Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Sandra Rozlan"'
1
Akademický článek
Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing
Autor: Sumin Jo, Shipra Das, Alan Williams, Anne-Sophie Chretien, Thomas Pagliardini, Aude Le Roy, Jorge Postigo Fernandez, Diane Le Clerre, Billal Jahangiri, Isabelle Chion-Sotinel, Sandra Rozlan, Emilie Dessez, Agnes Gouble, Mathilde Dusséaux, Roman Galetto, Aymeric Duclert, Emanuela Marcenaro, Raynier Devillier, Daniel Olive, Philippe Duchateau, Laurent Poirot, Julien Valton
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Host versus graft reaction is a major impediment to CAR-T cell immune therapy in allogeneic settings. Authors show here that CAR-T cells, engineered to be deficient in MHC I expression but to express the NK inhibitor HLA-E, are resistant to destructi
Externí odkaz: https://doaj.org/article/a2496c352a3244febe307778e8da45cb
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2
Akademický článek
Altered thymic function during interferon therapy in HCV-infected patients.
Autor: Stephanie Beq, Sandra Rozlan, Sandy Pelletier, Bernard Willems, Julie Bruneau, Jean-Daniel Lelievre, Yves Levy, Naglaa H Shoukry, Rémi Cheynier
Publikováno v: PLoS ONE, Vol 7, Iss 4, p e34326 (2012)
Interferon alpha (IFNα) therapy, despite good efficacy in curing HCV infection, leads to major side effects, in particular inducement of a strong peripheral T-cell lymphocytopenia. We here analyze the early consequences of IFNα therapy on both thym
Externí odkaz: https://doaj.org/article/573769f5fe1247f3b7ec1591b422e3bf
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3
Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing
Autor: Sumin Jo, Shipra Das, Alan Williams, Anne-Sophie Chretien, Thomas Pagliardini, Aude Le Roy, Jorge Postigo Fernandez, Diane Le Clerre, Billal Jahangiri, Isabelle Chion-Sotinel, Sandra Rozlan, Emilie Dessez, Agnes Gouble, Mathilde Dusséaux, Roman Galetto, Aymeric Duclert, Emanuela Marcenaro, Raynier Devillier, Daniel Olive, Philippe Duchateau, Laurent Poirot, Julien Valton
Publikováno v: Nature Communications
Nature Communications, 2022, 13 (1), ⟨10.1038/s41467-022-30896-2⟩
International audience; Host versus graft reaction is a major impediment to CAR-T cell immune therapy in allogeneic settings. Authors show here that CAR-T cells, engineered to be deficient in MHC I expression but to express the NK inhibitor HLA-E, ar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1a3436d990a90155e6600d3dd44af5
https://pubmed.ncbi.nlm.nih.gov/35773273
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4
Modified interferon-α subtypes production and chemokine networks in the thymus during acute simian immunodeficiency virus infection, impact on thymopoiesis
Autor: Véronique Fabre-Mersseman, Jacques Dutrieux, Stéphanie Beq, Amandine Bernard, Rosalie Ponte, Bénédicte Charmeteau-De Muylder, Rémi Cheynier, Sandra Rozlan, Magali Rancez, Suzanne Figueiredo-Morgado, Anne Couëdel-Courteille
Publikováno v: AIDS
AIDS, Lippincott, Williams & Wilkins, 2014, 28 (8), pp.1101-1113. ⟨10.1097/QAD.0000000000000249⟩
International audience; Objectives: Thymus dysfunction characterizes human/simian immunodeficiency virus (SIV) infections and contributes to physiopathology. However, both the mechanisms involved in thymic dysfunction and its precise timing remain un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d32c8a1a20cace56eba81b2b4fc198
https://doi.org/10.1097/qad.0000000000000249
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5
Initiation of c-ART in HIV-1 infected patients is associated with a decrease of the metabolic activity of the thymus evaluated using FDG-PET/computed tomography
Autor: Rodolphe Thiébaut, Jean-Daniel Lelièvre, Christine Lacabaratz, Emmanuel Itti, Yves Levy, Michel Meignan, Sandra Rozlan, Giovanna Melica, Rémi Cheynier, Aurélie Wiedemann
