Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sandra Rolland"'
Autor:
Fayza Daboussi, Séverine Thomas, Alexandre Juillerat, Jean-Pierre Cabaniols, Céline Lebuhotel, Annabelle Gariboldi, Julien Valton, Fabien Delacôte, Sebastien Paris, Adeline Jacquet, Sandra Rolland, Domique Alain Blanchard, Marianne Duhamel, Gil Letort, Sandra Moriceau, Raffy Demirdjian, Aymeric Duclert, Roman Galetto, Philippe Duchateau, Claudia Bertonati
Publikováno v:
Methods. 69:151-170
TALEN is one of the most widely used tools in the field of genome editing. It enables gene integration and gene inactivation in a highly efficient and specific fashion. Although very attractive, the apparent simplicity and high success rate of TALEN
Autor:
Jerónimo Bravo, Christophe Perez, Guillermo Montoya, Francois Stricher, Luis Serrano, Francisco J. Blanco, Sandra Rolland, Amélie Patin, Anne-Sophie Petit, Sylvain Arnould, Emmanuel Lacroix, Aymeric Duclert, Sophie Guillier, Jesús Prieto, Jean-Charles Epinat, Patrick Chames, Frédéric Pâques, Philippe Duchateau
Publikováno v:
Journal of Molecular Biology. 355:443-458
The last decade has seen the emergence of a universal method for precise and efficient genome engineering. This method relies on the use of sequence-specific endonucleases such as homing endonucleases. The structures of several of these proteins are
Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers
Autor:
Alex Duval, Barry Iacopetta, Emmanuel Tubacher, Sandra Rolland, Richard Hamelin, Gilles Thomas, Aurore Compoint
Publikováno v:
Human Molecular Genetics. 10:513-518
A number of human genes containing coding mononucleotide repeat sequences are particularly prone to mutations in tumors with defects in mismatch repair (MMR) genes (MSI-H cancers). In a large series of MSI-H colorectal tumors, we looked for mutations
Publikováno v:
Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie. 321:877-881
The cl represser of bacteriophage λ is better-fitted to the proximal interactions in which it naturally takes part than to the long-distance cooperative interactions on DNA for which it has become representative. The first observation in support of
Autor:
Jean-Marc Hoang, Paul Cottu, Xiao-Ping Zhou, Alex Duval, Richard Hamelin, Jacqueline Gayet, Sandra Rolland
Publikováno v:
Oncogene. 20(36)
A number of genetic alterations have been described in colorectal cancers. They include allelic losses on specific chromosomal arms, mutations of oncogenes, tumor suppressor genes and mismatch repair genes, microsatellite instability in coding repeat