Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Sandrin Garcia, P."'
Autor:
Isaura Isabelle Fonseca Gomes da Silva, Denise de Queiroga Nascimento, Alexandre Domingues Barbosa, Fabricio Oliveira Souto, Maria de Mascena Diniz Maia, Sergio Crovella, Paulo Roberto Eleuterio de Souza, Paula Sandrin-Garcia
Publikováno v:
Genetics and Molecular Biology, Vol 47, Iss 2 (2024)
Abstract We predicted miRNAs with regulatory impact on NFKB1 and TRAF6 gene expression and selected the miR-194-5p, miR-124-3p, miR-9-5p, and miR-340-5p and their target genes for expression analyses on CD14+ monocytes from rheumatoid arthritis (RA)
Externí odkaz:
https://doaj.org/article/566c607634db470993a290283a310f08
Autor:
Werbson Lima Guaraná, Camilla Albertina Dantas Lima, Alexandre Domingues Barbosa, Sergio Crovella, Paula Sandrin-Garcia
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5623 (2024)
Aminobisphosphonates (NBPs) are the first-choice medication for osteoporosis (OP); NBP treatment aims at increasing bone mineral density (BMD) by inhibiting the activity of farnesyl diphosphate synthase (FDPS) enzyme in osteoclasts. Despite its effic
Externí odkaz:
https://doaj.org/article/56868c4c6f3e4cd287eda3715c07455d
Autor:
Denise de Queiroga Nascimento, Isaura Isabelle Fonseca Gomes da Silva, Camilla Albertina Dantas Lima, André de Souza Cavalcanti, Luciana Rodrigues Roberti, Rosane Gomes de Paula Queiroz, Virginia Paes Leme Ferriani, Sergio Crovella, Luciana Martins de Carvalho, Paula Sandrin-Garcia
Publikováno v:
Autoimmunity, Vol 55, Iss 8, Pp 515-519 (2022)
Childhood- onset systemic lupus erythematosus (cSLE) is a multisystem inflammatory disease that can lead to severe clinical conditions resulting in early comorbidities. Several genetic, environmental, and immunological factors are known to influence
Externí odkaz:
https://doaj.org/article/b1a8f4212e324fbca6798eeb86cd51d9
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Alessandra Tesser, Luciana Martins de Carvalho, Paula Sandrin-Garcia, Alessia Pin, Serena Pastore, Andrea Taddio, Luciana Rodrigues Roberti, Rosane Gomes de Paula Queiroz, Virginia Paes Leme Ferriani, Sergio Crovella, Alberto Tommasini
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-12 (2020)
Abstract Background Systemic lupus erythematosus (SLE) is a complex multi-system disease, characterized by both autoimmune and autoinflammatory clinical and laboratory features. The role of type I interferon (IFN) in SLE has been demonstrated from th
Externí odkaz:
https://doaj.org/article/c7d7d03faa174dbda6b31e469d4fd616
Autor:
Isaura Isabelle Fonseca Gomes da Silva, Camilla Albertina Dantas Lima, Maria Larissa Andrade Monteiro, Daniella Alves Silva Pimentel Barboza, Eliezer Rushansky, Maria Helena Queiroz de Araújo Mariano, Paula Sandrin-Garcia, Paulo Roberto Eleutério de Souza, Maria de Mascena Diniz Maia
Publikováno v:
Autoimmunity, Vol 53, Iss 2, Pp 95-101 (2020)
Rheumatoid arthritis (RA) is an autoimmune disease which can lead to progressive and functional disability. Literature data suggest that some inflammatory proteins are dysregulated in RA patients and its genetic polymorphisms may contribute to the ae
Externí odkaz:
https://doaj.org/article/1035dae2b3554601bd7443bd2ee21635
Autor:
Catarina Addobbati Jordão Cavalcanti, Vanessa Germoglio, Jaqueline de Azevêdo Silva, Nadine Glesse, Priscila Vianna, Giovana Cechim, Odirlei Andre Monticielo, Ricardo Machado Xavier, João Carlos Tavares Brenol, Claiton Viegas Brenol, Thiago Sotero Fragoso, Alexandre Domingues Barbosa, Ângela Luiza Branco Pinto Duarte, Renê Donizeti Ribeiro Oliveira, Paulo Louzada-Júnior, Eduardo Antônio Donadi, José Artur Bogo Chies, Sergio Crovella, Paula Sandrin-Garcia
Publikováno v:
Autoimmunity, Vol 53, Iss 2, Pp 65-70 (2020)
The aim of the present study was to evaluate the impact of SEMA4A genetic variants on expression of sema4A protein and its relation to autoimmunity development in Systemic Lupus Erythematosus and Rheumatoid Arthritis patients. A total of 541 SLE pati
Externí odkaz:
https://doaj.org/article/b710504c7eb64163b8ae7fe6126d6183
Autor:
Luana Oliveira dos Santos, Adriana Valéria Sales Bispo, Juliana Vieira de Barros, Raysa Samanta Moraes Laranjeira, Rafaella do Nascimento Pinto, Jaqueline de Azevêdo Silva, Andréa de Rezende Duarte, Jacqueline Araújo, Paula Sandrin-Garcia, Sergio Crovella, Marcos André Cavalcanti Bezerra, Taciana Furtado de Mendonça Belmont, Maria do Socorro Cavalcanti, Neide Santos
Publikováno v:
Genetics and Molecular Biology, Vol 41, Iss 4, Pp 727-734 (2018)
Abstract Turner syndrome (TS) is characterized by a set of clinical conditions, including autoimmune/inflammatory diseases and infectious conditions, that can compromise a patient’s quality of life. Here we assessed polymorphisms in CTLA-4 +49A/G (
Externí odkaz:
https://doaj.org/article/b2e74d74f8134dda8a2786d07b465466
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12476 (2021)
Lupus nephritis (LN) is the most frequent and severe of systemic lupus erythematosus (SLE) clinical manifestations and contributes to the increase of morbidity and mortality of patients due to chronic kidney disease. The NLRP3 (NLR pyrin domain conta
Externí odkaz:
https://doaj.org/article/8874314f8c4444a39e4cbe2f64dfd88f