Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sandra Y. Flores"'
Autor:
Beverly P. Holskin, Sheryl L. Meyer, Emmanuel Burgeon, Bruce Jones, Thao Ung, Emir Duzic, Sandra Y. Flores, Mark A. Ator, Vincent J. Dupriez
Publikováno v:
Analytical Biochemistry. 400:184-189
Assay technologies that measure intracellular Ca 2+ release are among the predominant methods for evaluation of GPCR function. These measurements have historically been performed using cell-permeable fluorescent dyes, although the use of the recombin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f49fbd3b900603f3b6fc127c513e764
https://doi.org/10.1016/j.ab.2010.01.028
https://doi.org/10.1016/j.ab.2010.01.028
Autor:
Johannes Loffing, Nicole Siegrist, Daniel Sauter, Dominique Loffing-Cueni, Sandra Y. Flores, Pierre Meneton, Dorothée Daidié, Olivier Staub
Publikováno v:
Journal of the American Society of Nephrology. 17:1264-1274
The activity of the epithelial sodium (Na(+)) channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN) needs to be tightly regulated to match urinary Na(+) excretion with dietary Na(+) intake. The ubiquitin-protein ligase Nedd4-2, which in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14e5139fc2b15692ba159a7513ba203
https://doi.org/10.1681/asn.2005060659
https://doi.org/10.1681/asn.2005060659
Autor:
Dorothée Daidié, Jean Dudler, Carole Gerbex, Johannes Loffing, Olivier Staub, Elena Kamynina, Sandra Y. Flores, Sting Chabanel, Dominique Loffing-Cueni
Publikováno v:
Journal of the American Society of Nephrology. 16:2279-2287
Aldosterone plays a central role in Na⁺ homeostasis by controlling Na⁺ reabsorption in the aldosterone-sensitive distal nephron involving the epithelial Na⁺ channel (ENaC). Part of the effects of aldosterone is mediated by serum and glucocortic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09605f17f8a930b5e6426c7f0ee6ef48
https://doi.org/10.1681/asn.2004100828
https://doi.org/10.1681/asn.2004100828
Autor:
Marie-Christine Lecomte, Fatemeh Fouladkou, Bruno Vogt, Rasoul Alikhani-Koopaei, Laurence Malbert-Colas, Olivier Staub, Sandra Y. Flores, Brigitte M. Frey, Felix J. Frey, Johannes Loffing
Publikováno v:
American Journal of Physiology-Renal Physiology. 287:F550-F561
The epithelial Na+ channel (ENaC) is regulated by the ubiquitin-protein ligase Nedd4–2 via interaction with ENaC PY-motifs. These PY-motifs are mutated/deleted in Liddle's syndrome, resulting in elevated Na+ reabsorption and hypertension explained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e08cf60deff3848823d495cfe1de849
https://doi.org/10.1152/ajprenal.00353.2003
https://doi.org/10.1152/ajprenal.00353.2003
Autor:
Ahmed Chraibi, Jean-Daniel Horisberger, David A. Pearce, Sandra Y. Flores, Carole Münster, Johannes Loffing, Elena Kamynina, Pamela J. Plant, Caroline Tauxe, Christophe Debonneville, Olivier Staub, Marc A. Thomas, J. Howard Pratt
Publikováno v:
The EMBO Journal. 20:7052-7059
The epithelial Na(+) channel (ENaC) plays an essential role in the regulation of whole body Na(+) balance and blood pressure. The cell surface expression of this channel, a complex of three subunits (alpha, beta and gamma ENaC), has been shown to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcd48b19537a6535e23bbb23c4619c0
https://doi.org/10.1093/emboj/20.24.7052
https://doi.org/10.1093/emboj/20.24.7052
Publikováno v:
Annual review of physiology. 68
▪ Abstract The serum/glucocorticoid-induced kinase Sgk1 plays an important role in the regulation of epithelial ion transport. This kinase is very rapidly regulated at the transcriptional level as well as via posttranslational modifications involvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65dcb8b055f5bfe26426e60277a0431
https://pubmed.ncbi.nlm.nih.gov/16460280
https://pubmed.ncbi.nlm.nih.gov/16460280
Publikováno v:
Pflugers Archiv : European journal of physiology. 446(3)
Ubiquitylation has emerged as an important mechanism for controlling surface expression of membrane proteins. This post-translational modification involves the sequential action of several enzymes including a ubiquitin-activating enzyme E1, a ubiquit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60a21eb5033812aab4720563f1dc143
https://pubmed.ncbi.nlm.nih.gov/12698368
https://pubmed.ncbi.nlm.nih.gov/12698368
Publikováno v:
Molecular reproduction and development. 62(2)
We previously reported that sperm proteasome is responsible for degradation of the ubiquitinated vitelline-coat during fertilization in the ascidian Halocynthia roretzi. Here, we report the roles in fertilization and localization in the sperm cell su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b224e9b5c0fd0e22a49243ecda53d14c
https://pubmed.ncbi.nlm.nih.gov/11984838
https://pubmed.ncbi.nlm.nih.gov/11984838