Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sandra Tong"'
Autor:
Frederick W.K. Tam, James Tumlin, Jonathan Barratt, Brad H. Rovin, Ian S.D. Roberts, Candice Roufosse, H. Terence Cook, Gurjeet Bhangal, Alison L. Brown, Martin Busch, Fayaz Dudhiya, Anne-Marie Duliege, Donald J. Fraser, Daniel P. Gale, Chiu-Ching Huang, Ping-Chin Lai, Meng Lee, Esteban S. Masuda, Stephen P. McAdoo, Alexander R. Rosenkranz, Claudia Sommerer, Gere Sunder-Plassmann, Cheuk-Chun Szeto, Sydney C.W. Tang, Don E. Williamson, Lisa Willcocks, Volker Vielhauer, Min Jeong Kim, Leslie Todd, Hany Zayed, Sandra Tong-Starksen, Richard Lafayette
Publikováno v:
Kidney International Reports, Vol 8, Iss 12, Pp 2546-2556 (2023)
Introduction: We reported increased spleen tyrosine kinase (SYK) expression in kidney biopsies of patients with IgA nephropathy (IgAN) and that inhibition of SYK reduces inflammatory cytokines production from IgA stimulated mesangial cells. Methods:
Externí odkaz:
https://doaj.org/article/66982ca5bf66483cb14ee295eaf07526
Autor:
Caroline R. Stanclift, Selina S. Dwight, Kevin Lee, Quirine L. Eijkenboom, Matt Wilsey, Kristen Wilsey, Erica Sanford Kobayashi, Sandra Tong, Matthew N. Bainbridge
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-8 (2022)
Abstract Purpose NGLY1 Deficiency is an ultra-rare, multisystemic disease caused by biallelic pathogenic NGLY1 variants. The aims of this study were to (1) characterize the variants and clinical features of the largest cohort of NGLY1 Deficiency pati
Externí odkaz:
https://doaj.org/article/22e982c08c3c4e699db286ae244a6d50
Autor:
Heather L. Gelhorn, Xin Ye, Rebecca M. Speck, Sandra Tong, John H. Healey, Susan V. Bukata, Richard D. Lackman, Lindsey Murray, Grant Maclaine, William R. Lenderking, Henry H. Hsu, Paul S. Lin, William D. Tap
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 3, Iss 1, Pp 1-10 (2019)
Abstract Background Tenosynovial giant cell tumor (TGCT), a rare, locally aggressive neoplasm of the synovium of joints and tendon sheaths, is associated with joint destruction, pain and swelling. Impacts on physical function (PF) vary depending on t
Externí odkaz:
https://doaj.org/article/3b9d9a0dde9d4cbaa55b1d964b7357b1
Autor:
Sandra Tong, Pamela Ventola, Christina H. Frater, Jenna Klotz, Jennifer M. Phillips, Srikanth Muppidi, Selina S. Dwight, William F. Mueller, Brendan J. Beahm, Matt Wilsey, Kevin J. Lee
N-glycanase 1 (NGLY1) Deficiency is a debilitating, ultra-rare autosomal recessive disorder caused by loss of function of NGLY1, a cytosolic enzyme that deglycosylates other proteins. It is characterized by severe global developmental delay and/or in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99b5aaae221e3690d926f49815c1d09f
https://doi.org/10.1101/2023.05.10.23289581
https://doi.org/10.1101/2023.05.10.23289581
Autor:
Sandra Tong-Starksen, Paul S. Lin, Brian L. West, Paul Severson, Xin Ye, Heather L. Gelhorn, Charles Peterfy, Henry H. Hsu, Eric Sherman, Fadi Braiteh, Andrew J. Wagner, Gregory M. Cote, Igor Puzanov, Zev A. Wainberg, Vicki L. Keedy, Geoffrey I. Shapiro, Allen Lee Cohn, Bartosz Chmielowski, John H. Healey, Chao Zhang, Mike Sterba, Stephen Patrick Anthony, Arun S. Singh, William D. Tap
Purpose:To assess the response to pexidartinib treatment in six cohorts of adult patients with advanced, incurable solid tumors associated with colony-stimulating factor 1 receptor (CSF1R) and/or KIT proto-oncogene receptor tyrosine kinase activity.P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c23a45df4ab5ad4ce47e4769969c45
