Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sandra S. Hammer"'
Autor:
Nicole El-Darzi, Natalia Mast, Sandra S. Hammer, Tim F. Dorweiler, Julia V. Busik, Irina A. Pikuleva
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 2, Pp 100323- (2023)
CYP46A1 is a CNS-specific enzyme, which eliminates cholesterol from the brain and retina by metabolism to 24-hydroxycholesterol, thus contributing to cholesterol homeostasis in both organs. 2-Hydroxypropyl-β-cyclodextrin (HPCD), a Food and Drug Admi
Externí odkaz:
https://doaj.org/article/416b987dee114e0eaef22c32059e6f1f
Autor:
Sandra S. Hammer, Eleni Beli, Nermin Kady, Qi Wang, Kiana Wood, Todd A. Lydic, Goldis Malek, Daniel R. Saban, Xiaoxin X. Wang, Sugata Hazra, Moshe Levi, Julia V. Busik, Maria B. Grant
Publikováno v:
EBioMedicine, Vol 22, Iss C, Pp 181-190 (2017)
Diabetic retinopathy (DR) is a complication secondary to diabetes and is the number one cause of blindness among working age individuals worldwide. Despite recent therapeutic breakthroughs using pharmacotherapy, a cure for DR has yet to be realized.
Externí odkaz:
https://doaj.org/article/f73117b5dd974be191c934e1c359ea8d
Autor:
Nicole, El-Darzi, Natalia, Mast, Sandra S, Hammer, Tim F, Dorweiler, Julia V, Busik, Irina A, Pikuleva
Publikováno v:
Journal of lipid research.
CYP46A1 is a CNS-specific enzyme, which eliminates cholesterol from the brain and retina by metabolism to 24-hydroxycholesterol, thus contributing to cholesterol homeostasis in both organs. 2-Hydroxypropyl-β-cyclodextrin (HPCD), an FDA approved form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b97c7d98f38abf5f66478c8f7e2eb22
https://pubmed.ncbi.nlm.nih.gov/36586438
https://pubmed.ncbi.nlm.nih.gov/36586438
Autor:
Micheli S. Sielski, Denis A. Proshlyakov, Ana Leda F. Longhini, Mariana Dupont, Dibyendu Chakraborty, Delaney McFarland, Maria B. Grant, Tim F. Dorweiler, Julia V. Busik, Gail M. Seigel, Sergio Li Calzi, Sandra S Hammer, Todd A. Lydic, Cristiano P. Vieira, Yan Levitsky, Yvonne Adu-Agyeiwaah, Maximilian Sandler, Bright Asare-Bediako
Publikováno v:
Diabetologia
AIMS/HYPOTHESIS: Homo Sapiens evolved under conditions of intermittent food availability and prolonged fasting between meals. Periods of fasting are important for recovery from meal-induced oxidative and metabolic stress, and tissue repair. Constant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f08e15b4aa45aa1a024b6a3de88eab5
https://europepmc.org/articles/PMC8236268/
https://europepmc.org/articles/PMC8236268/
Autor:
Kiera Fisher, Yan Levitsky, Artem Muchnik, Denis A. Proshlyakov, Nathan L. Frantz, Julia V. Busik, Sandra S Hammer, Philip Kirschner, David Pegouske, Jason N. Bazil, Anand R. Saripalli
Publikováno v:
RSC advances. 9(57)
Oxygen consumption is a key metric of metabolism in aerobic organisms. Current respirometric methods led to seminal discoveries despite limitations such as high sample demand, exchange with atmospheric O(2), and cumulative titration protocols leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b76d11e0fe615a36887b34bc378149c
https://pubmed.ncbi.nlm.nih.gov/32123561
https://pubmed.ncbi.nlm.nih.gov/32123561
Autor:
Sergio Li Calzi, Mariana Dupont, Sandra S Hammer, David K. Crossman, Maria B. Grant, Yvonne Adu-Agyeiwaah, Ana Leda F. Longhini, Masroor Hossain, Todd A. Lydic, Cristiano P. Vieira, Julia V. Busik, Seth D. Fortmann, Bright Asare-Bediako, Micheli S. Sielski, Jason L. Floyd, Robert S. Welner, Gary J. Blanchard
In diabetic dyslipidemia, cholesterol accumulates in the plasma membrane, decreasing fluidity and thereby suppressing the ability of cells to transduce ligand-activated signaling pathways. Liver X receptors (LXRs) are the main cellular mechanism by w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be238fadbed9528500eeafb9c86154f7
Autor:
Kiera Fisher, Chao Huang, Julia V. Busik, Sandra S Hammer, Svetlana Navitskaya, Gary J. Blanchard
Publikováno v:
Diabetes
Diabetic retinopathy (DR) is a microvascular complication of diabetes and is the leading cause of vision loss in working-age adults. Recent studies have implicated the complement system as a player in the development of vascular damage and progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9108bbd915d78a64df7931fc46ec849
https://doi.org/10.2337/db17-1587
https://doi.org/10.2337/db17-1587
Autor:
Goldis Malek, Daniel R. Saban, Todd A. Lydic, Moshe Levi, Sugata Hazra, Maria B. Grant, Kiana Wood, Julia V. Busik, Qi Wang, Sandra S Hammer, Xiaoxin X. Wang, Nermin Kady, Eleni Beli
Publikováno v:
EBioMedicine, Vol 22, Iss C, Pp 181-190 (2017)
EBioMedicine
EBioMedicine
Diabetic retinopathy (DR) is a complication secondary to diabetes and is the number one cause of blindness among working age individuals worldwide. Despite recent therapeutic breakthroughs using pharmacotherapy, a cure for DR has yet to be realized.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb039068c864f2fa3b506f2c435c4078
https://doi.org/10.1016/j.ebiom.2017.07.008
https://doi.org/10.1016/j.ebiom.2017.07.008
Autor:
Bright Asare-Bediako, Julia V. Busik, Ana Leda F. Longhini, Maximilian Sandler, Sandra S Hammer, Yan Levitsky, Micheli S. Sielski, Gail M. Seigel, Sergio Li Calzi, Todd A. Lydic, Cristiano P. Vieira, Delaney McFarland, Dorweiler Tf, Yvonne Adu-Agyeiwaah, Maria B. Grant, Denis A. Proshlyakov, Dibyendu Chakraborty, Mariana Dupont
SummaryIn diabetes, the retina, a tissue with unique metabolic needs, demonstrates dysregulation of the intricate balance between nutrient availability and utilization. This results in cholesterol accumulation, pro-inflammatory and pro-apoptotic chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af15a5f2cd90cf0ad6ec6a06e71edcf1
Autor:
Gary W. McCollum, Sara R. Savage, Carla Jhoana Ramos, Sandra S. Hammer, John S. Penn, Rong Yang, Megan E. Capozzi, Colin A. Bretz
Publikováno v:
Exp Eye Res
Diabetic retinopathy (DR) is triggered by retinal cell damage stimulated by the diabetic milieu, including increased levels of intraocular free fatty acids. Free fatty acids may serve as an initiator of inflammatory cytokine release from Muller cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1453827888607118f028529734b99721
https://europepmc.org/articles/PMC7426872/
https://europepmc.org/articles/PMC7426872/