad-Djafari, Xiao-Mei Li
PDF file - 78K, Plasma pharmacokinetic parameters (Mean plus/minus SEM) of irinotecan bioactive metabolite SN-38 according to timing and chronotoxicity classes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e73855f407dc5a2521259abd9616c3b
https://doi.org/10.1158/0008-5472.22400325
https://doi.org/10.1158/0008-5472.22400325
Autor:
Francis Lévi, Franck Delaunay, Catherine Guettier, Francesco Scaglione, Ali Mteyrek, Sandrine Siffroi-Fernandez, Elisabeth Filipski, Sandrine Dulong, Mircea Dumitru, Ali Mohammad-Djafari, Xiao-Mei Li
PDF file - 251K, Discriminating chronotoxicity Classes based on selected circadian mRNA gene expressions in liver and colon mucosa.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99040ad1c33d25a0439549f902b12e42
https://doi.org/10.1158/0008-5472.22400337.v1
https://doi.org/10.1158/0008-5472.22400337.v1
Autor:
Francis Lévi, Franck Delaunay, Catherine Guettier, Francesco Scaglione, Ali Mteyrek, Sandrine Siffroi-Fernandez, Elisabeth Filipski, Sandrine Dulong, Mircea Dumitru, Ali Mohammad-Djafari, Xiao-Mei Li
PDF file - 85K, Scheme of the mathematical model, describing the linear relation between input data (mRNA expression of Rev-erbalpha and Bmal1) and output data (body weight loss - BWL).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e67d40c5af966b7c4d48bd9516a5a2
https://doi.org/10.1158/0008-5472.22400346.v1
https://doi.org/10.1158/0008-5472.22400346.v1