Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sandrina, Phipps"'
Autor:
Peter Zanvit, Dewald van Dyk, Christine Fazenbaker, Kelly McGlinchey, Weichuan Luo, Jessica M. Pezold, John Meekin, Chien-ying Chang, Rosa A. Carrasco, Shannon Breen, Crystal Sao-Fong Cheung, Ariel Endlich-Frazier, Benjamin Clark, Nina J. Chu, Alessio Vantellini, Philip L. Martin, Clare E. Hoover, Kenesha Riley, Steve M. Sweet, David Chain, Yeoun Jin Kim, Eric Tu, Nathalie Harder, Sandrina Phipps, Melissa Damschroder, Ryan N. Gilbreth, Mark Cobbold, Gordon Moody, Emily E. Bosco
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
Prostate cancer is generally considered an immunologically “cold” tumor type that is insensitive to immunotherapy. Targeting surface antigens on tumors through cellular therapy can induce a potent antitumor immune response to “heat up” the tu
Externí odkaz:
https://doaj.org/article/e772d4b790a848fcb94aa4259efad645
Autor:
Jay Harper, Mark Cobbold, David A. Tice, Philip W. Howard, Ronald Herbst, Herren Wu, Changshou Gao, Luke A. Masterson, Kimberly Cook, Kathryn Pugh, Susan Wilson, Nazzareno Dimasi, Jens-Oliver Koopmann, Sonja Hess, Ryan Fleming, Sandrina Phipps, Allison M. Barrett, Hong Chen, Andrew Garcia, Gina D’Angelo, Wen Yu, Raghothama Chaerkady, Shenlan Mao
The addition of the ATR inhibitor, AZD6738, did not show synergistic cytotoxicity with SG3199 or ADCs in parental MDA-MB-361 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d95af0ffa8c167232f6d1a26846154
https://doi.org/10.1158/1535-7163.22521297.v1
https://doi.org/10.1158/1535-7163.22521297.v1
Autor:
Jay Harper, Mark Cobbold, David A. Tice, Philip W. Howard, Ronald Herbst, Herren Wu, Changshou Gao, Luke A. Masterson, Kimberly Cook, Kathryn Pugh, Susan Wilson, Nazzareno Dimasi, Jens-Oliver Koopmann, Sonja Hess, Ryan Fleming, Sandrina Phipps, Allison M. Barrett, Hong Chen, Andrew Garcia, Gina D’Angelo, Wen Yu, Raghothama Chaerkady, Shenlan Mao
Differentially expressed proteins identified in the 361-PBDr cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c24ef074a6decab4f3756699682b81e
https://doi.org/10.1158/1535-7163.22521276.v1
https://doi.org/10.1158/1535-7163.22521276.v1
Autor:
David A. Tice, Philip W. Howard, Ronald Herbst, Kenneth C. Anderson, Luke Masterson, Michael J. Wick, Stephen J. Gregson, Sriram Sridhar, Kyriakos P. Papadopoulos, Alyssa Moriarty, Nazzareno Dimasi, Marlon C. Rebelatto, Christine Mione Kiefer, Sandrina Phipps, Yu-Tzu Tai, Arnaud C. Tiberghien, John Meekin, Krista Kinneer
Purpose:Antibody–drug conjugates (ADC) utilizing noncleavable linker drugs have been approved for clinical use, and several are in development targeting solid and hematologic malignancies including multiple myeloma. Currently, there are no reliable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80839c279aab8bddbee384f0cdadbd2b
https://doi.org/10.1158/1078-0432.c.6527396.v1
https://doi.org/10.1158/1078-0432.c.6527396.v1
Autor:
David A. Tice, Philip W. Howard, Ronald Herbst, Kenneth C. Anderson, Luke Masterson, Michael J. Wick, Stephen J. Gregson, Sriram Sridhar, Kyriakos P. Papadopoulos, Alyssa Moriarty, Nazzareno Dimasi, Marlon C. Rebelatto, Christine Mione Kiefer, Sandrina Phipps, Yu-Tzu Tai, Arnaud C. Tiberghien, John Meekin, Krista Kinneer
Supplementary methods and materials, and Supplemental Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f906385187323fe823fa7c557d5fdaf
https://doi.org/10.1158/1078-0432.22469939
https://doi.org/10.1158/1078-0432.22469939
Autor:
