Výsledky vyhledávání - "Sandra Sernbo"

Akademický článek

Nuclear T-STAR protein expression correlates with HER2 status, hormone receptor negativity and prolonged recurrence free survival in primary breast cancer and decreased cancer cell growth in vitro.

Autor: Sandra Sernbo, Carl A K Borrebaeck, Mathias Uhlén, Karin Jirström, Sara Ek

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e70596 (2013)

T-STAR (testis-signal transduction and activation of RNA) is an RNA binding protein, containing an SH3-binding domain and thus potentially playing a role in integration of cell signaling and RNA metabolism. The specific function of T-STAR is unknown

Externí odkaz: https://doaj.org/article/d2ffc93e2d20467194e451a4e85743d1

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Akademický článek

Strong lymphoid nuclear expression of SOX11 transcription factor defines lymphoblastic neoplasms, mantle cell lymphoma and Burkitt’s lymphoma

Autor: Michael Dictor, Sara Ek, Maria Sundberg, Janina Warenholt, Czabafy György, Sandra Sernbo, Elin Gustavsson, Waleed Abu-Alsoud, Torkel Wadström, Carl Borrebaeck

Publikováno v: Haematologica, Vol 94, Iss 11 (2009)

Background We surveyed lymphomas to determine the range of expression of the mantle cell lymphoma-associated SOX11 transcription factor and its relation to cyclin D1.Design and Methods On hundred and seventy-two specimens were immunostained for the S

Externí odkaz: https://doaj.org/article/6e9b9b88d7ae4dd695c8a2dddffc8850

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TGF-β/SMAD Pathway Is Modulated by miR-26b-5p: Another Piece in the Puzzle of Chronic Lymphocytic Leukemia Progression

Autor: Maria Elena Marquez, Sandra Sernbo, Eugenia Payque, Rita Uria, Juan Pablo Tosar, Juliana Querol, Catalina Berca, Angimar Uriepero, Daniel Prieto, Diego Alvarez-Saravia, Carolina Oliver, Victoria Irigoin, Gimena Dos Santos, Cecilia Guillermo, Ana Inés Landoni, Marcelo Navarrete, Florencia Palacios, Pablo Oppezzo

Publikováno v: Cancers; Volume 14; Issue 7; Pages: 1676
COLIBRI
Universidad de la República
instacron:Universidad de la República

Material complementario: https://www.mdpi.com/article/10.3390/cancers14071676/s1 Clinical and molecular heterogeneity are hallmarks of chronic lymphocytic leukemia (CLL), a neoplasm characterized by accumulation of mature and clonal long-lived CD5 +

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86444b5c4ec25cc3ac379ee049d7071

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S100-A9 protein in exosomes from chronic lymphocytic leukemia cells promotes NF-κB activity during disease progression

Autor: Daniel Prieto, Rosario Durán, Sandra Sernbo, Estefanía Sicco, Cecilia Abreu, Carolina Oliver, Pablo Oppezzo, Noé Seija, Raul Gabus, Ana Inés Landoni, Natalia Sotelo, Magdalena Gil, Guillermo Dighiero, Victoria Irigoin

Publikováno v: COLIBRI
Universidad de la República
instacron:Universidad de la República

Chronic lymphocytic leukemia (CLL) is an incurable disease characterized by accumulation of clonal B lymphocytes, resulting from a complex balance between cell proliferation and apoptotic death. Continuous crosstalk between cancer cells and local/dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8763fd928b7297c0976bb9f85a7c4bd
https://pubmed.ncbi.nlm.nih.gov/28596424

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SOX11 and TP53 add prognostic information to MIPI in a homogenously treated cohort of mantle cell lymphoma--a Nordic Lymphoma Group study

Autor: Sandra Sernbo, Lena Nordström, Christian H. Geisler, Riikka Räty, Marja Liisa Karjalainen, Patrik Edén, Sara Ek, Kirsten Grønbæk, Mats Ehinger, Christer Sundström, Anna Laurell, Mats Jerkeman, Jan Delabie, Arne Kolstad, Elisabeth Ralfkiaer

