Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sandra Sánchez-Gregorio"'
Autor:
Iñaki Eguren-Santamaría, Inmaculada Rodríguez, Claudia Herrero-Martin, Eva Fernández de Piérola, Arantza Azpilikueta, Sandra Sánchez-Gregorio, Elixabet Bolaños, Gabriel Gomis, Paula Molero-Glez, Enrique Chacón, José Ángel Mínguez, Santiago Chiva, Fernando Diez-Caballero, Carlos de Andrea, Álvaro Teijeira, Miguel F. Sanmamed, Ignacio Melero
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Biomarkers for cancer immunotherapy are an unmet medical need. The group of Daniela Thommen at the NKI recently reported on novel methodologies based on short-term cultures of patient-derived tumor fragments whose cytokine concentrations in the super
Externí odkaz:
https://doaj.org/article/09779cffd119438d95ea60cb833a5d60
Autor:
Assunta Cirella, Elixabet Bolaños, Carlos Luri-Rey, Claudia Augusta Di Trani, Irene Olivera, Gabriel Gomis, Javier Glez-Vaz, Beatrice Pinci, Saray Garasa, Sandra Sánchez-Gregorio, Arantza Azpilikueta, Iñaki Eguren-Santamaria, Karmele Valencia, Belén Palencia, Maite Alvarez, Maria C. Ochoa, Álvaro Teijeira, Pedro Berraondo, Ignacio Melero
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 668-682 (2023)
Intratumoral immunotherapy strategies for cancer based on interleukin-12 (IL-12)-encoding cDNA and mRNA are under clinical development in combination with anti-PD-(L)1 monoclonal antibodies. To make the most of these approaches, we have constructed c
Externí odkaz:
https://doaj.org/article/0cbeb48e82c4432eb1d5f41226df6231
Autor:
Assunta Cirella, Elixabet Bolaños, Claudia Augusta Di Trani, Carlos E. de Andrea, Sandra Sánchez-Gregorio, Iñaki Etxeberria, Jose Gonzalez-Gomariz, Irene Olivera, Davide Brocco, Javier Glez-Vaz, Carlos Luri-Rey, Arantza Azpilikueta, Inmaculada Rodríguez, Myriam Fernandez-Sendín, Josune Egea, Iñaki Eguren, Miguel F. Sanmamed, Belen Palencia, Alvaro Teijeira, Pedro Berraondo, Ignacio Melero
Publikováno v:
Cancer Immunology Research. 11:184-198
IL12-based local gene therapy of cancer constitutes an active area of clinical research using plasmids, mRNAs, and viral vectors. To improve antitumor effects, we have experimentally tested the combination of mRNA constructs encoding IL12 and IL18. M
Autor:
Ignacio Melero, Pedro Berraondo, Alvaro Teijeira, Belen Palencia, Miguel F. Sanmamed, Iñaki Eguren, Josune Egea, Myriam Fernandez-Sendín, Inmaculada Rodríguez, Arantza Azpilikueta, Carlos Luri-Rey, Javier Glez-Vaz, Davide Brocco, Irene Olivera, Jose Gonzalez-Gomariz, Iñaki Etxeberria, Sandra Sánchez-Gregorio, Carlos E. de Andrea, Claudia Augusta Di Trani, Elixabet Bolaños, Assunta Cirella
Supplementary figures 1-8 and supplementary table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55de1d63f2018b5b1f25ddd31b7fe707
https://doi.org/10.1158/2326-6066.22546073
https://doi.org/10.1158/2326-6066.22546073
Autor:
Ignacio Melero, Pedro Berraondo, Alvaro Teijeira, Belen Palencia, Miguel F. Sanmamed, Iñaki Eguren, Josune Egea, Myriam Fernandez-Sendín, Inmaculada Rodríguez, Arantza Azpilikueta, Carlos Luri-Rey, Javier Glez-Vaz, Davide Brocco, Irene Olivera, Jose Gonzalez-Gomariz, Iñaki Etxeberria, Sandra Sánchez-Gregorio, Carlos E. de Andrea, Claudia Augusta Di Trani, Elixabet Bolaños, Assunta Cirella
