Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sandrine Billet"'
Autor:
Hayato Muranaka, Rasaq Akinsola, Sandrine Billet, Stephen J. Pandol, Andrew E. Hendifar, Neil A. Bhowmick, Jun Gong
Publikováno v:
Cancers, Vol 16, Iss 5, p 1057 (2024)
Glutamine, a multifaceted nonessential/conditionally essential amino acid integral to cellular metabolism and immune function, holds pivotal importance in the landscape of cancer therapy. This review delves into the intricate dynamics surrounding bot
Externí odkaz:
https://doaj.org/article/b08086427bc549ffaa89132e0e2772eb
Autor:
Le Zhang, Yueyuan Zheng, Wenwen Chien, Benjamin Ziman, Sandrine Billet, H. Phillip Koeffler, De-Chen Lin, Neil A. Bhowmick
Publikováno v:
Cancers, Vol 15, Iss 22, p 5377 (2023)
ARID1A, a member of the chromatin remodeling SWI/SNF complex, is frequently lost in many cancer types, including esophageal adenocarcinoma (EAC). Here, we study the impact of ARID1A deficiency on the anti-tumor immune response in EAC. We find that EA
Externí odkaz:
https://doaj.org/article/528d9206b84940d583e41306da8ecfcd
Autor:
Jun Gong, Arsen Osipov, Jeremy Lorber, Mourad Tighiouart, Albert K. Kwan, Hayato Muranaka, Rasaq Akinsola, Sandrine Billet, Abrahm Levi, Anser Abbas, John Davelaar, Neil Bhowmick, Andrew E. Hendifar
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1392 (2023)
Advanced pancreatic cancer is underscored by progressive therapeutic resistance and a dismal 5-year survival rate of 3%. Preclinical data demonstrated glutamine supplementation, not deprivation, elicited antitumor effects against pancreatic ductal ad
Externí odkaz:
https://doaj.org/article/f0b25285990f44ef9808c8aef61b701a
Autor:
Chuanxia Liu, Sandrine Billet, Diptiman Choudhury, Ran Cheng, Subhash Haldar, Ana Fernandez, Shea Biondi, Zhenqiu Liu, Hongmei Zhou, Neil A. Bhowmick
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 118-128 (2021)
Head and neck cancers are often diagnosed at later stages with poor outcomes. Mesenchymal stem cells (MSC) are recruited to primary tumor sites where they can have pro- and antitumorigenic influence. In trying to better understand the dynamics betwee
Externí odkaz:
https://doaj.org/article/6934fb604ca443929a6626177a632bc6
Fatty Acid Signaling Impacts Prostate Cancer Lineage Plasticity in an Autocrine and Paracrine Manner
Autor:
Le Zhang, Sandrine Billet, Gabrielle Gonzales, Krizia Rohena-Rivera, Hayato Muranaka, Gina Chia-Yi Chu, Qian Yang, Hyung Kim, Neil A. Bhowmick, Bethany Smith
Publikováno v:
Cancers, Vol 14, Iss 14, p 3449 (2022)
Prostate cancer (PCa) affects an estimated 250,000 men every year and causes 34,000 deaths annually. A high-fat diet and obesity are associated with PCa progression and mortality. This study’s premise was the novel observation of crosstalk between
Externí odkaz:
https://doaj.org/article/adcd856a061b443390e40ac582a75603
Publikováno v:
Cancers, Vol 14, Iss 10, p 2491 (2022)
Nearly half of localized prostate cancer (PCa) patients given radiation therapy develop recurrence. Here, we identified glutamine as a key player in mediating the radio-sensitivity of PCa. Glutamine transporters and glutaminase are upregulated by rad
Externí odkaz:
https://doaj.org/article/340de3f1c8d64039badc6d16f4125e67
Autor:
Ahmed F. Salem, Luca Gambini, Sandrine Billet, Yu Sun, Hiromichi Oshiro, Ming Zhao, Robert M. Hoffman, Neil A. Bhowmick, Maurizio Pellecchia
Publikováno v:
Cancers, Vol 12, Iss 10, p 2854 (2020)
The EphA2 tyrosine kinase receptor is highly expressed in several types of solid tumors. In our recent studies, we targeted EphA2 in pancreatic cancer with agonistic agents and demonstrated that suppression of EphA2 significantly reduced cancer-cell
Externí odkaz:
https://doaj.org/article/8e9066496546453eb688566fa9d45150
Autor:
Zhijun Wang, So Yeon Kim, Wei Tu, Jieun Kim, Alexander Xu, Yoon Mee Yang, Michitaka Matsuda, Lien Reolizo, Takashi Tsuchiya, Sandrine Billet, Alexandra Gangi, Mazen Noureddin, Ben A. Falk, Sungjin Kim, Wei Fan, Mourad Tighiouart, Sungyong You, Michael S. Lewis, Stephen J. Pandol, Dolores Di Vizio, Akil Merchant, Edwin M. Posadas, Neil A. Bhowmick, Shelly C. Lu, Ekihiro Seki
Publikováno v:
Cell Metabolism.
Autor:
Maurizio Pellecchia, Paul B. Fisher, Elena B. Pasquale, Shinichi Kitada, Neil A. Bhowmick, Ana Fernandez, Sandrine Billet, Sayantan Mitra, Bainan Wu, Ziming Zhang, Swadesh Das, John L. Stebbins, Roberta Noberini, Si Wang
PDF file - 328K, Scheme 1. Synthesis of YNH motif and dYNH motif Scheme S2. Synthetic route for YSA-PTX Figure S1. In vivo prostate cancer xenograft studies. Figure S2. EphA2 expression in RENCA renal carcinoma cells and PC3M prostate cancer cells. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d69e65203ba867b59145059bb021e77
https://doi.org/10.1158/1078-0432.22446387.v1
https://doi.org/10.1158/1078-0432.22446387.v1
Autor:
Maurizio Pellecchia, Paul B. Fisher, Elena B. Pasquale, Shinichi Kitada, Neil A. Bhowmick, Ana Fernandez, Sandrine Billet, Sayantan Mitra, Bainan Wu, Ziming Zhang, Swadesh Das, John L. Stebbins, Roberta Noberini, Si Wang
Purpose: YSA is an EphA2-targeting peptide that effectively delivers anticancer agents to prostate cancer tumors. Here, we report on how we increased the drug-like properties of this delivery system.Experimental Design: By introducing non-natural ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058e0bf87b375d073d5ba1bd8ddba197
https://doi.org/10.1158/1078-0432.c.6520734
https://doi.org/10.1158/1078-0432.c.6520734