Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Sandra Rossie"'
Autor:
Christopher J. Petell, Lama AlAbdi, Lanchen Wu, Sandra Rossie, Humaira Gowher, Allison B. Norvil
Publikováno v:
Biochemistry. 57:4312-4324
The catalytic domains of the de novo DNA methyltransferases Dnmt3a-C and Dnmt3b-C are highly homologous. However, their unique biochemical properties could potentially contribute to differences in the substrate preferences or biological functions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a596968c2c95a3029dcc9249b889769d
https://doi.org/10.1021/acs.biochem.6b00964
https://doi.org/10.1021/acs.biochem.6b00964
Autor:
Sandra Rossie, Kavita Shah
Publikováno v:
Molecular neurobiology. 55(4)
Cdk5 kinase, a cyclin-dependent kinase family member, is a key regulator of cytoskeletal remodeling in the brain. Cdk5 is essential for brain development during embryogenesis. After birth, it is essential for numerous neuronal processes such as learn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469b603e16a3783184f9982912661f72
https://pubmed.ncbi.nlm.nih.gov/28502042
https://pubmed.ncbi.nlm.nih.gov/28502042
Autor:
Ling Wang, Navdeep Jaitly, Hemalatha Jayachandran, Sandra Rossie, Ashoka D. Polpitiya, Matthew E. Monroe, Bryan M. Ham, Rui Zhao, Feng Yang, Richard D. Smith, Eric A. Livesay, David G. Camp, Samuel O. Purvine
Publikováno v:
Journal of Proteome Research. 9:945-953
The DNA damage response likely includes a global phosphorylation signaling cascade process for sensing the damaged DNA condition and coordinating responses to cope with and repair the perturbed cellular state. We utilized a label-free liquid chromato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108587aae63bee5450e264eb33553578
https://doi.org/10.1021/pr9008207
https://doi.org/10.1021/pr9008207
Publikováno v:
Journal of Neurochemistry. 111:391-402
Amyloid-beta (Abeta) is thought to promote neuronal cell loss in Alzheimer's disease, in part through the generation of reactive oxygen species (ROS) and subsequent activation of mitogen-activated protein kinase (MAPK) pathways. Protein phosphatase 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f58d5232dd52f062b9bffd86000590d
https://doi.org/10.1111/j.1471-4159.2009.06337.x
https://doi.org/10.1111/j.1471-4159.2009.06337.x
Publikováno v:
Brain Research. 1111:1-11
Glucocorticoid receptors are widely expressed in brain, where they are thought to play a role in controlling neurogenesis and to mediate many of the central nervous system effects of stress. In non-neuronal cells, protein phosphatase 5 (PP5) has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f44eb4d55f41d735713c0fedec6058b
https://doi.org/10.1016/j.brainres.2006.06.106
https://doi.org/10.1016/j.brainres.2006.06.106
Autor:
Yufeng Shen, Kim K. Hixson, Sandra Rossie, Keqi Tang, Ronald J. Moore, Richard D. Smith, Ayesha Elias, Quanzhou Luo, Feng Yang, Rui Zhao
Publikováno v:
Journal of Proteome Research. 5:1091-1097
The sensitivity of proteomics measurements using liquid chromatography (LC) separations interfaced with electrospray ionization-mass spectrometry (ESI-MS) improves approximately inversely with liquid flow rate (for the columns having the same separat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72c8ffa59852f1b730774f51de9f020
https://doi.org/10.1021/pr050424y
https://doi.org/10.1021/pr050424y
Publikováno v:
Journal of Biological Chemistry. 280:1790-1796
Protein phosphatase (PP) 5 is highly expressed in the mammalian brain, but few physiological substrates have yet been identified. Here, we investigated the kinetics of dephosphoryation of phospho-tau by PP5 and found that PP5 had a K(m) of 8-13 micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::893b8a1f10966a78e46c4239eb4a9ac2
https://doi.org/10.1074/jbc.m410775200
https://doi.org/10.1074/jbc.m410775200
Autor:
Cheng-Xin Gong, Inge Grundke-Iqbal, Liang Li, Sandra Rossie, Fei Liu, Jerzy Wegiel, Guoxin Wu, Khalid Iqbal
Publikováno v:
Journal of Neurochemistry. 88:298-310
Protein phosphatase 5 (PP5) is a 58-kDa novel phosphoseryl/phosphothreonyl protein phosphatase. It is ubiquitously expressed in all mammalian tissues examined, with a high level in the brain, but little is known about its physiological substrates. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef3d100458584ae28ec1842e7df6b47d
https://doi.org/10.1111/j.1471-4159.2004.02147.x
https://doi.org/10.1111/j.1471-4159.2004.02147.x
Autor:
Kenira J Thompson, Rimple Bahl, Rodney A. Swain, Katherine C. Bradley, Robert L. Meisel, Sandra Rossie
Publikováno v:
Molecular Brain Research. 90:101-109
Protein phosphatase 5 is a recently discovered Ser/Thr phosphatase that is structurally related to calcineurin and protein phosphatases 1 and 2. Northern blot and in situ hybridization studies have shown that protein phosphatase 5 mRNA is present at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88b02d5fefd71873d0eded2dd994e25
https://doi.org/10.1016/s0169-328x(01)00089-4
https://doi.org/10.1016/s0169-328x(01)00089-4
Autor:
Harry Charbonneau, David L. Armstrong, Charles Romeo, Jeffrey Skinner, Christopher Sinclair, Sandra Rossie
Publikováno v:
Journal of Biological Chemistry. 272:22464-22471
An arachidonic acid-stimulated Ser/Thr phosphatase activity was detected in soluble extracts prepared from rat pituitary clonal GH4C1 cells, rat or bovine brain, and bovine heart. The enzyme activity was purified to homogeneity from bovine brain as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695f75775df384784b03bac42abf6b34
https://doi.org/10.1074/jbc.272.36.22464
https://doi.org/10.1074/jbc.272.36.22464