Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sandra Rosskopf"'
Autor:
Pedro Berraondo, Catarina Pinto, Sarah Schmidt, Henning Lauterbach, Timo Schippers, Josipa Raguz, Theresa Pölzlbauer, Mohamed Habbeddine, Sandra Rosskopf, Judith Strauß, Valentin Just, Katell Bidet Huang, Felix Stemeseder, Ethan Stewart, Jakub Jez, Klaus K. Orlinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Engineered arenavirus vectors have recently been developed to leverage the body’s immune system in the fight against chronic viral infections and cancer. Vectors based on Pichinde virus (artPICV) and lymphocytic choriomeningitis virus (a
Externí odkaz:
https://doaj.org/article/d6f7f53f92c1475190372c05efca000b
Autor:
Judith Leitner, Manuel Reithofer, Beatrice Jahn-Schmid, Sandra Rosskopf, Peter Steinberger, Barbara Bohle, Claire Battin
Publikováno v:
European Journal of Immunology
Costimulatory signals potently promote T‐cell proliferation and effector function. Agonistic antibodies targeting costimulatory receptors of the TNFR family, such as 4‐1BB and CD27, have entered clinical trials in cancer patients. Currently there
Autor:
Wolfgang Poeppl, Veronique Touzeau-Roemer, Sandra Rosskopf, Peter Steinberger, Armin Rieger, Katharina Grabmeier-Pfistershammer, Kay Holleis
Publikováno v:
Wiener Klinische Wochenschrift
Summary Current Advisory Committee on Immunization Practices (ACIP) guidelines recommend immunization of all human immunodeficiency virus (HIV)-infected patients against meningitis serotype ACWY due to recent outbreaks of meningitis C in homosexual m
Autor:
Johana A. Luna Coronell, Andreas Weinhäusel, István Gyurján, Sandra Rosskopf, Daniela Muhr, Christian F. Singer
Publikováno v:
Oncotarget
Background: Breast cancer is the most frequent and one of the most fatal malignancies among women. Within the concept of personalized medicine, molecular characterization of tumors is usually performed by analyzing somatic mutations, RNA gene express
Autor:
Josipa Raguz, Theresa Kleissner, Sandra Rosskopf, Mohamed Habbeddine, Katharina Lechner, Valentin Just, Donna Edwards, Igor Matushansky, Christoph Lampert, Klaus K. Orlinger, Henning Lauterbach
Publikováno v:
Cancer Research. 82:2048-2048
Cytotoxic CD8+ T cells are paramount for effective cancer immunotherapy. We engineered two distantly related arenaviruses, lymphocytic choriomeningitis virus (LCMV) and Pichinde virus (PICV), encoding the same non-oncogenic HPV16 E7E6 fusion protein
Autor:
Jordan Phelan, Ernst Malle, Naina Gour, Peter A. Tauber, Ursula Smole, Leonardo Puerta, Gerhard Hofer, Xiao Xiao, Luis Caraballo, Marsha Wills-Karp, Nu Yao, Bernhard Kratzer, Jan Dvorak, Cordula Köhler, Andrew P. Lane, Stephane Lajoie, Jamila Chakir, Sandra Rosskopf, Winfried F. Pickl
Publikováno v:
Nature immunology. 21(7)
The molecular basis for the propensity of a small number of environmental proteins to provoke allergic responses is largely unknown. Herein, we report that mite group 13 allergens of the fatty acid-binding protein (FABP) family are sensed by an evolu
Publikováno v:
Cancer Immunology, Immunotherapy
Immune checkpoint inhibitors targeting coinhibitory pathways in T cells possess efficacy in combating cancer. In addition to PD-1/PD-L1 and CTLA-4 antibodies which are already established in tumor immunotherapy, immune checkpoints such as LAG-3 or BT
Autor:
Sandra, Rosskopf, Judith, Leitner, Wolfgang, Paster, Laura T, Morton, Renate S, Hagedoorn, Peter, Steinberger, Mirjam H M, Heemskerk
Publikováno v:
Oncotarget
Adoptive T cell therapy using TCR transgenic autologous T cells has shown great potential for the treatment of tumor patients. Thorough characterization of genetically reprogrammed T cells is necessary to optimize treatment success. Here, we describe
Autor:
Gerhard J. Zlabinger, Peter Steinberger, Markus Zettl, Armin Rieger, Sandra Rosskopf, Carmen Stecher, Katharina Grabmeier-Pfistershammer
Publikováno v:
Clinical immunology (Orlando, Fla.). 183
Persistent stimulation with antigens derived from viruses that establish chronic infections or tumour antigens results in the exhaustion of T cells. Coinhibitory receptors like PD-1 and CTLA-4 function as immune checkpoints on exhausted T cells. Bloc