Publikováno v: British Journal of Haematology

Mantle cell lymphoma (MCL) is an aggressive B cell lymphoma, where survival has been remarkably improved by use of protocols including high dose cytarabine, rituximab and autologous stem cell transplantation, such as the Nordic MCL2/3 protocols. In 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b05f87ef1735dbfe514f70d1e3526f
https://pubmed.ncbi.nlm.nih.gov/24684350

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The tumour suppressor SOX11 is associated with improved survival among high grade epithelial ovarian cancers and is regulated by reversible promoter methylation

Autor: Sandra Sernbo, Frida Rydnert, William M. Gallagher, Donal J. Brennan, Karin Jirström, Carl A.K. Borrebaeck, Elin Gustavsson, Sara Ek, Elton Rexhepaj

Publikováno v: BMC Cancer
BMC Cancer, Vol 11, Iss 1, p 405 (2011)
BMC Cancer; 11 (2011)

Background The neural transcription factor SOX11 has been described as a prognostic marker in epithelial ovarian cancers (EOC), however its role in individual histological subtypes and tumour grade requires further clarification. Furthermore, methyla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76aad81fc7e34ae62b00e91a6960389
https://pubmed.ncbi.nlm.nih.gov/21943380

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SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies

Autor: Carl A.K. Borrebaeck, Sara Ek, Michael Dictor, Sandra Sernbo, Elin Gustavsson, Elin Andersson, Mats Jerkeman, Donal J. Brennan

Publikováno v: Molecular Cancer, Vol 9, Iss 1, p 187 (2010)
Molecular Cancer

Background The transcription factor SOX11 plays an important role in embryonic development of the central nervous system (CNS) and is expressed in the adult immature neuron but is normally not expressed in any other adult tissue. It has recently been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2f420353de72a9c7e0839aa8d58a98
https://doi.org/10.1186/1476-4598-9-187

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Strong lymphoid nuclear expression of SOX11 transcription factor defines lymphoblastic neoplasms, mantle cell lymphoma and Burkitt's lymphoma

Autor: Waleed Abu-al-soud, Torkel Wadström, Michael Dictor, Sandra Sernbo, Sara Ek, Janina Warenholt, Carl A.K. Borrebaeck, Elin Gustavsson, Maria Sundberg, Czabafy György

Publikováno v: Haematologica; 94(11), pp 1563-1568 (2009)

BACKGROUND: We surveyed lymphomas to determine the range of expression of the mantle cell lymphoma-associated SOX11 transcription factor and its relation to cyclin D1. DESIGN AND METHODS: On hundred and seventy-two specimens were immunostained for th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5d96e1867c1a815cdba1b5fec28ea3
http://lup.lub.lu.se/record/1512354/file/1516306.pdf

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Increased Expression Levels Of SOX11 Correlates To Overall Survival and Adds Prognostic Value To The MIPI and MIPI-B Index In a Homogenously Treated Cohort

Autor: Sandra Sernbo, Kirsten Groenbaek, R. Raty, Lena Nordström, Arne Kolstad, Christer Sundström, Elisabeth Ralfkiaer, Venera Kuci, Jan Delabie, Anna Laurell, Christian H. Geisler, Mats Ehinger, Marja-Liisa Karjalainen, Sara Ek, Mats Jerkeman

Publikováno v: Blood. 122:4272-4272

Introduction Mantle cell lymphoma (MCL) is an aggressive B cell lymphoma, previously correlated to a short survival of 3-5 years. Modern clinical protocols, combining immunochemotherapy, high-dose therapy and autologous stem cell transplantation (ASC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a35bbbf4b6735fb4038da1451c05a822
https://doi.org/10.1182/blood.v122.21.4272.4272

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Nuclear T-STAR Protein Expression Correlates with HER2 Status, Hormone Receptor Negativity and Prolonged Recurrence Free Survival in Primary Breast Cancer and Decreased Cancer Cell Growth In Vitro

Autor: Sara Ek, Sandra Sernbo, Karin Jirström, Mathias Uhlén, Carl A.K. Borrebaeck

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e70596 (2013)
PLoS ONE; 8(7), no e70596 (2013)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71be9510ff69807bfd73284f07d2fdc9
https://doi.org/10.1371/journal.pone.0070596

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