Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sandra Viale"'
Autor:
Rossana Ruiz, Marco Galvez-Nino, Katia Roque, Jaime Montes, Maria Nuñez, Luis Raez, Sergio Sánchez-Gambetta, Sandra Jaúregui, Sandra Viale, Edward S. Smith, Joseph A. Pinto, Luis Mas
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundLung cancer in the young is a rare entity of great interest due to the high frequency of targetable mutations. In this study, we explored the genomic landscape of non-small cell lung cancer (NSCLC) in young patients and compared it with gen
Externí odkaz:
https://doaj.org/article/03b78a0649fd43e9a200455e6923a309
Autor:
Matthew J. Birket, Sophie Raibaud, Miriam Lettieri, Antony D. Adamson, Valerie Letang, Pauline Cervello, Nicolas Redon, Gwenaelle Ret, Sandra Viale, Bing Wang, Bruno Biton, Jean-Claude Guillemot, Vincent Mikol, John P. Leonard, Neil A. Hanley, Cecile Orsini, Jean-Michel Itier
Publikováno v:
Stem Cell Reports, Vol 13, Iss 2, Pp 380-393 (2019)
Summary: Here, we have used patient-derived induced pluripotent stem cell (iPSC) and gene-editing technology to study the cardiac-related molecular and functional consequences of mutations in GLA causing the lysosomal storage disorder Fabry disease (
Externí odkaz:
https://doaj.org/article/c2c19783b4b74745a6875cfbc1a18bb7
Autor:
Gwenaelle Ret, Pauline Cervello, Nicolas Redon, Matthew J. Birket, Miriam Lettieri, Valérie Letang, Bing Wang, Jean-Claude Guillemot, Bruno Biton, John P. Leonard, Sandra Viale, Vincent Mikol, Antony Adamson, Cécile Orsini, Jean-Michel Itier, Sophie Raibaud, Neil A. Hanley
Publikováno v:
Stem Cell Reports, Vol 13, Iss 2, Pp 380-393 (2019)
Birket, M J, Raibaud, S, Lettieri, M, Adamson, A D, Letang, V, Cervello, P, Redon, N, Ret, G, Viale, S, Wang, B, Biton, B, Guillemot, J C, Mikol, V, Leonard, J P, Hanley, N A, Orsini, C & Itier, J M 2019, ' A Human Stem Cell Model of Fabry Disease Implicates LIMP-2 Accumulation in Cardiomyocyte Pathology ', Stem Cell Reports, vol. 13, no. 2, pp. 380-393 . https://doi.org/10.1016/j.stemcr.2019.07.004
Stem Cell Reports
Birket, M J, Raibaud, S, Lettieri, M, Adamson, A D, Letang, V, Cervello, P, Redon, N, Ret, G, Viale, S, Wang, B, Biton, B, Guillemot, J C, Mikol, V, Leonard, J P, Hanley, N A, Orsini, C & Itier, J M 2019, ' A Human Stem Cell Model of Fabry Disease Implicates LIMP-2 Accumulation in Cardiomyocyte Pathology ', Stem Cell Reports, vol. 13, no. 2, pp. 380-393 . https://doi.org/10.1016/j.stemcr.2019.07.004
Stem Cell Reports
Summary Here, we have used patient-derived induced pluripotent stem cell (iPSC) and gene-editing technology to study the cardiac-related molecular and functional consequences of mutations in GLA causing the lysosomal storage disorder Fabry disease (F
Autor:
Torsten E. Reichert, Christian Morsczeck, Christoph Klingelhöffer, Tobias Ettl, Sandra Viale-Bouroncle
Publikováno v:
Cellular Signalling. 27:598-605
The directed expression of osteogenic transcription factors via a balanced activation of signaling pathways is an important prerequisite for the development of mineralized tissues. A positive-feedback loop of the BMP2-dependent SMAD signaling pathway
Autor:
Martin Gosau, Torsten E. Reichert, Christian Morsczeck, Tobias Ettl, Sandra Viale-Bouroncle, Matthias G. Hautmann, Oliver Kölbl
Publikováno v:
Oral Oncology. 51:158-163
Summary Objectives Induction of apoptosis is a major mechanism of radiosensitivity in different types of cancer. In contrast, EGFR/PI3K/AKT signalling and recently the presence of so-called cancer stem cells are discussed as reasons for radioresistan
Publikováno v:
Molecular Cell. 55(1):47-58
The ubiquitin-like SUMO system regulates gene expression, but the molecular insights into this process are incomplete. We show that the SUMO-specific isopeptidase SENP3 controls H3K4 methylation by regulating histone-modifying SET1/MLL complexes. SET
Publikováno v:
International Endodontic Journal. 48:185-192
Aim To evaluate whether and how the transcription factor early growth response gene 1 (EGR1) affects the osteogenic differentiation of dental stem cells. Methodology Dental stem cells from apical papilla (SCAPs) and from the dental follicle (DFCs) we
Autor:
Gwenaelle Ret, Anne Caron, Cécile Orsini, Jean-François Deleuze, Dinesh S. Bangari, John P. Leonard, Lindsay Sweet, Sandra Viale, Jean-Michel Itier, Bernard Bénichou, Françoise Le-Gall
Publikováno v:
Journal of Inherited Metabolic Disease. 37:1013-1022
Fabry disease, a rare X-linked α-galactosidase A deficiency, causes progressive lysosomal accumulation of globotriaosylceramide (GL-3) in a variety of cell types. As the disease progresses, renal failure, left ventricular hypertrophy, and strokes ma
Publikováno v:
Calcified Tissue International. 92:412-417
Dental stem cells represent a good treatment option in regenerative dentistry. Regeneration of large bone defects can be achieved by a cell-based therapy consisting of osteogenic progenitor cells, such as dental follicle precursor cells (DFCs), in co
Autor:
Christian Morsczeck, Torsten E. Reichert, Sandra Viale-Bouroncle, Gottfried Schmalz, Oliver Felthaus
Publikováno v:
The International Journal of Oral & Maxillofacial Implants. 28:e478-e486
Dental stem cells are excellent for oral and craniofacial tissue engineering. A profound knowledge about molecular processes in dental stem cells is necessary to create treatment approaches in oral medicine. Transcription factors regulate gene expres