Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sandra S. K. Borders"'
Autor:
Justin C. Smith, Samuel Dean Larsen, Leland Otto Weigel, Jeffrey A. Ward, Ryan J. Linder, Susan M. Reutzel-Edens, Perry Clark Heath, Stanley P. Kolis, Marvin M. Hansen, Marcella T. Clayton, Sandra S. K. Borders, Shella Lenyonga Tameze
Publikováno v:
Organic Process Research & Development. 13:198-208
An efficient and scalable synthesis of the clinical candidate 1 is described. The first-generation synthesis built the enantioenriched nitro-aminoindanol core from 6-nitroindanone using a five-step literature route. The second-generation route used a
Autor:
Moher Eric D, John Allan Rieck, Richard D. Miller, Tracy K. Ditsworth, David A. Hay, Sandra S. K. Borders, Mindy B. Forst, Richard C. Hoying, and Duane A. Pierson, Joseph A. Turpin, Varie David Lee, Ryan J. Linder, Jason S. Cronin, David D. Anderson, and Jacob R. Remacle, Molly D. Brady, Hoard David W, Paul N. Dodson, Christopher A. Beck
Publikováno v:
Organic Process Research & Development. 11:546-559
A pilot-plant scale desymmetrization of the cyclic meso-epoxide 4b, using a chiral lithium amide prepared from symmetrical diamine 17, was designed and implemented to provide allylic alcohol 3b in high yield and greater than 99% ee. This chiral alcoh
Autor:
Marvin M. Hansen, Sandra S. K. Borders, Marcella T. Clayton, Perry C. Heath, Stanley P. Kolis, Samuel D. Larsen, Ryan J. Linder, Susan M. Reutzel-Edens, Justin C. Smith, Shella L. Tameze, Jeffrey A. Ward, Leland O. Weigel
Publikováno v:
Organic Process Research & Development; Mar2009, Vol. 13 Issue 2, p198-208, 11p