https://doi.org/10.1158/1078-0432.c.6530892
https://doi.org/10.1158/1078-0432.c.6530892
Autor:
Sandra Tong-Starksen, Paul S. Lin, Brian L. West, Paul Severson, Xin Ye, Heather L. Gelhorn, Charles Peterfy, Henry H. Hsu, Eric Sherman, Fadi Braiteh, Andrew J. Wagner, Gregory M. Cote, Igor Puzanov, Zev A. Wainberg, Vicki L. Keedy, Geoffrey I. Shapiro, Allen Lee Cohn, Bartosz Chmielowski, John H. Healey, Chao Zhang, Mike Sterba, Stephen Patrick Anthony, Arun S. Singh, William D. Tap
Supplementary Data from Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e149a7afcdc68bbe63a27f167cc400b
https://doi.org/10.1158/1078-0432.22482318.v1
https://doi.org/10.1158/1078-0432.22482318.v1
Autor:
James B. Bussel, Quentin A. Hill, Michelle Sholzberg, Nichola Cooper, Michael D. Tarantino, Sandra Tong, Leslie Todd, Ralph V. Boccia, Michael Boxer, Waleed Ghanima
Publikováno v:
British Journal of Haematology
Fostamatinib demonstrated efficacy in phase 3 trials of adults with immune thrombocytopenia (ITP). Post hoc analysis compared patients who received fostamatinib as second‐line therapy (after steroids ± immunoglobulins) versus third‐or‐later‐
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9386d56a8017c6d25bb456b3db7392d4
http://europepmc.org/articles/PMC7540289
http://europepmc.org/articles/PMC7540289
Autor:
David J. Kuter, Kerry A. Rogers, Michael A. Boxer, Michael Choi, Richy Agajanian, Donald M. Arnold, Catherine M. Broome, Joshua J. Field, Irina Murakhovskaya, Robert Numerof, Sandra Tong
Publikováno v:
American journal of hematology. 97(6)
Patients with relapsed warm antibody autoimmune hemolytic anemia (wAIHA) have limited treatment options. Fostamatinib is a potent, orally administered spleen tyrosine kinase inhibitor approved in the United States and Europe for the treatment of adul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68e718b972539c001b379f6b5ea600e
https://pubmed.ncbi.nlm.nih.gov/35179251
https://pubmed.ncbi.nlm.nih.gov/35179251
Autor:
Paul S. Lin, Charles Peterfy, Andrew J. Wagner, John H. Healey, Mike Sterba, Gregory M. Cote, Paul Severson, Heather L. Gelhorn, Eric J. Sherman, Chao Zhang, Henry H. Hsu, Geoffrey I. Shapiro, Arun S. Singh, Sandra Tong-Starksen, Stephen P. Anthony, Bartosz Chmielowski, Fadi Braiteh, Allen Lee Cohn, Igor Puzanov, William D. Tap, Brian L. West, Vicki L. Keedy, Xin Ye, Zev A. Wainberg
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 28, iss 2
Purpose: To assess the response to pexidartinib treatment in six cohorts of adult patients with advanced, incurable solid tumors associated with colony-stimulating factor 1 receptor (CSF1R) and/or KIT proto-oncogene receptor tyrosine kinase activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09343ab321622061b5ecb1934239019
https://pubmed.ncbi.nlm.nih.gov/34716196
https://pubmed.ncbi.nlm.nih.gov/34716196
Publikováno v:
Blood. 136:1-3
Background. Warm antibody autoimmune hemolytic anemia (wAIHA) is a rare disorder that can be potentially serious. In wAIHA, autoantibodies react with protein antigens on red blood cells (RBCs) at body temperature, leading to RBC phagocytosis and dest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5269ed58c83e7c339bde049acc000259
https://doi.org/10.1182/blood-2020-140469
https://doi.org/10.1182/blood-2020-140469