David A. Tice, Philip W. Howard, Ronald Herbst, Kenneth C. Anderson, Luke Masterson, Michael J. Wick, Stephen J. Gregson, Sriram Sridhar, Kyriakos P. Papadopoulos, Alyssa Moriarty, Nazzareno Dimasi, Marlon C. Rebelatto, Christine Mione Kiefer, Sandrina Phipps, Yu-Tzu Tai, Arnaud C. Tiberghien, John Meekin, Krista Kinneer
Supplementary table showing the relative expression of 43 target genes in a panel of EphA2-positive cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656bb05d0a44970a8add94d9221308b0
https://doi.org/10.1158/1078-0432.22469936.v1
https://doi.org/10.1158/1078-0432.22469936.v1
Autor:
Luke A. Masterson, Sonja Hess, Howard Philip Wilson, Andrew Garcia, Kimberly M Cook, Kathryn M. Pugh, Wen Yu, Hong Chen, Allison M. Barrett, Ronald Herbst, Shenlan Mao, Changshou Gao, David A. Tice, Mark Cobbold, Herren Wu, Jens-Oliver Koopmann, Ryan Fleming, Jay Harper, Susan Wilson, Raghothama Chaerkady, Gina DAngelo, Sandrina Phipps, Nazzareno Dimasi
Publikováno v:
Molecular cancer therapeutics. 20(3)
Resistance to antibody–drug conjugates (ADCs) has been observed in both preclinical models and clinical studies. However, mechanisms of resistance to pyrrolobenzodiazepine (PBD)-conjugated ADCs have not been well characterized and thus, this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f8ba1b938a0c38d60da28cc5a618737
https://pubmed.ncbi.nlm.nih.gov/33653945
https://pubmed.ncbi.nlm.nih.gov/33653945
Autor:
John Meekin, Haihong Zhong, Maureen Kennedy, Rosa A. Carrasco, Ronald Herbst, Sandrina Phipps, Binyam Bezabeh, R. James Christie, Karma Dacosta, David A. Tice, Emily E. Bosco, Jiping Zha, Rakesh Dixit, Partha S. Chowdhury, Joanne Ayriss, Qun Du, Zhan Xiao, Darrin Sabol, MaryJane Hinrichs, Cui Chen, Shannon Breen, Lee Brown, Molly Reed
Publikováno v:
Oncotarget
Despite recent advances in treatment, breast cancer remains the second-most common cause of cancer death among American women. A greater understanding of the molecular characteristics of breast tumors could ultimately lead to improved tumor-targeted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ad154b2ef7e44c63da1dd1a359911a
https://doi.org/10.18632/oncotarget.25160
https://doi.org/10.18632/oncotarget.25160
Autor:
Daniel R. Higazi, Michael A. Bowen, Nicholas J. Bond, Rebecca Dunmore, Lynne Murray, William Dall'acqua, Yanli Wu, Jie Zhu, Toyin Kasali, M. Jack Borrok, Lena Shirinian, Arnita Barnes, Catherine Huntington, Sandrina Phipps, John Hood, Emilie Solier, Ping Tsui, Keith W Rickert, Alan M. Carruthers
Publikováno v:
mAbs. 9:104-113
Excessive transforming growth factor (TGF)-β is associated with pro-fibrotic responses in lung disease, yet it also plays essential roles in tissue homeostasis and autoimmunity. Therefore, selective inhibition of excessive and aberrant integrin-medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d570ca136c988614413eb835598fa70
https://doi.org/10.1080/19420862.2016.1255390
https://doi.org/10.1080/19420862.2016.1255390
Autor:
Anthony Shannon, Arnita Barnes, Susan Wilson, Caroline Kittinger, Ellen O'Connor, Robert Stadelman, Sandrina Phipps, Alan K. Hunter, LeeAnn Machiesky
Publikováno v:
Protein Expression and Purification. 167:105528
Interferon-alpha receptor 1 (IFNAR1) is a target of interest for recombinant biotherapeutics that block the JAK/STAT pathway. This pathway is believed to play a role in many diseases including Hepatitis B and C, Herpes Simplex, Multiple Sclerosis, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010b23d0fc456a8b5fdafd0a3e5b803b
https://doi.org/10.1016/j.pep.2019.105528
https://doi.org/10.1016/j.pep.2019.105528