IL12-based local gene therapy of cancer constitutes an active area of clinical research using plasmids, mRNAs, and viral vectors. To improve antitumor effects, we have experimentally tested the combination of mRNA constructs encoding IL12 and IL18. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437f9c251748ad1ccee76718bd3f677d
https://doi.org/10.1158/2326-6066.c.6551084
https://doi.org/10.1158/2326-6066.c.6551084
Autor:
Paloma Sánchez-Mateos, Miguel Relloso, José Antonio Avilés, Iván Márquez-Rodas, Enrique Mercader, Jorge García-Giménez, Sandra Sánchez-Gregorio, Alba Gutiérrez-Seijo, Alejandra Gutiérrez-González, Rafael Samaniego
Supplementary Table S1. List of primary antibodies and primer sequences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c71abdab89361355b9d84ded370dc6
https://doi.org/10.1158/2326-6066.22539871
https://doi.org/10.1158/2326-6066.22539871
Autor:
Paloma Sánchez-Mateos, Miguel Relloso, José Antonio Avilés, Iván Márquez-Rodas, Enrique Mercader, Jorge García-Giménez, Sandra Sánchez-Gregorio, Alba Gutiérrez-Seijo, Alejandra Gutiérrez-González, Rafael Samaniego
Supplementary Figure S2. TAM CD14+/CD163+ are the major source of CCL20 in human melanoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bd09d6ee2c40f7d7d07eafc4e67e13
https://doi.org/10.1158/2326-6066.22539880.v1
https://doi.org/10.1158/2326-6066.22539880.v1
Autor:
Paloma Sánchez-Mateos, Miguel Relloso, José Antonio Avilés, Iván Márquez-Rodas, Enrique Mercader, Jorge García-Giménez, Sandra Sánchez-Gregorio, Alba Gutiérrez-Seijo, Alejandra Gutiérrez-González, Rafael Samaniego
The chemokine axis CCR6/CCL20 is involved in cancer progression in a variety of tumors. Here, we show that CCR6 is expressed by melanoma cells. The CCR6 ligand, CCL20, induces migration and proliferation in vitro, and enhances tumor growth and metast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fcd526a94aba36d5054bb61076a7e7e
https://doi.org/10.1158/2326-6066.c.6549205.v1
https://doi.org/10.1158/2326-6066.c.6549205.v1
Autor:
Assunta, Cirella, Elixabet, Bolanos, Claudia Augusta, Di Trani, Carlos E, de Andrea, Sandra, Sánchez-Gregorio, Iñaki, Etxeberria, Jose, Gonzalez-Gomariz, Irene, Olivera, Davide, Brocco, Javier, Glez-Vaz, Carlos, Luri-Rey, Arantza, Azpilikueta, Inmaculada, Rodriguez, Myriam, Fernandez-Sendin, Josune, Egea, Iñaki, Eguren, Miguel F, Sanmamed, Belen, Palencia, Alvaro, Teijeira, Pedro, Berraondo, Ignacio, Melero
Publikováno v:
Cancer immunology research.
Interleukin-12-based local gene therapy of cancer constitutes an active area of clinical research using plasmids, mRNAs and viral vectors. To improve antitumor effects, we have experimentally tested the combination of mRNA constructs encoding interle
Autor:
Maria C. Ochoa, Carlos Ortiz-de-Solorzano, Maria E. Rodriguez-Ruiz, Iñaki Eguren-Santamaria, Marta Abengozar-Muela, Kurt A. Schalper, Mikel Ariz, Cristina Sainz, Sandra Sánchez-Gregorio, María Villalba-Esparza, Miguel F. Sanmamed, Saray Garasa, José I. Echeveste, Jose Luis Perez-Gracia, Alvaro Teijeira, Maria D. Lozano, Ignacio Melero, Carlos E. de Andrea
Publikováno v:
The Journal of Pathology. 255:190-201
Neutrophil extracellular traps (NETs) are webs of extracellular nuclear DNA extruded by dying neutrophils infiltrating tissue. NETs constitute a defence mechanism to entrap and kill fungi and bacteria. Tumours induce the formation of NETs to the adva