Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Sandrine, Delignat"'
Autor:
Melissa Bou-Jaoudeh, Sandrine Delignat, Victoria Daventure, Jan Astermark, Hervé Lévesque, Jordan D. Dimitrov, Claire Deligne, Valérie Proulle, Sébastien Lacroix-Desmazes
Publikováno v:
Haematologica, Vol 108, Iss 5 (2023)
Neutralizing anti-factor VIII (FVIII) antibodies, known as FVIII inhibitors, represent a major drawback of replacement therapy in persons with congenital hemophilia A (PwHA), rendering further infusions of FVIII ineffective. FVIII inhibitors can also
Externí odkaz:
https://doaj.org/article/9ef633a3841246aeb61a09081db47918
Autor:
Sébastien Sanges, Emmanuelle Jeanpierre, Benjamin Lopez, Jules Russick, Sandrine Delignat, Benjamin Carpentier, Romain Dubois, Sylvain Dubucquoi, Thomas Guerrier, Éric Hachulla, Pierre-Yves Hatron, Camille Paris, Sophie Susen, David Launay, Sébastien Lacroix-Desmazes, Louis Terriou
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
We report the observation of a 75-year-old patient referred for cervical lymphadenopathies. A pre-lymphadenectomy blood work revealed an asymptomatic elevation of aPTT with low factor VIII (FVIII) levels and high anti-FVIII antibodies titers, consist
Externí odkaz:
https://doaj.org/article/1b6970b449e8410cacb5990620606d4c
Autor:
Angelina Mimoun, Sandrine Delignat, Ivan Peyron, Victoria Daventure, Maxime Lecerf, Jordan D. Dimitrov, Srinivas V. Kaveri, Jagadeesh Bayry, Sébastien Lacroix-Desmazes
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In humans, maternal IgGs are transferred to the fetus from the second trimester of pregnancy onwards. The transplacental delivery of maternal IgG is mediated by its binding to the neonatal Fc receptor (FcRn) after endocytosis by the syncytiotrophobla
Externí odkaz:
https://doaj.org/article/3421ad713d204e8993d9550f66c0aef8
Autor:
Jules Russick, Sandrine Delignat, Peter Milanov, Olivier Christophe, Gábor Boros, Cécile V. Denis, Peter J. Lenting, Srinivas V. Kaveri, Sébastien Lacroix-Desmazes
Publikováno v:
Haematologica, Vol 105, Iss 4 (2020)
The treatment or prevention of bleeding in patients with hemophilia A relies on replacement therapy with different factor VIII (FVIII)-containing products or on the use of by-passing agents, i.e., activated prothrombin complex concentrates or recombi
Externí odkaz:
https://doaj.org/article/e96bd6a875854068959fee796f33b28e
Autor:
Sandrine Delignat, Julie Rayes, Suryasarathi Dasgupta, Bagirath Gangadharan, Cécile V. Denis, Olivier D. Christophe, Jagadeesh Bayry, Srinivas V. Kaveri, Sébastien Lacroix-Desmazes
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The development of an immune response against therapeutic factor VIII is the major complication in hemophilia A patients. Oligomannose carbohydrates at N239 and/or N2118 on factor VIII allow its binding to the macrophage mannose receptor expressed on
Externí odkaz:
https://doaj.org/article/56cbe631476a4dda8386f9a407c8d613
Autor:
Sandrine Delignat, Jules Russick, Bagirath Gangadharan, Julie Rayes, Mathieu Ing, Jan Voorberg, Srinivas V. Kaveri, Sébastien Lacroix-Desmazes
Publikováno v:
Haematologica, Vol 104, Iss 5 (2019)
Hemophilia A is a rare hemorrhagic disorder caused by the lack of functional pro-coagulant factor VIII. Factor VIII replacement therapy in patients with severe hemophilia A results in the development of inhibitory anti-factor VIII IgG in up to 30% of
Externí odkaz:
https://doaj.org/article/497a1764d881450494885fc6b6e0fcf9
Autor:
Julie Rayes, Mathieu Ing, Sandrine Delignat, Ivan Peyron, Laurent Gilardin, Carl-Wilhelm Vogel, David C. Fritzinger, Véronique Frémeaux-Bacchi, Srinivas V. Kaveri, Lubka T. Roumenina, Sébastien Lacroix-Desmazes
Publikováno v:
Haematologica, Vol 103, Iss 2 (2018)
Development of neutralizing antibodies against therapeutic Factor VIII (FVIII) is the most serious complication of the treatment of hemophilia A. There is growing evidence to show the multifactorial origin of the anti-FVIII immune response, combining
Externí odkaz:
https://doaj.org/article/cc98a30f33fa45909baf300025741a38
Autor:
Laurent Gilardin, Sandrine Delignat, Ivan Peyron, Mathieu Ing, Yu-Chun Lone, Bagirath Gangadharan, Baptiste Michard, Yousra Kherabi, Meenu Sharma, Anastas Pashov, Jean-Baptiste Latouche, Mohamad Hamieh, Olivier Toutirais, Pascale Loiseau, Lionel Galicier, Agnès Veyradier, Srini Kaveri, Bernard Maillère, Paul Coppo, Sébastien Lacroix-Desmazes
Publikováno v:
Haematologica, Vol 102, Iss 11 (2017)
Acquired thrombotic thrombocytopenic purpura is a rare and severe disease characterized by auto-antibodies directed against “A Disintegrin And Metalloproteinase with Thrombospondin type 1 repeats, 13th member" (ADAMTS13), a plasma protein involved
Externí odkaz:
https://doaj.org/article/80814320e5c548d78a1e434443f0aa11
Autor:
Bagirath Gangadharan, Mathieu Ing, Sandrine Delignat, Ivan Peyron, Maud Teyssandier, Srinivas V. Kaveri, Sébastien Lacroix-Desmazes
Publikováno v:
Haematologica, Vol 102, Iss 2 (2017)
The development of inhibitory antibodies to therapeutic factor VIII is the major complication of replacement therapy in patients with hemophilia A. The first step in the initiation of the anti-factor VIII immune response is factor VIII interaction wi
Externí odkaz:
https://doaj.org/article/9ebd496e0534438787f8552fd1754402
Autor:
H. De Boysson, Anupama Karnam, Mikael Ebbo, Samuel Deshayes, Laurent Magy, Alexandre Nguyen, Sébastien Lacroix-Desmazes, G. Maigné, Jagadeesh Bayry, Sandrine Delignat, Y. Repesse, Jean-Michel Vallat, Olivier Benveniste, Yves Allenbach, Achille Aouba
Publikováno v:
Clinical and Experimental Immunology
Clinical and Experimental Immunology, 2021, 204 (2), pp.258-266. ⟨10.1111/cei.13580⟩
Clin Exp Immunol
Clinical and Experimental Immunology, 2021, 204 (2), pp.258-266. ⟨10.1111/cei.13580⟩
Clin Exp Immunol
SummaryThe mechanisms of action of intravenous immunoglobulins (IVIg) in autoimmune diseases are not fully understood. The fixed duration of efficacy and noncumulative effects of IVIg in immune thrombocytopenia (ITP) and acquired von Willebrand disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d770561c0595c6dc462313d9854452
https://doi.org/10.1111/cei.13580
https://doi.org/10.1111/cei.13580