Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Sandrine Py"'
Autor:
Alexis Vallée, Jean-Luc Vasse, Jean-Bernard Behr, Sandrine Py, Fabien Massicot, Gatien Messire
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2019, 17 (29), pp.7066-7077. ⟨10.1039/c9ob01419e⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2019, 17 (29), pp.7066-7077. ⟨10.1039/c9ob01419e⟩
International audience; The synthesis of unprecedented branched pyrrolizidines and indolizidines was accomplished via nitrone chemistry. The required ketonitrone, a known intermediate usually obtained as a mixture of regioisomers, was prepared in a p
Autor:
Sandrine Py, Arnaud Martel, Sullivan Bricaud, Romain Ligny, Sopa Chewchanwuttiwong, Mathieu Y. Laurent, Rawan Hadade, Corentin Jacquemmoz, Jérôme Lhoste, Gilles Dujardin, X. M. Zhang
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2021, 86 (12), pp.8041-8055. ⟨10.1021/acs.joc.1c00456⟩
Journal of Organic Chemistry, American Chemical Society, 2021, 86 (12), pp.8041-8055. ⟨10.1021/acs.joc.1c00456⟩
International audience; Enantiopure (R) and (S) cyclic α,α-disubstituted amino acid derivatives displaying a δ-valerolactam side chain were prepared from a common isoxazolidine precursor. The (R)-configured δ-valerolactam 11 was converted into di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e826de34a7c03cd5e2e67830f19b1162
https://hal.univ-grenoble-alpes.fr/hal-03371450/document
https://hal.univ-grenoble-alpes.fr/hal-03371450/document
Publikováno v:
European Journal of Organic Chemistry. 2018:2178-2192
Autor:
Salia Tangara, Christian Philouze, Jean-Bernard Behr, Sandrine Py, Alice Kanazawa, Martine Fayolle, Jean-François Poisson
Publikováno v:
New Journal of Chemistry. 42:16735-16743
The synthesis of the peracetylated ketonitrone 4 is described in four steps from L-sorbose. This cyclic nitrone is crystalline and proved to preferentially adopt a 4H3 conformation with all acetate groups in pseudo-axial orientation. Nitrone 4 underg
Publikováno v:
European Journal of Organic Chemistry. 2017:6357-6364
The Baldwin rearrangement is a thermally induced ring contraction of 4-isoxazolines into 2-acylaziridines. The reaction yields highly strained nitrogen-containing three-membered-ring compounds from readily available five-membered N-O heterocycles. Di
Publikováno v:
European Journal of Organic Chemistry. 2016:4003-4012
Upon treatment of fructose-derived nitrone 1 with samarium diiodide, with the aim of inducing its umpolung and coupling with electrophiles, an unexpected β-elimination of the benzyloxy group at C-1 was observed, yielding nitrone 2. The mechanism and
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2015, 21 (27), pp.9753-9768. ⟨10.1002/chem.201500587⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2015, 21 (27), pp.9753-9768. ⟨10.1002/chem.201500587⟩
A DFT study of the reaction mechanism of the rhodium-catalysed enantioselective arylation of (E)-N-propylidene-4-methyl-benzenesulfonamide by phenylboronic acid [Lin et al J. Am. Chem. Soc. 2011, 133, 12394] is reported. The catalyst ([{Rh(OH)(dien
Publikováno v:
Organic Letters
Organic Letters, American Chemical Society, 2017, 19 (18), pp.4842-4845. ⟨10.1021/acs.orglett.7b02283⟩
Organic Letters, American Chemical Society, 2017, 19 (18), pp.4842-4845. ⟨10.1021/acs.orglett.7b02283⟩
Rare C-7-substituted aziridinyl iminosugars can be synthesized through a short reaction sequence involving 1,3-cycloaddition of cyclic nitrones with alkynes and a Baldwin rearrangement of isoxazolines into bicyclic 2-acylaziridines. The method is eff
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2017, 82 (18), pp.9866-9872. ⟨10.1021/acs.joc.7b01494⟩
Journal of Organic Chemistry, American Chemical Society, 2017, 82 (18), pp.9866-9872. ⟨10.1021/acs.joc.7b01494⟩
Polyhydroxylated quinolizidines bearing a hydroxymethyl group at the ring junction were synthesized from a readily available l-sorbose-derived ketonitrone. Evaluated as glycoside hydrolase inhibitors, these quinolizidines revealed to be potent and se
Autor:
Kawther Ben Ayed, Arnaud Martel, Jean-François Poisson, Houcine Ammar, Souhir Abid, Mathieu Y. Laurent, Gilles Dujardin, Anne Beauchard, Sandrine Py
Publikováno v:
European Journal of Organic Chemistry. 2014:2924-2932
Enantiopure vinyl ethers of Stericol® underwent diastereoselective thermal 1,3 dipolar cycloadditions with N-benzyl, N-benzhydryl, and N-PMB aspartate ester nitrones. Chemoselective N-debenzylation of the resulting cycloadducts afforded diastereomer