Výsledky vyhledávání - "Sandra Sczerba Burkett"

Akademický článek

Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion.

Autor: Rebecca Sorber, Yaroslav Teper, Abisola Abisoye-Ogunniyan, Joshua J Waterfall, Sean Davis, J Keith Killian, Marbin Pineda, Satyajit Ray, Matt R McCord, Holger Pflicke, Sandra Sczerba Burkett, Paul S Meltzer, Udo Rudloff

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0149833 (2016)

The genetic profile of human pancreatic cancers harbors considerable heterogeneity, which suggests a possible explanation for the pronounced inefficacy of single therapies in this disease. This observation has led to a belief that custom therapies ba

Externí odkaz: https://doaj.org/article/cec4af1412024e44b4e5f4472f9028f1

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Distinct roles of treatment schemes and BRCA2 on the restoration of homologous recombination DNA repair and PARP inhibitor resistance in ovarian cancer

Autor: Tzu-Ting Huang, Sandra Sczerba Burkett, Mayank Tandon, Tomomi M. Yamamoto, Nitasha Gupta, Benjamin G. Bitler, Jung-Min Lee, Jayakumar R. Nair

Publikováno v: Oncogene

Poly (ADP-ribose) polymerase inhibitors (PARPis) represent a major advance in ovarian cancer, now as a treatment and as a maintenance therapy in the upfront and recurrent settings. However, patients often develop resistance to PARPis, underlining the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74fbfdf19eb66d1ccc175447590707d
https://europepmc.org/articles/PMC9669252/

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