Haptoglobin gene polymorphisms and interleukin-6 and -8 levels in patients with sickle cell anemia

Autor: Perla Vicari, Bruna Spinella Pierrot-Gallo, Sandra S Matsuda, Maria Stella Figueiredo, Grazielle Mecabo, Samuel Ademola Adegoke

Publikováno v: Revista Brasileira de Hematologia e Hemoterapia v.37 n.5 2015
Revista brasileira de hematologia e hemoterapia
Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC)
instacron:ABHHTC
Revista Brasileira de Hematologia e Hemoterapia
Revista Brasileira de Hematologia e Hemoterapia, Vol 37, Iss 5, Pp 329-335 (2015)
Revista Brasileira de Hematologia e Hemoterapia, Volume: 37, Issue: 5, Pages: 329-335, Published: OCT 2015

BackgroundHaptoglobin genotypes, and interleukin-6 and -8 participate in the pathophysiology of sickle cell anemia. The expression of cytokines is regulated by genetic mechanisms however the effect of haptoglobin polymorphisms on these cytokines is n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc1b5a8c425c18c533c2795ce0f37f0

Antioxidant vitamins C and E supplementation increases markers of haemolysis in sickle cell anaemia patients: a randomized, double-blind, placebo-controlled trial

Autor: Maria Stella Figueiredo, Iara Baldim Rabelo, Sandra S Matsuda, Celso A. Rodrigues, Grazielle Mecabo, Martha Mariana de Almeida Santos Arruda

Publikováno v: British journal of haematology. 160(5)

Erythrocytes from sickle cell anaemia (SCA) patients continuously produce larger amounts of pro-oxidants than normal cells. Oxidative stress seems to primarily affect the membrane and results in haemolysis. The use of antioxidants in vitro reduces th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4556e6ec196225c89ceb941e3f5d2ad2
https://pubmed.ncbi.nlm.nih.gov/23278176

Analysis of protein profile expressed on the membrane surface of plasma cells, stromal cells and mononuclear cells from bone marrow microenvironment of multiple myeloma patients by mass spectrometry

Autor: Sandra S Matsuda, Alisson L. Matsuo, Adriana Fp Leme, Bianca Alves Pauletti, Edgar J. Paredes-Gamero, Walter Mt Braga, Maria de Lourdes Lf Chauffaille, Gisele Wb Colleoni, Fabricio de Carvalho

Publikováno v: BMC Proceedings

Background Multiple Myeloma (MM) is a malignant proliferation of B-cells with plasma cell differentiation. Interactions of plasma cells with stromal cells and other cells in bone marrow (BM) microenvironment are responsible for MM progression. Screen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acadc9ec6133dfcbeb614bd33a24c0f
http://europepmc.org/articles/PMC3624661

Antioxidant Vitamins C and E Supplementation Does Not Improve the Hemolytic Profile of Sickle Cell Anemia Patients: A Randomized, Double-Blind, Placebo-Controlled Trial

Autor: Maria Stella Figueiredo, Martha Mariana de Almeida Santos Arruda, Celso Arrais Rodrigues, Iara Baldim Rabelo, Grazielle Mecabo, Sandra S Matsuda

Publikováno v: Blood. 118:1063-1063

Abstract 1063 Background: Erythrocytes of sickle cell anemia (SCA) patients continuously produce larger amounts of pro-oxidants than normal cells, and oxidative stress seems to play a significant role in the pathophysiology of this disease. In erythr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::724d866c6797608b3999a425a26da268
https://doi.org/10.1182/blood.v118.21.1063.1063