Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sandra Weissmann"'
Autor:
Armin P. Piehler, Marietta Truger, Jan-Hendrik Kozik, Sandra Weissmann, Martin Schwonzen, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Gregor Hoermann, Claudia Haferlach
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Hemoglobinopathies including thalassemias are among the most frequent genetic disorders worldwide. Primarily, these entities result from germline variants in the globin gene clusters and their cis-acting regulatory elements, and thus the WHO classifi
Externí odkaz:
https://doaj.org/article/41ae9cd75060453ab9bfd4d2a7b5dd66
Autor:
Sabine Jeromin, Torsten Haferlach, Sandra Weissmann, Manja Meggendorfer, Christiane Eder, Niroshan Nadarajah, Tamara Alpermann, Alexander Kohlmann, Wolfgang Kern, Claudia Haferlach, Susanne Schnittger
Publikováno v:
Haematologica, Vol 100, Iss 4 (2015)
Externí odkaz:
https://doaj.org/article/7da4c9c9c672403b9980afb045648b60
Autor:
Constance Baer, Sandra Weissmann, Manja Meggendorfer, Calogero Vetro, Wolfgang Kern, Torsten Haferlach, Sabine Jeromin, Anna Stengel, Claudia Haferlach, Niroshan Nadarajah, Melanie Zenger
Publikováno v:
British journal of haematology. 183(1)
Chronic Lymphocytic Leukaemia (CLL) is a heterogeneous disease with a clinical course dependent on cytogenetic features. However, in 15-20% of cases both chromosome banding and fluorescence in situ hybridisation analyses do not show any kind of abnor
Autor:
Alexander Kohlmann, Wolfgang Kern, Frauke Bellos, Melanie Zenger, Susanne Schnittger, Franziska Kunze, Claudia Haferlach, Torsten Haferlach, Sandra Weissmann, Verena Mühlbacher
Publikováno v:
Genes, Chromosomes and Cancer. 53:524-536
B lymphoblastic leukemia/lymphoma (ALL) are subdivided by the WHO classification into five subgroups defined by specific translocations and two further subgroups defined by the number of chromosomes. The hypodiploid subgroup is heterogeneous and comp
Autor:
Manja Meggendorfer, Torsten Haferlach, Nirsoshan Nadarajah, Sandra Weissmann, Christiane Eder, Susanne Schnittger, Claudia Haferlach, Sabine Jeromin, Alexander Kohlmann, Tamara Alpermann, Wolfgang Kern
Publikováno v:
Haematologica. 100:e125-e127
Refractory anemia with ring sideroblasts and marked thrombocytosis (RARS-T) is a rare entity with characteristics of both myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN).[1][1] Patients have been shown to be frequently JAK2 V61
Autor:
Susanne Schnittger, Sandra Weissmann, Alexander Kohlmann, T Haferlach, Wolfgang Kern, Sabine Jeromin, Vera Grossmann, Tamara Alpermann, K Bayer, Andreas Roller, Claudia Haferlach, Frank Dicker
Publikováno v:
Leukemia. 28:108-117
We analyzed a large cohort of 1160 untreated CLL patients for novel genetic markers (SF3B1, NOTCH1, FBXW7, MYD88, XPO1) in the context of molecular, immunophenotypic and cytogenetic data. NOTCH1 mutations (mut) (12.3%), SF3B1mut (9.0%) and TP53mut (7
Autor:
Marita Staller, Annette Fasan, Christiane Eder, Claudia Haferlach, Melanie Zenger, Torsten Haferlach, Alexander Kohlmann, Wolfgang Kern, Sandra Weissmann, Ulrike Bacher, Susanne Schnittger, Franziska Poetzinger, Andreas Roller, Vera Grossmann
Publikováno v:
Leukemia. 27:1940-1943
Abstract 1394 Background: Acute erythroid leukemia (AEL) is characterized by a predominant erythroid population and is comprising Aims: Molecular and cytogenetic characterization of AEL and identification of genes with prognostic impact. Patients and
Autor:
Christiane Eder, Susanne Schnittger, Alexander Kohlmann, Wolfgang Kern, Andreas Roller, Vera Grossmann, Elisa Stopp, Annette Fasan, Claudia Haferlach, Niroshan Nadarajah, Sandra Weissmann, Torsten Haferlach
Publikováno v:
British Journal of Haematology. 161:649-658
Summary Acute myeloid leukaemia (AML) with CEBPA mutations is listed as a provisional entity in the current World Health Organization classification. A difference in clinical outcome between single- (sm) and double-mutated (dm) cases has been reporte
Autor:
Alexander Kohlmann, Wolfgang Kern, Franziska Poetzinger, Vera Grossmann, Ulrike Bacher, Andreas Roller, Susanne Schnittger, L Boeck, Sandra Weissmann, Niroshan Nadarajah, Torsten Haferlach, Claudia Haferlach
Publikováno v:
Leukemia. 27:1573-1578
Autor:
Sandra Weissmann, Ulrike Bacher, Alexander Kohlmann, Susanne Schnittger, Wolfgang Kern, Tamara Alpermann, Claudia Haferlach, Torsten Haferlach, Sonja Schindela
Publikováno v:
British Journal of Haematology. 156:67-75
TET2 mutations have been identified in 10-25% of patients with myeloid malignancies, but TET2 gene copy number alterations remain to be evaluated. We performed interphase and metaphase fluorescence in situ hybridization (FISH), using newly designed p