Publikováno v: Journal of acquired immune deficiency syndromes (1999). 61(1)
BACKGROUND The role of the thymus in the depletion or restoration of T-cell pool in HIV infection is still debatable. Studies are hampered by the lack of valuable tools to investigate thymic activity. METHODS We have evaluated thymic activity using (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6a53360f333136762bfd408f57f34e
https://pubmed.ncbi.nlm.nih.gov/22706292
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6
Altered Thymic Function during Interferon Therapy in HCV-Infected Patients
Autor: Julie Bruneau, Stéphanie Beq, Bernard Willems, Sandy Pelletier, Jean-Daniel Lelièvre, Yves Levy, Naglaa H. Shoukry, Sandra Rozlan, Rémi Cheynier
Publikováno v: PLoS ONE
Scopus-Elsevier
PLoS ONE, Vol 7, Iss 4, p e34326 (2012)
Interferon alpha (IFNα) therapy, despite good efficacy in curing HCV infection, leads to major side effects, in particular inducement of a strong peripheral T-cell lymphocytopenia. We here analyze the early consequences of IFNα therapy on both thym
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7177289e1a5e5910efc11a59caefdfba
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8
CD4+ recent thymic emigrants are infected by HIV in vivo, implication for pathogenesis
Autor: Jacques Dutrieux, Olivier Lambotte, Ana E. Sousa, Magali Rancez, Anne Louise, Aurélia Lamine, Helena Nunes-Cabaço, Sandra Rozlan, Raphaelle Parker, Véronique Fabre-Mersseman, Rémi Cheynier
Publikováno v: AIDS. Official journal of the international AIDS Society
AIDS. Official journal of the international AIDS Society, 2011, 25 (9), pp.1153-1162. ⟨10.1097/QAD.0b013e3283471e89⟩
AIDS
AIDS, Lippincott, Williams & Wilkins, 2011, 25 (9), pp.1153-1162. ⟨10.1097/QAD.0b013e3283471e89⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
OBJECTIVE: The contribution of naive CD4+ T cells to the pool of HIV-infected cells remains poorly described. This study aimed at evaluating HIV infection in naive T-cell subsets in v
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4962470f465c29f27a732f62c54b2f3d
https://hdl.handle.net/10451/20112
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9
Interleukin-7 treatment counteracts IFN-α therapy-induced lymphopenia and stimulates SIV-specific cytotoxic T lymphocyte responses in SIV-infected rhesus macaques
Autor: Rémi Cheynier, Magali Rancez, Brigitte Assouline, Jacques Dutrieux, Céline Gommet, Iann Rance, Michel Morre, Annick Lim, Véronique Fabre-Mersseman, Sandra Rozlan, Stéphanie Beq, Brigitte Lemercier, Raphaelle Parker
Publikováno v: Blood
Blood, American Society of Hematology, 2010, 116 (25), pp.5589-5599. ⟨10.1182/blood-2010-03-276261⟩
Blood, 2010, 116 (25), pp.5589-5599. ⟨10.1182/blood-2010-03-276261⟩
Interferon-α (IFN-α)–based therapy is presently the standard treatment for hepatitis C virus (HCV)–infected patients. Despite good effectiveness, this cytokine is associated with major side effects, including significant lymphopenia, that limit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2397558ca14957c9ab2c9f95c0d72f1
https://hal.archives-ouvertes.fr/hal-02993039
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10
Injection of glycosylated recombinant simian IL-7 provokes rapid and massive T-cell homing in rhesus macaques
Autor: Iann Rance, Sandra Rozlan, Raphaelle Parker, Clémentine Schilte, Rémi Cheynier, Brigitte Assouline, Stéphanie Beq, Pascal Lavedan, David Gautier, Veronique Mersseman, Michel Morre
Publikováno v: Blood. 114(4)
Interleukin-7 (IL-7), the principal cytokine implicated in thymopoiesis and peripheral T-cell homeostasis, is presently under evaluation in human diseases characterized by persistent lymphopenia. Unexpectedly, before the eventual IL-7–driven T-cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3673c580395d5e04653c2efba65e7ca
https://pubmed.ncbi.nlm.nih.gov/19628713
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