Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sandra Sanchez‐Gregorio"'
Autor:
Ignacio Melero, Maria C Ochoa, Carmen Molina, Sandra Sanchez‐Gregorio, Saray Garasa, Carlos Luri‐Rey, Sandra Hervas‐Stubbs, Noelia Casares, Edurne Elizalde, Gabriel Gomis, Assunta Cirella, Pedro Berraondo, Alvaro Teijeira, Maite Alvarez
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-16 (2023)
Abstract NK‐cell reactivity against cancer is conceivably suppressed in the tumor microenvironment by the interaction of the inhibitory receptor NKG2A with the non‐classical MHC‐I molecules HLA‐E in humans or Qa‐1b in mice. We found that in
Externí odkaz:
https://doaj.org/article/dad7d8e3e32044ab82bb7ccfc15b4a39
Autor:
Itziar Otano, Arantza Azpilikueta, Javier Glez-Vaz, Maite Alvarez, José Medina-Echeverz, Ivan Cortés-Domínguez, Carlos Ortiz-de-Solorzano, Peter Ellmark, Sara Fritzell, Gabriela Hernandez-Hoyos, Michelle Hase Nelson, María Carmen Ochoa, Elixabet Bolaños, Doina Cuculescu, Patricia Jaúregui, Sandra Sanchez-Gregorio, Iñaki Etxeberria, María E. Rodriguez-Ruiz, Miguel F. Sanmamed, Álvaro Teijeira, Pedro Berraondo, Ignacio Melero
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Costimulation has been shown to be required for optimal activation of T cells and it could be delivered either in trans with respect to the source of CD3-TCR ligation or in cis on the same cell. Here the authors show that CD137 costimulation is more
Externí odkaz:
https://doaj.org/article/7b64d9dd29ea4afa8a31f1d7627fa9a5
Autor:
Maria Ochoa, Sandra Sanchez-Gregorio, Alvaro Teijeira, Saray Garasa, Carlos De Andrea, Maria Villalba, Inaki Etxeberria, Ignacio Melero
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a5ff4265dc12f7dad9eba747bd9e828
https://doi.org/10.1136/jitc-2022-sitc2022.0844
https://doi.org/10.1136/jitc-2022-sitc2022.0844
Autor:
Maria Carmen Ochoa, Sandra Sanchez-Gregorio, Carlos E. de Andrea, Saray Garasa, Maite Alvarez, Irene Olivera, Javier Glez-Vaz, Carlos Luri-Rey, Iñaki Etxeberria, Assunta Cirella, Arantza Azpilikueta, Pedro Berraondo, Josepmaria Argemi, Bruno Sangro, Alvaro Teijeira, Ignacio Melero
Publikováno v:
Cell Reports Medicine. 4:101009
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adf7ae1bd9dd8c1d352cd9f88fde994b
https://doi.org/10.1016/j.xcrm.2023.101009
https://doi.org/10.1016/j.xcrm.2023.101009
Autor:
Iñaki Eguren-Santamaría, Inmaculada Rodríguez, Claudia Herrero-Martin, Eva Fernández de Piérola, Arantza Azpilikueta, Sandra Sánchez-Gregorio, Elixabet Bolaños, Gabriel Gomis, Paula Molero-Glez, Enrique Chacón, José Ángel Mínguez, Santiago Chiva, Fernando Diez-Caballero, Carlos de Andrea, Álvaro Teijeira, Miguel F. Sanmamed, Ignacio Melero
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Biomarkers for cancer immunotherapy are an unmet medical need. The group of Daniela Thommen at the NKI recently reported on novel methodologies based on short-term cultures of patient-derived tumor fragments whose cytokine concentrations in the super
Externí odkaz:
https://doaj.org/article/09779cffd119438d95ea60cb833a5d60
Autor:
Itziar, Otano, Arantza, Azpilikueta, Javier, Glez-Vaz, Maite, Alvarez, José, Medina-Echeverz, Ivan, Cortés-Domínguez, Carlos, Ortiz-de-Solorzano, Peter, Ellmark, Sara, Fritzell, Gabriela, Hernandez-Hoyos, Michelle Hase, Nelson, María Carmen, Ochoa, Elixabet, Bolaños, Doina, Cuculescu, Patricia, Jaúregui, Sandra, Sanchez-Gregorio, Iñaki, Etxeberria, María E, Rodriguez-Ruiz, Miguel F, Sanmamed, Álvaro, Teijeira, Pedro, Berraondo, Ignacio, Melero
Publikováno v:
Nature Communications
CD137 (4-1BB; TNFSR9) is an activation-induced surface receptor that through costimulation effects provide antigen-primed T cells with augmented survival, proliferation and effector functions as well as metabolic advantages. These immunobiological me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::176b9270480aabeabd54a27fe67fa1aa
https://pubmed.ncbi.nlm.nih.gov/34911975
https://pubmed.ncbi.nlm.nih.gov/34911975
Autor:
Assunta Cirella, Elixabet Bolaños, Carlos Luri-Rey, Claudia Augusta Di Trani, Irene Olivera, Gabriel Gomis, Javier Glez-Vaz, Beatrice Pinci, Saray Garasa, Sandra Sánchez-Gregorio, Arantza Azpilikueta, Iñaki Eguren-Santamaria, Karmele Valencia, Belén Palencia, Maite Alvarez, Maria C. Ochoa, Álvaro Teijeira, Pedro Berraondo, Ignacio Melero
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 668-682 (2023)
Intratumoral immunotherapy strategies for cancer based on interleukin-12 (IL-12)-encoding cDNA and mRNA are under clinical development in combination with anti-PD-(L)1 monoclonal antibodies. To make the most of these approaches, we have constructed c
Externí odkaz:
https://doaj.org/article/0cbeb48e82c4432eb1d5f41226df6231