Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sandra Turconi"'
Autor:
Andrew J. Pope, Sandra Turconi, Stephen Ashman, David L. Earnshaw, Ryan P. Bingham, Murray J. B. Brown, Ulrich Haupts, Kenneth Fantom, Kerry Shea
Publikováno v:
SLAS Discovery. 6:275-290
This paper describes, for the first time, a true ultra-high throughput screen (uHTS) based upon fluorescence anisotropy and performed entirely in 1536-well assay plates. The assay is based upon binding and displacement of a BODIPY-FL-labeled antibiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bcd9bb77ec205ec6cf92ff6fe690f2
https://doi.org/10.1177/108705710100600502
https://doi.org/10.1177/108705710100600502
Publikováno v:
Drug Discovery Today. 6:27-39
Homogeneous fluorescence detection methods are proving key in the establishment of miniaturized ultra-HTS (uHTS). Fluorescence lifetime-based methods seem set to provide an additional dimension to these approaches and are likely to represent a signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f39d4cca36763ea0a74422a91645461
https://doi.org/10.1016/s1359-6446(01)00159-3
https://doi.org/10.1016/s1359-6446(01)00159-3
Autor:
Sandra Turconi, Caretha L. Creasy, Robin V. Ward, Eric Karran, Owen Jenkins, Carol W. Gray, Paul S. Carter, Gary Pettman, John Savopoulos
Publikováno v:
Protein Expression and Purification. 19:227-234
HumHtrA2 or Omi is a recently described member of a novel family of mammalian serine proteases homologous to the Escherichia coli htrA gene product. Although the physiological function of members of this new family is unclear, the current understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a797c61b4b5973833accb925a27310db
https://doi.org/10.1006/prep.2000.1240
https://doi.org/10.1006/prep.2000.1240
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1363:1-5
We have compared the optical spectrum of tyrosine oxidised in aqueous solution by pulsed radiolysis with spectra of redox active tyrosines YZ and YD of photosystem II. This indicates a "tyrosinate" state for these tyrosines and also casts doubt on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673441e30d976964f46702b91d03b60e
https://doi.org/10.1016/s0005-2728(97)00077-7
https://doi.org/10.1016/s0005-2728(97)00077-7
Publikováno v:
Biochemistry. 36:7086-7096
Experiments are described which allow the detection and characterization of new EPR signals in photosystem II (PSII). PSII has been extensively studied with the water oxidising complex (WOC) poised in the S1 and S2 states. Other stages in the cycle o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4121bb02c38cb18cc128c7c085393579
https://doi.org/10.1021/bi962179p
https://doi.org/10.1021/bi962179p
Autor:
Michael C.W. Evans, Yangzhen Ciringh, Colin P. Horwitz, Susan T. Weintraub, Joseph T. Warden, Jonathan H. A. Nugent, Sandra Turconi
Publikováno v:
Le Journal de Physique IV. 7:C2-603
A complex containing four manganese centres is thought to be the catalytic site of photosynthetic water oxidation. The structure and mechanism of action of this complex are largely unknown. Mn-coordination complexes can be used as models for the mang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16fc218753253ef0d59e73f9c2e2064d
https://doi.org/10.1051/jp4/1997111
https://doi.org/10.1051/jp4/1997111
Autor:
Susan T. Weintraub, Yangzhen Ciringh, Colin P. Horwitz, Joseph T. Warden, Michael C.W. Evans, Jonathan H. A. Nugent, Sandra Turconi
Publikováno v:
Journal of the Chemical Society, Dalton Transactions. :4075-4082
An X-ray absorption spectroscopic study was made of seven different manganese co-ordination compounds, six of which are dinuclear and contain the structural bis(µ-oxo) unit. In all the compounds each manganese is ligated by one crown ether Schiff-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeac0279b07cf1d7feef8b521d9e562b
https://doi.org/10.1039/a700044h
https://doi.org/10.1039/a700044h
Autor:
Michael C.W. Evans, Dugald J. MacLachlan, Jonathan H. A. Nugent, Sandra Turconi, Peter J. Bratt
Publikováno v:
Biochemistry. 36:879-885
The association of water with the Mn of the water oxidizing complex was investigated using H2(17)O- and 2H2O-reconstituted lyophilized photosystem II particles. The pulsed electron paramagnetic resonance (EPR) technique of electron spin echo envelope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de90c6a6437d830b1d51ff742d80ed89
https://doi.org/10.1021/bi962010b
https://doi.org/10.1021/bi962010b
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1187:324-334
Two different Triton X-100 isolated photosystem (PS) I particle preparations as well as isolated light-harvesting complex (LHC) I from spinach have been studied by steady state and time-resolved fluorescence with a time resolution of about 5 ps. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce7ab2f3303403ce2236529da342efca
https://doi.org/10.1016/0005-2728(94)90006-x
https://doi.org/10.1016/0005-2728(94)90006-x
Autor:
Michael C.W. Evans, Stuart V. Ruffle, Stephen E. J. Rigby, Peter J. Bratt, Jonathan H. A. Nugent, Sandra Turconi, Dugald J. MacLachlan
Publikováno v:
Biochemical Society Transactions. 22:327-331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13404eda3f4104994470f9a8216cfc74
https://doi.org/10.1042/bst0220327
https://doi.org/10.1042/bst0220327