Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sandra Valeria Vassiliades"'
Autor:
Elisa Souza Vaz, Sandra Valeria Vassiliades, Jeanine Giarolla, Michelle Carneiro Polli, Roberto Parise-Filho
Publikováno v:
European Journal of Clinical Pharmacology.
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 23
Abstract: The folate metabolic cycle is an important biochemical process for the maintenance of cellular homeostasis, and is a widely studied pathway of cellular replication control in all organisms. In microorganisms such as M. tuberculosis (Mtb), f
Autor:
Roberto Parise-Filho, Thais Batista Fernandes, Rosania Yang, Glaucio Monteiro Ferreira, Priscila Oliveira de Souza, Vitor Galvão Lopes, Mônica Franco Zannini Junqueira Toledo, Gabriela Gonçalves Roliano, Gabriela Nogueira Debom, Sandra Valeria Vassiliades, Neuza Mariko Aymoto Hassimotto, Mario Hiroyuki Hirata, Elizandra Braganhol
Publikováno v:
Letters in Drug Design & Discovery. 20
Background: Glioblastoma is one of the most aggressive types of tumors, which occurs in the central nervous system, and has a high fatality rate. Among the cellular changes observed in glioblastoma is the overexpression of certain anti-apoptotic prot
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Tuberculosis is a disease with a high level of incidence and mortality. Due to the problems associated with current therapy, it is necessary and urgent to develop new drugs for treatment. Dihydrofolate reductase (DHFR) is a recognized target for the