Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sandra Rodrigo Blomqvist"'
Autor:
Anna Lindgren, Malin Levin, Sandra Rodrigo Blomqvist, Johannes Wikström, Andrea Ahnmark, Christina Mogensen, Gerhard Böttcher, Mohammad Bohlooly-Y, Jan Borén, Li-Ming Gan, Daniel Lindén
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80330 (2013)
Adiponectin has been shown to have beneficial cardiovascular effects and to signal through the adiponectin receptors, AdipoR1 and AdipoR2. The original aim of this study was to investigate the effect of combined AdipoR1 and AdipoR2 deficiency (AdipoR
Externí odkaz:
https://doaj.org/article/98fc49635ed54b1a93274074f37cae3c
Autor:
Hilmar Vidarsson, Rickard Westergren, Mikael Heglind, Sandra Rodrigo Blomqvist, Sylvie Breton, Sven Enerbäck
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4471 (2009)
The vacuolar H(+)-ATPase dependent transport of protons across cytoplasmic membranes in FORE (forkhead related) cells of endolymphatic epithelium in the inner ear, intercalated cells of collecting ducts in the kidney and in narrow and clear cells of
Externí odkaz:
https://doaj.org/article/ab1367dec07b4dee85aa9c02d407199b
Autor:
Paraskevi Persitera, Linda L. Magnusson Hanson, Lena Låstad, Tianwei Xu, Sandra Rodrigo Blomqvist
Publikováno v:
Blomqvist, S, Xu, T, Persitera, P, Lastad, L & Hanson, L L M 2020, ' Associations between cognitive and affective job insecurity and incident purchase of psychotropic drugs : A prospective cohort study of Swedish employees ', Journal of Affective Disorders, vol. 266, pp. 215-222 . https://doi.org/10.1016/j.jad.2020.01.078
Background Previous research suggests that job insecurity is associated with poor mental health, but research examining how different aspects of job insecurity relate to clinical measures of poor mental health are lacking. We aimed to investigate the
Autor:
Anders Cavallin, Nils-Olov Hermansson, Lisa Jinton, Pia Berntsson, Mei Ding, Sandra Rodrigo Blomqvist
Publikováno v:
SLAS Discovery. 23:676-686
Immunoassays, utilizing the affinity of antibodies to their antigens, are powerful techniques and have been widely used for quantifying analytes, such as cytokines, in biological samples in the clinic and in drug discovery. Various immunoassays have
Publikováno v:
BMC Public Health
BMC Public Health, Vol 20, Iss 1, Pp 1-12 (2020)
BMC Public Health, Vol 20, Iss 1, Pp 1-12 (2020)
Background A maintained psychological wellbeing is important in order to continue working longer and remain active into older age. However, little is known about impact of different organizational factors, such as downsizing, on the mental health of
Autor:
Nils Pemberton, Cristina Gardelli, Jens Petersen, Neil S. Holden, Helena Lindmark, Pavol Zlatoidsky, Sandra Rodrigo Blomqvist, Annika Westin Eriksson, Rhona J. Cox, Linda Öster, Christian Tyrchan, Susanne Arlbrandt, Sarah Lever, Perry Matthew, Bold Peter, Mickael Mogemark, Matthew F. Thomas, A. Monica Norberg, Kostas Karabelas, Johan Karlsson, Xueshan Li
Publikováno v:
'Journal of Medicinal Chemistry ', vol: 61, pages: 5435-5441 (2018)
In this paper, we describe the discovery and optimization of a new chemotype of isoform selective PI3Kγ inhibitors. Starting from an HTS hit, potency and physicochemical properties could be improved to give compounds such as 15, which is a potent an
Autor:
Christian Tyrchan, Neil S. Holden, Nils Pemberton, Anders Eriksson, Ina Terstiege, Yunhua Chen, Hai'e Hao, Kostas Karabelas, Karin Björhall, Tor Svensson, Linda Fredlund, Wenzhen Yang, Jens Petersen, Shuchun Zhao, Perry Matthew, Johan Carlsson, Helena Lindmark, Sandra Rodrigo Blomqvist, Britta Bonn, Feifei Liu, Reed W. Smith, Linda Öster
Publikováno v:
Journal of medicinal chemistry. 60(12)
PI3Kδ is a lipid kinase that is believed to be important in the migration and activation of cells of the immune system. Inhibition is hypothesized to provide a powerful yet selective immunomodulatory effect that may be beneficial for the treatment o
Autor:
Karin Björhall, Paulina Cygan, Matthew Thomas, Rose A. Maciewicz, Johan Carlsson, Carla Winkler, Maria Karlsson, Mickael Mogemark, Maria Nordberg, Vikki Morrison, Andrew Butcher, Perry Matthew, Helena Lindmark, Sandra Rodrigo Blomqvist, Bold Peter, Carl S. Goodyear, Kostas Karabelas
Publikováno v:
3.2 Airway Cell Biology and Immunopathology.
Introduction Severe asthma can be dominated by either Th2/eosinophilic or Th17/neutrophilic pathology yet the specific endotype of a patient may not be clear/stable. We hypothesized that a locally administered PI3kγδ dual isoform inhibitor could pr
Autor:
Britta Bonn, Neil S. Holden, Perry Matthew, Rikard Pehrson, Matthew F. Thomas, Susanne Arlbrandt, Sandra Rodrigo Blomqvist, Karin Björhall, Kostantinos Karabelas, Mohib Uddin
Publikováno v:
5.3 Allergy and Immunology.
Publikováno v:
Developmental Biology. 298:430-441
Members of the Eyes absent (Eya) gene family are important for auditory system development. While mutations in human EYA4 cause late-onset deafness at the DFNA10 locus, mutations in human EYA1 cause branchio–oto–renal (BOR) syndrome. Inactivation