Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Sandra Spurr-Michaud"'
Autor:
Balaraj B. Menon, Xiaohong Zhou, Sandra Spurr-Michaud, Jaya Rajaiya, James Chodosh, Ilene K. Gipson
Publikováno v:
mSphere, Vol 1, Iss 1 (2016)
ABSTRACT Human adenoviruses (HAdV), species D in particular (HAdV-D), are frequently associated with epidemic keratoconjunctivitis (EKC). Although the infection originates at the ocular surface epithelium, the mechanisms by which HAdV-Ds bypass the m
Externí odkaz:
https://doaj.org/article/d3fd5570a07a4b0eae47eb608bbe164d
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100393 (2014)
Membrane-anchored mucins are present in the apical surface glycocalyx of mucosal epithelial cells, each mucosal epithelium having at least two of the mucins. The mucins have been ascribed barrier functions, but direct comparisons of their functions w
Externí odkaz:
https://doaj.org/article/abe8891505df4103b8263c97bffaec8c
Autor:
Bharathi Govindarajan, Balaraj B Menon, Sandra Spurr-Michaud, Komal Rastogi, Michael S Gilmore, Pablo Argüeso, Ilene K Gipson
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32418 (2012)
The majority of bacterial infections occur across wet-surfaced mucosal epithelia, including those that cover the eye, respiratory tract, gastrointestinal tract and genitourinary tract. The apical surface of all these mucosal epithelia is covered by a
Externí odkaz:
https://doaj.org/article/f8c9e9a4996742299d877c501f8a2664
Autor:
Sandra Spurr-Michaud, Claes H. Dohlman, Marie-Claude Robert, James Chodosh, Samer N. Arafat, Ilene K. Gipson
Publikováno v:
Cornea. 35:1008-1014
Purpose To investigate the tear levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO), and tissue inhibitor of metalloproteinase-1 in eyes after Boston keratoprosthesis type I (B-KPro) implantation and to correlate these markers with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ab6a066c30fe5997ad28e23d72ad78
https://doi.org/10.1097/ico.0000000000000893
https://doi.org/10.1097/ico.0000000000000893
Publikováno v:
Experimental Eye Research. 145:230-234
MUC16 is an extraordinarily large 22,152 amino acid membrane spanning mucin that has been shown to be present in the glycocalyx of the apical cells of the human cornea and conjunctiva where it interfaces with the tear film. The ectodomain of the mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1595343442b522743aef7d869bebf97
https://doi.org/10.1016/j.exer.2015.12.009
https://doi.org/10.1016/j.exer.2015.12.009
Autor:
Balaraj B. Menon, Christina Kaiser-Marko, Ilene K. Gipson, Ann S. Tisdale, Sandra Spurr-Michaud
Publikováno v:
Mucosal immunology
Membrane-associated mucins (MAMs) expressed on the ocular surface epithelium form a dense glycocalyx that is hypothesized to protect the cornea and conjunctiva from external insult. In this study, the hypothesis that the MAMs MUC1 and MUC16, expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef90f2a8b1750bf88a2b444e0b358761
http://europepmc.org/articles/PMC4495011
http://europepmc.org/articles/PMC4495011
Autor:
James Chodosh, Ana M. Suelves, Sandra Spurr-Michaud, C. Stephen Foster, Claes H. Dohlman, Samer N. Arafat, Ilene K. Gipson
Publikováno v:
Ophthalmology. 121:79-87
Objective To investigate the levels of matrix metalloproteinases (MMPs), myeloperoxidase (MPO), and tissue inhibitor of metalloproteinase-1 (TIMP-1) in tears of patients with Stevens-Johnson syndrome (SJS) and ocular cicatricial pemphigoid (OCP). Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dfd56b18066681a07c7b02071df08b6
https://doi.org/10.1016/j.ophtha.2013.06.049
https://doi.org/10.1016/j.ophtha.2013.06.049
Autor:
Samer N. Arafat, Claes H. Dohlman, Sandra Spurr-Michaud, Reza Dana, Tulio B. Abud, Francisco Amparo, Ilene K. Gipson, Marie-Claude Robert
Publikováno v:
American journal of ophthalmology. 176
To investigate the levels of neutrophil elastase (NE), matrix metalloproteinases (MMPs), and myeloperoxidase (MPO) in tear washes of patients with ocular graft-vs-host disease (oGVHD).Case-control study.Based on established criteria, oGVHD patients (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da6366d9cb2a704d17daef7d211a3a5
https://pubmed.ncbi.nlm.nih.gov/28073648
https://pubmed.ncbi.nlm.nih.gov/28073648
Autor:
Sandra Spurr-Michaud, Balaraj B. Menon, Ilene K. Gipson, James Chodosh, Jaya Rajaiya, Xiaohong Zhou
Publikováno v:
mSphere
mSphere, Vol 1, Iss 1 (2016)
mSphere, Vol 1, Iss 1 (2016)
Human adenoviruses (HAdVs) are double-stranded DNA viruses that cause infections across all mucosal tissues in the body. At the ocular surface, HAdVs cause keratoconjunctivitis (E. Ford, K. E. Nelson, and D. Warren, Epidemiol Rev 9:244–261, 1987, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389db67dc0ec360a71c8aede936251a4
https://doi.org/10.1128/msphere.00112-15
https://doi.org/10.1128/msphere.00112-15
Publikováno v:
Cornea. 28:808-811
To determine in vitro whether titanium is superior in corneal cell compatibility to standard polymethyl-methacrylate (PMMA) for the Boston Keratoprosthesis (KPro).Human corneal-limbal epithelial (HCLE) cells were cultured 24, 48, 72, 96, 120, 144, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0582c9cc773b8a5b8259cc287c2347cd
https://doi.org/10.1097/ico.0b013e31819670ac
https://doi.org/10.1097/ico.0b013e31819670ac