Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Sandra Swist"'
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Akademický článek
Maintenance of sarcomeric integrity in adult muscle cells crucially depends on Z-disc anchored titin
Autor: Sandra Swist, Andreas Unger, Yong Li, Anja Vöge, Marion von Frieling-Salewsky, Åsa Skärlén, Nicola Cacciani, Thomas Braun, Lars Larsson, Wolfgang A. Linke
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Titin is considered an integrator of muscle cell proteins but direct evidence is limited. Here, titin is inactivated in adult mouse muscles, which causes sarcomere disassembly, protein mis-expression and force impairment, recapitulating key alteratio
Externí odkaz: https://doaj.org/article/302edbcae576463d8910dcb3be630c60
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2
Inhibitory SMAD6 interferes with BMP dependent generation of muscle progenitor cells and perturbs proximodistal pattern of murine limb muscles
Autor: Hasan Asfour, Estelle Hirsinger, Raquel Rouco, Faouzi Zarrouki, Shinichiro Hayashi, Sandra Swist, Thomas Braun, Ketan Patel, Frédéric Relaix, Guillaume Andrey, Sigmar Stricker, Delphine Duprez, Amalia Stantzou, Helge Amthor
Publikováno v: Development.
The mechanism of pattern formation during limb muscle development remains poorly understood. The canonical view holds that naïve limb muscle progenitor cells (MPCs) invade a pre-established pattern of muscle connective tissue, thereby forming indivi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::894e17ad845af17e7e1e94da99dde5c6
https://doi.org/10.1242/dev.201504
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3
BMP9 and BMP10 Act Directly on Vascular Smooth Muscle Cells for Generation and Maintenance of the Contractile State
Autor: Fan Wu, Thomas Braun, Matthew T. Wheeler, André Schneider, Simone Kraut, Norbert Weissmann, Sandra Swist, Shengpeng Wang, Thomas Böttger, Thomas Kubin, Lei Wang, Megan S. Rice
Publikováno v: Circulation. 143:1394-1410
Background: Vascular smooth muscle cells (VSMCs) show a remarkable phenotypic plasticity, allowing acquisition of contractile or synthetic states, but critical information is missing about the physiologic signals, promoting formation, and maintenance
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5eed877a9479c961f592ac795207ec
https://doi.org/10.1161/circulationaha.120.047375
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5
Maintenance of sarcomeric integrity in adult muscle cells crucially depends on Z-disc anchored titin
Autor: Wolfgang A. Linke, Åsa Skärlén, Anja Vöge, Andreas Unger, Thomas Braun, Sandra Swist, Yong Li, Lars Larsson, Marion von Frieling-Salewsky, Nicola Cacciani
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
The giant protein titin is thought to be required for sarcomeric integrity in mature myocytes, but direct evidence for this hypothesis is limited. Here, we describe a mouse model in which Z-disc-anchored TTN is depleted in adult skeletal muscles. Ina
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29b0ba85ada047c9840cc4565947500
https://pubmed.ncbi.nlm.nih.gov/32900999
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6
BMP signaling regulates satellite cell-dependent postnatal muscle growth
Autor: Thomas Braun, Etienne Mouisel, Céline Colnot, Amalia Stantzou, Faouzi Zarrouki, Sandra Swist, Fabien Le Grand, Cyriaque Beley, Frédéric Relaix, Ioanna Polydorou, Helge Amthor, Luis Garcia, Sonia Alonso-Martin, Carmen Birchmeier, Markus Schuelke, Anaïs Julien, Elija Schirwis
Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), 2017, 144 (15), pp.2737-2747. ⟨10.1242/dev.144089⟩
Development (Cambridge, England), Company of Biologists, 2017, 144 (15), pp.2737-2747. ⟨10.1242/dev.144089⟩
Postnatal growth of skeletal muscle largely depends on the expansion and differentiation of resident stem cells, the so-called satellite cells. Here, we demonstrate that postnatal satellite cells express components of the bone morphogenetic protein (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d820807ce4afde30c51d7f95875187
https://hal.science/hal-02407976
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7
HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
Autor: John T, Hinson, Anant, Chopra, Navid, Nafissi, William J, Polacheck, Craig C, Benson, Sandra, Swist, Joshua, Gorham, Luhan, Yang, Sebastian, Schafer, Calvin C, Sheng, Alireza, Haghighi, Jason, Homsy, Norbert, Hubner, George, Church, Stuart A, Cook, Wolfgang A, Linke, Christopher S, Chen, J G, Seidman, Christine E, Seidman
Publikováno v: Science (New York, N.Y.). 349(6251)
Human mutations that truncate the massive sarcomere protein titin [TTN-truncating variants (TTNtvs)] are the most common genetic cause for dilated cardiomyopathy (DCM), a major cause of heart failure and premature death. Here we show that cardiac mic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b73618d71fcfdd6c4f8de991e1d2c0c2
https://pubmed.ncbi.nlm.nih.gov/26635381
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